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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,651–24,675 of 27,380 studies, newest first · page 987 of 1096.

December 2002 24

  1. 2002-12-05

    The Economics of Alzheimer Disease

    ✓ Peer-reviewed Risk factors Dementia and Geriatric Cognitive Disorders

    Key finding: We found that the economic costs attributable to AD care is highly variable mostly due to non-standardised methodologies and geographical variations in care patterns. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2002-12-01

    Efficacy of Donepezil on Behavioral Symptoms in Patients With Moderate to Severe Alzheimer’s Disease

    ✓ Peer-reviewed Treatments International Psychogeriatrics

    Key finding: Baseline demographics were similar between the treatment groups. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2002-12 month only

    Double blind randomised placebo controlled trial of low dose melatonin for sleep disorders in dementia

    ✓ Peer-reviewed Clinical trials International journal of geriatric psychiatry

    Key finding: Twenty-five out of 44 completed the trial. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2002-12-01

    Nursing home facility risk factors for infection and hospitalization: importance of registered nurse turnover, administration, and social factors

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society

    Key finding: The 2-year rate of infection was 1.20 episodes per 100 resident days, and the hospitalization rate for infection was 0.17 admissions per 100 resident days. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2002-12-01

    Adenosine receptors in the nervous system: pathophysiological implications

    ✓ Peer-reviewed Risk factors Progress in neurobiology

    Key finding: Peripheral side effects associated with adenosine receptor agonists limit their usefulness in therapeutics; in contrast, adenosine receptor antagonists appear to have less side effects as it is the case of the well-known non-selective antagonists theophylline (present in tea) or caffeine (abundant in coffee and tea), and their emerging beneficial actions in Parkinson's disease and Alzheimer's disease are encouraging.

    Full summary, score breakdown and related studies → Original source

  6. 2002-12-01

    Cognitive activity and incident AD in a population-based sample of older persons

    ✓ Peer-reviewed Prevention trials Neurology

    Key finding: Frequency of participation in cognitively stimulating activities appears to be associated with risk of AD and may partially explain the association of educational and occupational attainment with disease risk. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2002-12-01

    The glucagon-like peptides: a new genre in therapeutic targets for intervention in Alzheimer's disease

    ✓ Peer-reviewed Drug development Journal of Alzheimer's disease : JAD

    Key finding: GLP-1 receptors, which are coupled to the cyclic AMP second messenger pathway, are expressed throughout the brains of rodents and humans. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2002-12-01

    Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review

    ✓ Peer-reviewed Genetics Free radical research

    Key finding: Brain membranes from human apoE4 mice have greater vulnerability to Abeta(1-42)-induced oxidative stress than brain membranes from apoE2 or E3, assessed by the same indices, consistent with the notion of a coupling of the oxidative environment in AD brain and increased risk of developing this disorder. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2002-12-01

    Neuroprotection by memantine against neurodegeneration induced by beta-amyloid(1-40)

    ✓ Peer-reviewed Biomarkers Brain research

    Key finding: Memantine treated animals had significant reductions in the amount of neuronal degeneration, pyknotic nuclei, and GFAP immunostaining as compared with vehicle treated animals. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2002-12-01

    Pathophysiology of hepatic encephalopathy: a new look at ammonia

    ✓ Peer-reviewed Biomarkers Metabolic brain disease

    Key finding: Damage to astrocytes characterized by cell swelling (acute liver failure) or Alzheimer Type II astrocytosis (chronic liver failure) can be readily reproduced by acute or chronic exposure of these cells in vitro to pathophysiologically relevant concentrations of ammonia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2002-12-01

    Hippocampal deformities in schizophrenia characterized by high dimensional brain mapping

    ✓ Peer-reviewed Hippocampus size on brain scans The American journal of psychiatry

    Key finding: Schizophrenia is associated with structural deformities of the hippocampus, which suggest a disturbance of the connections between the hippocampus and the frontal cortex. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2002-12-01

    Childhood trauma associated with smaller hippocampal volume in women with major depression

    ✓ Peer-reviewed Hippocampus size on brain scans The American journal of psychiatry

    Key finding: A smaller hippocampal volume in adult women with major depressive disorder was observed exclusively in those who had a history of severe and prolonged physical and/or sexual abuse in childhood. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2002-12-01

    Heterogeneous expression of the triggering receptor expressed on myeloid cells‐2 on adult murine microglia

    ✓ Peer-reviewed TREM2 and immune genetics Journal of Neurochemistry

    Microglial activation is an early and common feature of almost all neuropathologies, including multiple sclerosis, Alzheimer's disease and mechanical injury.

    Full summary, score breakdown and related studies → Original source

  14. 2002-12-01

    Test of Grocery Shopping Skills: Discrimination of People with and without Mental Illness

    ✓ Peer-reviewed Risk factors Psychiatric Rehabilitation Skills

    Key finding: The present study examines the validity of the TOGSS by comparing performance of two groups with significant cognitive impairments i.e., individuals who have schizophrenia or bipolar disorders and meet the criteria for serious mental illness (SMI), with a normative population.

    Full summary, score breakdown and related studies → Original source

  15. 2002-12-01

    Long-term accumulation of amyloid-beta in axons following brain trauma without persistent upregulation of amyloid precursor protein genes

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neuropathology and experimental neurology

    Key finding: Here, we evaluated the effects of brain trauma on the accumulation of Abeta and expression of amyloid precursor protein (APP) genes (APP695 and APP751/ 770) over 1 yr in a non-transgenic rodent model. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2002-12-01

    The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing

    ✓ Peer-reviewed Risk genes beyond APOE The EMBO journal

    Key finding: Although Drosophila cannot synthesize cholesterol de novo, the regulatory role of fly AMPK on HMG-CoA reductase is conserved. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2002-12-01

    alpha- and beta-secretase: profound changes in Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE Biochemical and biophysical research communications

    Key finding: Only small amounts of Abeta form in normal brain; more typically this is precluded by the processing of APP by alpha-secretase. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2002-12-01

    Lens defects and age-related fiber cell degeneration in a mouse model of increased AbetaPP gene dosage in Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's The American journal of pathology

    Key finding: Currently, well-characterized Alzheimer transgenic mouse models are used to extend these findings. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2002-12-01

    Cytokines and cognition--the case for a head-to-toe inflammatory paradigm

    ✓ Peer-reviewed Risk factors Journal of the American Geriatrics Society

    Key finding: As such, there is a growing appreciation of the role of cytokine-mediated inflammatory processes in neurodegenerative diseases such as Alzheimer's disease and vascular dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2002-12-01

    Burden and well-being among caregivers: examining the distinction

    ✓ Peer-reviewed Caregiving The Gerontologist

    Key finding: The finding that perceived social support is strongly related to well-being but unrelated to burden reinforces the conceptual distinctiveness of the latter two concepts. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2002-12-01

    Mild cognitive impairment in older people

    ✓ Peer-reviewed Prevention and risk Lancet (London, England)

    Key finding: As public awareness of Alzheimer's disease increases, more people are asking for help and advice about memory problems.

    Full summary, score breakdown and related studies → Original source

  22. 2002-12-01

    Diet and risk of dementia: Does fat matter?: The Rotterdam Study

    ✓ Peer-reviewed Prevention and risk Neurology

    Key finding: High intake of total, saturated, and trans fat and cholesterol and low intake of MUFA, PUFA, n-6 PUFA, and n-3 PUFA were not associated with increased risk of dementia or its subtypes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2002-12-01

    Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation

    ✓ Peer-reviewed Genetics The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Compared with apoE3, apoE4 promotes the cerebral deposition of amyloid beta (Abeta) peptides, which are derived from the amyloid precursor protein (APP) and play a central role in AD.

    Full summary, score breakdown and related studies → Original source

  24. 2002-12-01

    Astrocytic deformity and globular structures are characteristic of the brains of patients with aceruloplasminemia

    ✓ Peer-reviewed Biomarkers Journal of neuropathology and experimental neurology

    Key finding: In order to study the neuropathological characteristics associated with oxidative stress, we scrutinized the brains of 5 patients with aceruloplasminemia histopathologically and immunohistochemically. +1 more finding

    Full summary, score breakdown and related studies → Original source

November 2002 1

  1. 2002-11-04

    Serum insulin-like growth factor I regulates brain amyloid-beta levels

    ✓ Peer-reviewed Caregiving Nature medicine

    Key finding: Levels of insulin-like growth factor I (IGF-I), a neuroprotective hormone, decrease in serum during aging, whereas amyloid-beta (Abeta), which is involved in the pathogenesis of Alzheimer disease, accumulates in the brain. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →