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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,051–24,075 of 27,380 studies, newest first · page 963 of 1096.

July 2004 9

  1. 2004-07-01

    Mild cognitive impairment, amnestic type: an epidemiologic study

    ✓ Peer-reviewed How common it is Neurology

    Key finding: In this community-based sample, 3 to 4% of nondemented persons met MCI operational criteria; despite increased risk of progressing to dementia, a substantial proportion also remained stable or reverted to normal during follow-up. +2 more findings

  2. 2004-07-01

    Pathways to dementia diagnosis: evidence for cross-ethnic differences

    ✓ Peer-reviewed Disparities Alzheimer disease and associated disorders

    Key finding: Help-seeking was most often initiated by family members or formal care providers (ie, healthcare providers or social workers), usually in outpatient primary care settings but also elsewhere (eg, social service agencies, hospitals). +1 more finding

  3. 2004-07-01

    Predicting the rate of cognitive decline in aging and early Alzheimer disease

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Percent total HSI, ventricular, and total CSF volume measures can independently predict the rate of cognitive decline and improve the predictive power of statistical models that use only clinical data. +3 more findings

  4. 2004-07-01
  5. 2004-07-01

    Nonsteroidal anti-inflammatory drugs for the prevention of Alzheimer's disease: a systematic review

    ✓ Peer-reviewed Prevention and risk Neuroepidemiology

    Key finding: Based on analysis of prospective and nonprospective studies, NSAID exposure was associated with decreased risk of Alzheimer's disease. +2 more findings

  6. 2004-07-01

    Metaanalysis of randomized trials of the efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer disease

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: All three drugs showed beneficial effects on cognitive tests, as compared with placebo. +3 more findings

  7. 2004-07-01

    Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease

    ✓ Peer-reviewed Genetics Experimental neurology

    Key finding: The abundant amyloid deposits in tg mice were in a consolidated state as revealed by strong Congo red birefringence. +3 more findings

  8. 2004-07-01

    Memory impairment, but not cerebrovascular disease, predicts progression of MCI to dementia

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Within a heterogenous group of MCI patients, including many with clinically significant CVD, baseline memory and executive performance significantly predicted likelihood to develop dementia. +4 more findings

  9. 2004-07-01

    Analysis of European mitochondrial haplogroups with Alzheimer disease risk

    ✓ Peer-reviewed Genetics Neuroscience letters

    Key finding: Males classified as haplogroup U showed an increase in risk (OR = 2.30; 95% CI, 1.03-5.11; P = 0.04) of AD relative to the most common haplogroup H, while females demonstrated a significant decrease in risk with haplogroup U (OR = 0.44 ; 95% CI, 0.24-0.80; P = 0.007). +2 more findings

June 2004 16

  1. 2004-06-30

    Cognitive dysfunction and dementia in Parkinson's disease

    ✓ Peer-reviewed Caregiving Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: It is thought to be the result of a combination of both subcortical and cortical changes. +1 more finding

  2. 2004-06-25

    HIV secreted protein Tat prevents long-term potentiation in the hippocampal CA1 region

    ✓ Peer-reviewed Disease mechanisms Brain research

    Key finding: Tat 1-72delta31-61, which lacks the neurotoxic domain of Tat, had no significant effect on LTP.

  3. 2004-06-25

    Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection

    ✓ Peer-reviewed Genetics The Journal of biological chemistry

    Key finding: We identified a total of 488 proteins co-isolated with the plaques, and we found multiple phosphorylation sites on the neurofilament intermediate chain, implicating the complexity and diversity of cellular processes involved in the plaque formation. +3 more findings

  4. 2004-06-24

    Stroke risk profile predicts white matter hyperintensity volume: the Framingham Study

    ✓ Peer-reviewed How common it is Stroke

    Key finding: FSRP and several cardiovascular risk factors were related to both WMHV measured continuously and to a categorical designation of large volumes of WMH. +2 more findings

  5. 2004-06-24

    Screening for cognitive impairment among older people in black and minority ethnic groups

    ✓ Peer-reviewed Disparities Age and ageing

    Key finding: This gives rise to a substantially higher risk of mistaken diagnosis of dementia. +1 more finding

  6. 2004-06-21

    Regional distribution of white matter hyperintensities in vascular dementia, Alzheimer's disease and healthy aging

    ✓ Peer-reviewed Cognitive tests and assessment Dementia and geriatric cognitive disorders

    Key finding: White matter hyperintensities (WMH) on MRI scans indicate lesions of the subcortical fiber system. +3 more findings

  7. 2004-06-13

    Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides

    ✓ Peer-reviewed Genetics Nature medicine

    Key finding: We have previously shown that apolipoprotein E (Apoe) promotes the formation of amyloid in brain and that astrocyte-specific expression of APOE markedly affects the deposition of amyloid-beta peptides (Abeta) in a mouse model of Alzheimer disease.

  8. 2004-06-09

    Gene regulation and DNA damage in the ageing human brain

    ✓ Peer-reviewed Disease mechanisms Nature

    Key finding: These genes play central roles in synaptic plasticity, vesicular transport and mitochondrial function. +4 more findings

  9. 2004-06-03

    Neurodegenerative disorders associated with diabetes mellitus

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of molecular medicine (Berlin, Germany)

    Key finding: More than 20 syndromes among the significant and increasing number of degenerative diseases of neuronal tissues are known to be associated with diabetes mellitus, increased insulin resistance and obesity, disturbed insulin sensitivity, and excessive or impaired insulin secretion. +1 more finding

  10. 2004-06-01

    Hsp70 Reduces α-Synuclein Aggregation and Toxicity

    ✓ Peer-reviewed Brain tissue and pathology Journal of Biological Chemistry

    Key finding: Introducing the molecular chaperone Hsp70 into the in vivo model by breeding alpha-synuclein transgenic mice with Hsp70-overexpressing mice led to a significant reduction in both the high molecular weight and detergent-insoluble alpha-synuclein species. +2 more findings

  11. 2004-06 month only

    Review of donepezil, rivastigmine, galantamine and memantine for the treatment of dementia in Alzheimer's disease in adults with Down syndrome: implications for the intellectual disability population

    ✓ Peer-reviewed Treatments International journal of geriatric psychiatry

    Key finding: The management of dementia in Alzheimer's disease has dramatically changed since the development of anti-dementia drugs. +4 more findings

  12. 2004-06-01

    Plasma homocysteine levels and risk of Alzheimer disease

    ✓ Peer-reviewed Costs and economics Neurology

    Key finding: High homocysteine levels were not associated with AD and were not related to a decrease in memory scores over time. +3 more findings

  13. 2004-06-01

    Insulin resistance syndrome in children

    ✓ Peer-reviewed Disparities The Journal of clinical endocrinology and metabolism

    Key finding: The natural history includes small for gestational age birth weight, excessive weight gains during childhood, premature pubarche, an allergic diathesis, acanthosis nigricans, striae compounded by gynecomastia, hypertriglyceridemia, hepatic steatosis, premature atherosclerosis, hypertension, polycystic ovarian syndrome, and focal glomerulonephritis appearing increasingly through adolescence into adulthood. +4 more findings

  14. 2004-06-01

    Validation of a 26-point telephone version of the Mini-Mental State Examination

    ✓ Peer-reviewed Risk factors Journal of geriatric psychiatry and neurology

    Key finding: Hearing impairment and education level did not significantly affect telephone-based performance.

  15. 2004-06-01

    Glycogen synthase kinase 3: a drug target for CNS therapies

    ✓ Peer-reviewed Drug development Journal of neurochemistry

    Key finding: The most exciting of the possibilities of GSK3 lies within the treatment of Alzheimer's disease (AD) where abnormal increases in GSK3 levels and activity have been associated with neuronal death, paired helical filament tau formation and neurite retraction as well as a decline in cognitive performance.

  16. 2004-06-01

    Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): randomised double-blind trial

    ✓ Peer-reviewed Treatments Lancet (London, England)

    Key finding: Cognition averaged 0.8 MMSE (mini-mental state examination) points better (95% CI 0.5-1.2; p<0.0001) and functionality 1.0 BADLS points better (0.5-1.6; p<0.0001) with donepezil over the first 2 years. +2 more findings

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