Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. Cognitive Reserve in Dementia: Implications for Cognitive Training

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in aging neuroscience 2016-04-26 Prevention trials

    Cognitive reserve (CR) is a potential mechanism to cope with brain damage.

  2. A Feasibility Study with Image-Based Rendered Virtual Reality in Patients with Mild Cognitive Impairment and Dementia

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. PloS one 2016-03-18 Prevention trials

    Virtual Reality (VR) has emerged as a promising tool in many domains of therapy and rehabilitation, and has recently attracted the attention of researchers and clinicians working with elderly people with MCI, Alzheimer's disease and related disorders.

  3. Beta-Band Functional Connectivity is Reorganized in Mild Cognitive Impairment after Combined Computerized Physical and Cognitive Training

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in neuroscience 2016-02-29 Prevention trials

    Physical and cognitive idleness constitute significant risk factors for the clinical manifestation of age-related neurodegenerative diseases.

  4. Combining brain stimulation and video game to promote long-term transfer of learning and cognitive enhancement

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Scientific reports 2016-02-23 Prevention trials

    Cognitive training offers the potential for individualised learning, prevention of cognitive decline, and rehabilitation.

  5. Most HCWs recognised a need for palliative care for people with PD; however several barriers to implementing a palliative care approach in this population need to be addressed.

  6. The Differential Diagnosis and Treatment of Atypical Parkinsonism

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Deutsches Arzteblatt international 2016-02-01 Clinical safety

    Causal treatments for neurodegenerative diseases are now being developed and tested, and thus a molecular diagnosis is desirable.

  7. Advance care planning for nursing home residents with dementia: policy vs. practice

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of Advanced Nursing 2015-11-12 Health systems and care delivery

    Nursing homes generally met three quarters of the pre-defined criteria for advance care planning policy.

    Why it matters

    This study found no statistically significant correlations between advance care planning policy and actual practice in nursing homes. It concluded that while policy evaluations were promising, actual practice needs improvement.

  8. Identification of the palliative phase in people with dementia: a variety of opinions between healthcare professionals

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. BMC palliative care 2015-11-04 End-of-life care

    The results of the study identified that professionals across Europe have different opinions regarding the time point when to consider a person with dementia in need of palliative care.

  9. End of life care interventions for people with dementia in care homes: addressing uncertainty within a framework for service delivery and evaluation

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. BMC palliative care 2015-09-17 End-of-life care

    For people with dementia living and dying in care homes, EoL interventions need to provide strategies that can accommodate or "hold" the inevitable and often unresolvable uncertainties of providing and receiving care in these settings.

  10. Stress effects on the hippocampus: a critical review

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Learning & memory (Cold Spring Harbor, N.Y.) 2015-08-18 Hippocampus size on brain scans

    Uncontrollable stress has been recognized to influence the hippocampus at various levels of analysis.

  11. Dealing with behavioral and psychological symptoms of dementia: a general overview

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Psychology research and behavior management 2015-07-03 Prevention trials

    Dealing with the behavioral and psychological symptoms of dementia (BPSD) is often complex.

  12. Capillary dysfunction: its detection and causative role in dementias and stroke

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Current neurology and neuroscience reports 2015-06-01 Clinical safety

    In acute ischemic stroke, critical hypoperfusion is a frequent cause of hypoxic tissue injury: As cerebral blood flow (CBF) falls below the ischemic threshold of 20 mL/100 mL/min, neurological symptoms develop and hypoxic tissue injury evolves within minutes or hours unless the oxygen supply is restored.

  13. Long-term exposure to fine particulate matter, residential proximity to major roads and measures of brain structure

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Stroke 2015-05-01 Hippocampus size on brain scans

    Exposure to elevated levels of PM2.5 was associated with smaller total cerebral brain volume, a marker of age-associated brain atrophy, and with higher odds of covert brain infarcts.

  14. Case-Based fMRI Analysis after Cognitive Rehabilitation in MS: A Novel Approach

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in neurology 2015-04-08 Prevention trials

    The occurrence of different and opposed response patterns after the same training indicates a risk in applying classical group statistics.

  15. Is the risk of Alzheimer's disease and dementia declining?

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Alzheimer's research & therapy 2015-03-26 Clinical safety

    At least nine recent population-based studies of dementia incidence or prevalence have shown a declining age-specific risk in the US, England, The Netherlands, Sweden, and Denmark.

  16. Cognitive impairment in patients with AIDS - prevalence and severity

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. HIV/AIDS (Auckland, N.Z.) 2015-01-29 Clinical safety

    The advent of highly active antiretroviral therapy has prolonged the life expectancy of HIV patients and decreased the number of adults who progress to AIDS and HIV-associated dementia.

  17. International variation in place of death of older people who died from dementia in 14 European and non-European countries

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of the American Medical Directors Association 2014-12-18 End-of-life care

    Place of death of older people who died from a dementia-related disease differs substantially between countries, which might point to organizational differences in end-of-life care provision.

  18. Vascular contributions to cognitive impairment and dementia including Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2014-12-12 Vascular contributions

    Scientific evidence continues to demonstrate the linkage of vascular contributions to cognitive impairment and dementia such as Alzheimer's disease.

  19. Management of chronic heart failure in the older population

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of geriatric cardiology : JGC 2014-12-01 End-of-life care

    Chronic heart failure (CHF) is the leading cause of hospitalization for those over the age of 65 and represents a significant clinical and economic burden.

  20. The need for palliative care in Ireland: a population-based estimate of palliative care using routine mortality data, inclusive of nonmalignant conditions

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of pain and symptom management 2014-11-08 End-of-life care

    Future palliative care policy decisions in Ireland must consider the rapidly aging Irish population with the accompanying increase in deaths from cancer, dementia, and neurodegenerative disease and associated palliative care need.

  21. Consensus on quality indicators to assess the organisation of palliative cancer and dementia care applicable across national healthcare systems and selected by international experts

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. BMC health services research 2014-09-17 End-of-life care

    International experts selected a set of 23 QIs for the organisation of palliative care.

  22. Tailored lighting intervention improves measures of sleep, depression, and agitation in persons with Alzheimer's disease and related dementia living in long-term care facilities

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Clinical interventions in aging 2014-09-12 Clinical safety

    A lighting intervention, tailored to increase daytime circadian stimulation, can be used to increase sleep quality and improve behavior in patients with ADRD.

  23. Cognitive impairment and memory dysfunction after a stroke diagnosis: a post-stroke memory assessment

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Neuropsychiatric disease and treatment 2014-09-09 Vascular contributions

    Cognitive impairment and memory dysfunction following stroke diagnosis are common symptoms that significantly affect the survivors' quality of life.

  24. Caregivers' male gender is associated with poor nutrient intake in AD families (NuAD-trial)

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. The journal of nutrition, health & aging 2014-07-01 Treatments

    The mean age of caregivers and AD spouses was 75.2 (SD 7.0) and 77.4 years (SD 5.6), respectively.

    Why it matters

    This study found that male caregivers were associated with poorer nutrient intake in couples where one partner has Alzheimer disease. It is about caregiver gender and nutrition, not about treating, curing or preventing Alzheimer disease.

  25. Burdensome transitions at the end of life among long-term care residents with dementia

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of the American Medical Directors Association 2014-06-07 End-of-life care

    The ongoing change in long-term care from institutional care to housing services causes major challenges to the continuity of end-of-life care.

From across this topic

10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

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