Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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For the 61 residents, the average age of the residents was 87 years, with 61% being female and 69% having dementia as the primary diagnosis.
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Elderly people affected by Mild Cognitive Impairment (MCI) usually report a perceived decline in cognitive functions that deeply impacts their quality of life.
Why it matters
This paper proposes combining virtual reality and artificial intelligence to detect mild cognitive impairment earlier using digital biomarkers such as gait. It is a proposed approach, not a tested treatment or prevention.
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Globally, 985 million women are aged 50 and over, leading to increasing concerns about chronic conditions such as cardiovascular disease, osteoporosis, dementia, and cognitive decline, which can adversely affect quality of life and independent living.
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We urge the field to rethink metrics to account for diverse intra-individual experiences and trajectories of loneliness.
Why it matters
This review argues that current loneliness interventions are unsuccessful because they treat loneliness as a uniform construct and are not targeted at individuals' needs and contexts. It calls for a precision health approach to move interventions from treatment toward prevention.
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Cognitive decline because of aging and neurodegeneration has become increasingly prevalent.
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Changes in gait, especially decreased gait velocity, may be a harbinger of cognitive decline in aging.
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Medial temporal lobe dependent cognitive functions are highly vulnerable to hypoxia in the hippocampal region, yet little is known about the relationship between the richness of hippocampal vascular supply and cognition.
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Virtual reality use was generally safe and enjoyable in hPLWD.
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Postoperative cognitive dysfunction (POCD) is a common disorder following surgery, which seriously threatens the quality of patients' life, especially the older people.
Why it matters
This review states that the underlying cause of postoperative cognitive dysfunction remains inconclusive because of conflicting results and controversial evidence. It notes a link between POCD and conditions such as dementia, but offers no treatment or cure.
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The machine learning algorithm for NPTs has suggested potential use as a reference in differentiating cognitive impairment in the clinical setting.
Why it matters
A machine learning model trained on multi-center neuropsychological test data identified cognitive impairment and distinguished normal cognition, mild cognitive impairment and Alzheimer's disease dementia with high accuracy. This could help streamline diagnosis, but it does not provide a treatment, cure or prevention.
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Cognitive impairment and dementia continue to threaten the aging population.
Why it matters
This paper proposes that social conditions such as discrimination, education and socioeconomic status raise stress levels in black older persons, which can affect the body and lead to more cognitive impairment or dementia. It offers a framework for thinking about these pathways rather than testing a treatment or cure.
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The aging population is expanding, as is the prevalence of age-related cognitive decline (ARCD).
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Neurological illnesses, including cognitive impairment, memory decline and dementia, affect over 50 million people worldwide, imposing a substantial burden on individuals and society.
Why it matters
This review suggests that adverse early-life experiences, especially in the perinatal period, may influence brain circuit maturation and contribute to later vulnerability to cognitive illnesses. It is a review of early-life risk factors and does not test any treatment, cure, or prevention for Alzheimer's disease.
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Experiences translated into four themes: acknowledging human dignity; being recognised as an important caregiver; (not) talking about death and dying and making decisions together.
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45/100
Neurosyphilis is caused by the bacterium Treponema pallidum subspecies pallidum ( T. pallidum ).
Why it matters
This review describes neurosyphilis, an infection caused by the bacterium Treponema pallidum, which in its late stages can include dementia paralytica. It concerns a different, treatable cause of dementia and provides no evidence on treating, curing, or preventing Alzheimer's disease.
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A gap of knowledge, of information and in care intertwiningly hinder advance care planning.
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Educational programs may be useful in reducing racial differences in attitudes towards ACP.
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Dementia is a devastating disease and global health challenge that is highly prevalent worldwide.
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Bipolar disorders were associated with greater, whereas Li treatment with lower discrepancy between brain and chronological age.
Why it matters
In people with bipolar disorders, lithium treatment was associated with lower discrepancy between brain and chronological age, suggesting neuroprotective effects that may generalize to neurodegenerative disorders. This study did not directly examine Alzheimer's disease treatment, cure, or prevention.
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Assistive technology (AT) involvement in therapeutic treatment has provided simple and efficient healthcare solutions to people.
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A total of 41 articles met the eligibility criteria.
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There is little direct evidence that underground railway particulate matter exposure is more harmful than ambient particulate matter exposure.
Why it matters
This review found that in vitro studies suggest underground railway particulate matter may be more toxic than ambient particulate matter, but the implications for the health of exposed commuters and employees are unclear. It reports no findings on treating, curing, or preventing Alzheimer's disease.
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Diabetes is becoming one of the most widespread health burning problems in the elderly.
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This article reviews two of the primary progressive aphasias (PPAs), disorders characterized by the early and predominant impairment of language, and primary progressive apraxia of speech, a degenerative motor speech disorder that is closely related to PPA.
Why it matters
This review describes primary progressive aphasias and primary progressive apraxia of speech, noting evidence that primary progressive apraxia of speech is a distinct degenerative disorder. It suggests emphasizing agrammatism as the core inclusion criterion for nonfluent/agrammatic variant primary progressive aphasia and not including patients with isolated or predominant apraxia of speech.
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Of the 15 articles that were included, most used qualitative methods (N = 13) and were conducted in long-term care facilities (N = 14).
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- A Powerful Approach to Estimating Annotation-Stratified Genetic Covariance via GWAS Summary Statistics
- Education, Occupational Complexity, and Incident Dementia: A COSMIC Collaborative Cohort Study
- Effect of Multidomain Intervention, Omega-3 Polyunsaturated Fatty Acids Supplementation or their Combinaison on Cognitive Function in Non-Demented Older Adults According to Frail Status: Results from the MAPT Study
- Effect of a Multicomponent Program on the Prevention of Cognitive Decline and Dementia
- The Timecourse of Global Cognitive Gains from Supervised Computer-Assisted Cognitive Training: A Randomised, Active-Controlled Trial in Elderly with Multiple Dementia Risk Factors
- Making decisions for people with dementia who lack capacity: qualitative study of family carers in UK
- Influence of hospice on nursing home residents with advanced dementia who received Medicare-skilled nursing facility care near the end of life
- Fatty acid intake and the risk of dementia and cognitive decline: a review of clinical and epidemiological studies
- Lifespan Intellectual Factors, Genetic Susceptibility, and Cognitive Phenotypes in Aging: Implications for Interventions
- Cognitive impairment in patients with AIDS - prevalence and severity