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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,676–24,700 of 27,380 studies, newest first · page 988 of 1096.

November 2002 25

  1. 2002-11-01

    Microglia as neuroprotective, immunocompetent cells of the CNS

    ✓ Peer-reviewed Inflammation and the immune system Glia

    Key finding: This viewpoint article emphasizes the fundamental interdependence of microglia and neurons and takes a look at the possibility of what could happen if microglial cells became dysfunctional as a result of aging, genetics, or epigenetics.

    Full summary, score breakdown and related studies → Original source

  2. 2002-11-01

    Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling

    ✓ Peer-reviewed Risk factors Journal of neuroscience research

    Key finding: Alterations in transcription, RNA editing, translation, protein processing, and clearance are a consistent feature of Alzheimer's disease (AD) brain. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2002-11-01

    Amyloid-beta induces Smac release via AP-1/Bim activation in cerebral endothelial cells

    ✓ Peer-reviewed Drug development The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: In addition, we demonstrated that X chromosome-linked inhibitor-of-apoptosis protein (XIAP) coimmunoprecipitated with Smac, suggesting that the two proteins bound to one another subsequent to the release of Smac from the mitochondria. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2002-11-01

    Alzheimer's disease: treatments in discovery and development

    ✓ Peer-reviewed Treatments Nature neuroscience

    Key finding: Alzheimer's disease is the single biggest unmet medical need in neurology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2002-11-01

    Molecular targeting of Alzheimer's amyloid plaques for contrast-enhanced magnetic resonance imaging

    ✓ Peer-reviewed Treatments Neurobiology of disease

    Key finding: Smart molecular probes for both diagnostic and therapeutic purposes are expected to provide significant advances in clinical medicine and biomedical research.

    Full summary, score breakdown and related studies → Original source

  6. 2002-11-01

    Scavenger receptors in neurobiology and neuropathology: their role on microglia and other cells of the nervous system

    ✓ Peer-reviewed Brain scans and imaging Glia

    Key finding: Microglia, Mato cells, astrocytes, cerebral microvascular endothelial cells, cerebral arterial smooth muscle cells, and retinal pigment epithelial cells express one or more of these SR. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2002-11-01

    Similarities between Alzheimer's disease and vascular dementia

    ✓ Peer-reviewed Vascular contributions Journal of the neurological sciences

    Key finding: These two dementia types share many common pathological, symptomatic and neurochemical features, and cholinergic treatments that have demonstrated robust, broad-ranging and long-term efficacy in AD are now being assessed for the treatment of dementia related to cerebrovascular disease (CVD).

    Full summary, score breakdown and related studies → Original source

  8. 2002-11-01

    Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma

    ✓ Peer-reviewed Hippocampus size on brain scans Nature neuroscience

    Key finding: In monozygotic twins discordant for trauma exposure, we found evidence that smaller hippocampi indeed constitute a risk factor for the development of stress-related psychopathology. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2002-11-01

    Ageing and infection

    ✓ Peer-reviewed End-of-life care The Lancet. Infectious diseases

    Key finding: Infections in the elderly are not only more frequent and more severe, but they also have distinct features with respect to clinical presentation, laboratory results, microbial epidemiology, treatment, and infection control.

    Full summary, score breakdown and related studies → Original source

  10. 2002-11-01

    Effects of cognitive training interventions with older adults: a randomized controlled trial

    ✓ Peer-reviewed Prevention trials JAMA

    Key finding: Training effects were of a magnitude equivalent to the amount of decline expected in elderly persons without dementia over 7- to 14-year intervals. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2002-11-01

    Microglia in human immunodeficiency virus-associated neurodegeneration

    ✓ Peer-reviewed Inflammation and the immune system Glia

    Key finding: Neurons are not productively infected by HIV. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2002-11-01

    Neuroanatomical distribution of CXCR4 in adult rat brain and its localization in cholinergic and dopaminergic neurons

    ✓ Peer-reviewed Inflammation and the immune system The European journal of neuroscience

    Key finding: Up to now scarce evidence has been given of the neuroanatomical distribution of chemokine receptors. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2002-11-01

    Protective effects of estrogen and selective estrogen receptor modulators in the brain

    ✓ Peer-reviewed Inflammation and the immune system Biology of reproduction

    Key finding: Here, we review the progress in this field, with a particular focus upon estrogen-induced protection from stroke-induced ischemic damage. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2002-11-01

    Neuroinflammation in Alzheimer's disease and prion disease

    ✓ Peer-reviewed Inflammation and the immune system Glia

    Key finding: In both disorders, these cerebral amyloid deposits are co-localized with a broad variety of inflammation-related proteins (complement factors, acute-phase protein, pro-inflammatory cytokines) and clusters of activated microglia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2002-11-01

    Cerebrovascular pathology and dementia in autopsied Honolulu-Asia Aging Study participants

    ✓ Peer-reviewed Brain tissue and pathology Annals of the New York Academy of Sciences

    Key finding: The decedents were long-standing participants in the Honolulu-Asia Aging Study, a prospective epidemiologic investigation of stroke, neurodegenerative diseases, and aging. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2002-11-01

    A double-blind, placebo-controlled multicentre study of memantine in mild to moderate vascular dementia (MMM500)

    ✓ Peer-reviewed Treatments International clinical psychopharmacology

    Key finding: This was a 28-week, double-blind, parallel, randomized controlled trial of memantine 20 mg daily versus placebo which was conducted in 54 centres in the UK. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2002-11-01

    [Corticobasal degeneration and progressive supranuclear palsy--biochemical marker]

    ✓ Peer-reviewed Tau biomarkers Rinsho shinkeigaku = Clinical neurology

    Key finding: However, in patients with other diseases showing neurofibrillary tangles (NFT) similar to those in AD, tau proteins in cerebrospinal fluids have not been rigorously investigated. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2002-11-01

    Cerebrospinal fluid tau and beta-amyloid 42 proteins identify Alzheimer disease in subjects with mild cognitive impairment

    ✓ Peer-reviewed Mild cognitive impairment Archives of neurology

    Key finding: Our results indicate that altered tau and Abeta42 concentrations may be detectable in subjects who are clinically diagnosed as having MCI but demonstrate the pathological changes of AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2002-11-01

    Abeta toxicity in Alzheimer's disease: globular oligomers (ADDLs) as new vaccine and drug targets

    ✓ Peer-reviewed Mild cognitive impairment Neurochemistry international

    Key finding: Over the past several years, experiments with synthetic amyloid-beta peptide (Abeta) and animal models have strongly suggested that pathogenesis of Alzheimer's disease (AD) involves soluble assemblies of Abeta peptides (Trends Neurosci. 24 (2001) 219).

    Full summary, score breakdown and related studies → Original source

  20. 2002-11-01

    Clinical correlates of selective pathology in the amygdala of patients with Parkinson's disease

    ✓ Peer-reviewed Lewy body dementia Brain : a journal of neurology

    Key finding: The amygdala exhibits significant pathological changes in Parkinson's disease, including atrophy and Lewy body (LB) formation. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2002-11-01

    Abnormality of gait as a predictor of non-Alzheimer's dementia

    ✓ Peer-reviewed Lewy body dementia The New England journal of medicine

    Key finding: The presence of neurologic gait abnormalities in elderly persons without dementia at base line is a significant predictor of the risk of development of dementia, especially non-Alzheimer's dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2002-11-01

    A pilot study of the reliability and validity of the Caregiver Activity Survey - Intellectual Disability (CAS-ID)

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of intellectual disability research : JIDR

    Key finding: The present authors provide preliminary evidence for the validity and reliability of the CAS-ID. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2002-11-01

    The dementias

    ✓ Peer-reviewed Risk factors Lancet (London, England)

    Key finding: Different forms of dementia are now distinguished-Alzheimer's disease, dementia with Lewy bodies, frontotemporal dementia, and dementia secondary to disease, such as AIDS dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2002-11-01

    The natural history of the syndrome of primary progressive freezing gait

    ✓ Peer-reviewed Digital health tools Archives of neurology

    Key finding: Thirty patients (16 male) were diagnosed as having PPFG (mean age at onset, 72.2 years; mean duration of disease, 5 years). +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2002-11-01

    Incidence and outcome of mild cognitive impairment in a population-based prospective cohort

    ✓ Peer-reviewed How common it is Neurology

    Key finding: Conventionally defined MCI has reasonable predictive value and specificity for AD.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →