Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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This reduction is likely a consequence of the COVID-19 pandemic, which may have decreased overall diagnostic opportunities.
Why it matters
This county-level analysis examined whether the 2020 CMS telehealth expansion changed diagnosed prevalence of Alzheimer's disease and related dementias. Average county-level prevalence fell from 11.06% before the expansion to 7.15% after, a reduction the authors say was likely due to the COVID-19 pandemic decreasing diagnostic opportunities.
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Why it matters
This item is only a supplementary file with no summary or findings about Alzheimer's disease. It provides no information relevant to treating, curing, or preventing Alzheimer's disease.
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The overall advance care planning behavioural intention was at a moderately high level.
Why it matters
This mixed-methods study found that advance care planning intention among people with dementia was at a moderately high level, and was positively associated with higher education, certain religious beliefs, greater knowledge, positive attitudes, and stronger subjective norms. Qualitative themes included positive attitude but limited awareness, supportive relationships enabling early consideration, and cultural norms shaping willingness to engage.
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This study aims to analyze the spatial planning and operational strategies of three profile nursing homes in Copenhagen, Denmark-Hørgården, Peder Lykke Center, and Ørestad Plejecenter-and to derive design and operational implications for the development of Korean unit-based long-term care facilities for older adults.
Why it matters
This case study analyzed spatial planning and operational strategies of three Danish nursing homes to derive design implications for Korean long-term care facilities, including dementia-friendly design. It does not address treating, curing, or preventing Alzheimer's disease.
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Alzheimer’s disease and related dementias (ADRD) disproportionately impact older Black American adults, with diet-related cardiometabolic conditions contributing to increased risk.
Why it matters
The MIND+SOUL program co-developed a culturally tailored dietary intervention with community partners for older Black American adults at risk of Alzheimer's disease and related dementias. Preliminary findings suggest high engagement and improved dietary intake, but this is early work and does not yet show that the program prevents dementia.
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32/100
For people with dementia (n = 6), readiness was facilitated by a desire for autonomy.
Why it matters
This qualitative interview study found that readiness for advance care planning in dementia was helped by a desire for autonomy and hindered by focusing on the present, avoiding sensitive topics, and relying on healthcare professionals to start discussions. It suggests that improving readiness may depend on collaboration, social support, and healthcare professionals' training and organizational support, not on any treatment for the disease itself.
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Appendix B. Coding tree of main categories and specific sub categories describing factors influencing readiness for advance care planning among people with dementia, family caregivers, and healthcare professionals.
Why it matters
This appendix presents a coding tree of categories and subcategories describing factors that influence readiness for advance care planning among people with dementia, family caregivers, and healthcare professionals. It contains no testing of any treatment, so it offers no information on treating, curing, or preventing Alzheimer's disease.
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Appendix A. Interview guides on experiences with advance care planning, factors influencing readiness for advance care planning, and the use of conversation aids among people with dementia, family caregivers, and healthcare professionals.
Why it matters
This appendix provides the interview guides used to explore experiences with advance care planning, factors influencing readiness for it, and the use of conversation aids among people with dementia, family caregivers, and healthcare professionals. It reports no treatment or outcome results, so it offers no information on treating, curing, or preventing Alzheimer's disease.
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MoCA scores showed significant positive correlations with cognitive-related cerebellar regions, particularly the left Crus I lobule (r = 0.40, p = 0.02) and total Crus I volume (r = 0.36, p = 0.04).
Why it matters
In this imaging study, MoCA scores correlated with certain cerebellar regions while MMSE scores correlated with only one, suggesting MoCA may better detect cerebellar-related cognitive impairment. This concerns diagnosis and brain measurement, not treatment, cure or prevention.
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32/100
Reasons for declining included mis-association with hospice, not seeing additional benefit to current care, and reluctance to change current care.
Why it matters
This study describes reasons older adults decline community-based palliative care, such as mis-association with hospice. It does not address treating, curing, or preventing Alzheimer's disease.
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Instrumental assessments (Videofluoroscopic Swallowing Study [VFSS], Fiberoptic Endoscopic Evaluation of Swallowing [FEES]) and the Water Swallow Test were most frequently used.ICF mapping revealed that 96.7% of tools focused on body functions, while only approximately 20% addressed participation and environmental factors.
Why it matters
This review of swallowing assessment tools found most focus on body functions and few address eating activities or the person's environment. It calls for new standardised tools to guide rehabilitation and improve quality of life, but reports no treatment or cure.
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VARABOM.D scores showed significant positive associations with established cognitive assessments.
Why it matters
This study found that a virtual reality-based cognitive assessment tool had accuracy comparable to traditional assessments and was safe and feasible. It is about improving cognitive screening, not about treating, curing, or preventing Alzheimer's disease.
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The MoCA shows superior sensitivity for MCI detection compared to the Mini-Mental State Examination (MMSE), with strengths in brevity, multidomain coverage, and accessibility.
Why it matters
This review discusses the strengths and limitations of the Montreal Cognitive Assessment for detecting mild cognitive impairment. It recommends that the tool should not be used in isolation and that refinements are needed, but it does not report any treatment, cure, or prevention for Alzheimer's disease.
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Object On the basis of determining the clinical effect of moxibustion on vascular dementia (VD), this study explored the central mechanism of moxibustion on VD through fMRI.
Why it matters
In this small study, moxibustion treatment was followed by improved scores on two cognitive tests in people with vascular dementia. The brain imaging changes seen after treatment suggest altered brain activity, but the study did not test whether this slows or prevents dementia.
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32/100
Key barriers included limited digital literacy, resistance to technology and privacy concerns, as well as competing organisational priorities, and inadequate technological infrastructure.
Why it matters
This evaluation of an online tool for rural dementia caregivers found key barriers including limited digital literacy, resistance to technology, privacy concerns, and inadequate infrastructure. It concludes that addressing digital literacy, infrastructure, and organizational readiness is essential for future technology-based health interventions in rural dementia care.
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Persons with dementia were significantly more likely to enter HHC directly from the community (60% vs. 37%, adjusted OR = 1.52, 95% CI = 1.50-1.53).
Why it matters
This study compared how people with and without dementia entered home health care in traditional Medicare versus Medicare Advantage. It found people with dementia were more likely to enter home health directly from the community, and those in Medicare Advantage were less likely to do so, which is about access to care rather than treating or preventing dementia.
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The Dementia Datahub (https://dementiadatahub.org/) currently provides mapping, data reporting dashboards, system documentation, and public use files (available upon request) of statistics from the year 2020.
Why it matters
The Dementia DataHub is a public surveillance resource offering 2020 statistics on diagnosed dementia prevalence, incidence, mortality, COVID-19 infections and Medicare expenditures at national, state and county levels. It is a data tool for organizations working on dementia, not a study of any treatment, cure or prevention.
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Successfully embedding technology into long-term care settings requires intentional, evidence-based community engagement strategies that address the unique needs of providers, caregivers, and persons living with dementia.
Why it matters
This presentation describes implementing a mobile health app in rural adult day centers to improve communication between staff and family caregivers of persons living with dementia. Findings come from only 2 centers and 17 participants and concern information-sharing and care coordination, not treatment, cure, or prevention of Alzheimer's disease.
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32/100
Overall, our findings suggest that greater neighborhood disadvantage may influence select domains of memory, and that one’s self-reported loneliness may influence how this relationship manifests.
Why it matters
In 136 older adults, greater neighborhood disadvantage was linked to worse short-term and long-term nonverbal memory. Loneliness changed the strength of the link between national neighborhood disadvantage and both types of nonverbal memory.
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Specifically, higher inflammation was associated with worse processing speed (B = -0.01; p < .05) and working memory (B = 8323.66; p < .1) only among those from more disadvantaged neighborhoods.
Why it matters
In a small sample of 51 older adults, higher inflammation was linked to worse processing speed and working memory only among those living in more disadvantaged neighborhoods. This early finding suggests social context may shape how inflammation relates to cognition.
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Advance care planning (ACP) in dementia has been defined as a communication process adapted to the person’s capacity, which includes, and is continued with family, in our European Association for Palliative Care Delphi study Delphi study with an expert panel from 33 countries.
Why it matters
This Delphi study with an international expert panel found consensus that advance care planning discussions can refer to the end of life but need not, while noting concerns about emotional harm and missed opportunities. It is about communication in care planning, not treating, curing or preventing Alzheimer's disease.
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Palliative care should be introduced as a culturally tailored set of services to assist families in ways that align with their values and caregiving practices.
Why it matters
In interviews with 19 Latino family caregivers of persons with dementia, none of the participants were familiar with palliative care, and caregivers described personal and health challenges. This small qualitative study identifies cultural and awareness gaps in palliative care delivery and does not test any treatment, cure, or prevention for Alzheimer's disease.
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Antecedents of acute care use and poor prognosis may suggest late utilization of palliative care among PLWD and lack of palliative care needs screening.
Why it matters
This concept analysis of 16 studies clarifies that palliative care for community-dwelling persons with dementia differs from hospice and does not require being near end of life, and that its consequences include more home deaths and less burdensome acute care use. It addresses care delivery and quality of life, not treating, curing, or preventing Alzheimer's disease.
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Thirty caregiver-patient dyads were followed longitudinally.
Why it matters
This small longitudinal study of 30 caregiver-patient dyads found significant caregiver distress in prion disease, with higher burden linked to younger age at disease onset. The authors note that small sample size and disease heterogeneity limited the analyses, and they call for larger studies.
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Home-visit nursing can reduce early readmissions and improve quality of life in older patients with heart failure (HF).
Why it matters
In this retrospective study of 88 patients with heart failure in Japan, Long-Term Care Insurance certification was associated with fewer early home-visit nursing visits. There was no significant association between certification and activities of daily living level.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Mediterranean diet and mild cognitive impairment
- Promising strategies for the prevention of dementia
- Melatonin for treatment of sundowning in elderly persons with dementia - a preliminary study
- Population-Based Estimates of 1-Year Mortality After Major Surgery Among Community-Living Older US Adults
- Treatment of nursing home residents with dementia and lower respiratory tract infection in the United States and The Netherlands: an ocean apart
- Gait analysis in older adults with mild cognitive impairment: a bibliometric analysis of global trends, hotspots, and emerging frontiers
- Neuropathologic comorbidity and cognitive impairment in the Nun and Honolulu-Asia Aging Studies
- Deep neural networks and genome-wide associations reveal the polygenic architecture of local brain aging
- Quality end-of-life care for dementia: What have family carers told us so far? A narrative synthesis
- A multinational cohort study of trends in survival following dementia diagnosis