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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,801–24,825 of 27,380 studies, newest first · page 993 of 1096.

July 2002 12

  1. 2002-07-01

    Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain

    ✓ Peer-reviewed Risk genes beyond APOE Journal of lipid research

    Key finding: Therefore, the concentrations of cholesterol, its precursors, and its degradation products in brain homogenates of aging wild-type and beta-amyloid precursor protein transgenic mice carrying the Swedish mutation (APP23) were analyzed. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2002-07-01

    The aging brain. Changes in the neuronal insulin/insulin receptor signal transduction cascade trigger late-onset sporadic Alzheimer disease (SAD). A mini-review

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: Aging of the brain was found to be associated with a multitude of aberrancies from normal in morphological, cellular and molecular terms. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2002-07-01

    Patients with Alzheimer disease have lower levels of serum anti-amyloid peptide antibodies than healthy elderly individuals

    ✓ Peer-reviewed Risk genes beyond APOE Experimental gerontology

    Key finding: If anti-Abeta42 antibodies protect APP-transgenic mice, a model of Alzheimer's disease (AD), a high titer of anti-Abeta42 antibodies may protect humans from AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2002-07-01

    Human brain nascent polypeptide-associated complex alpha subunit is decreased in patients with Alzheimer' s disease and Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of investigative medicine : the official publication of the American Federation for Clinical Research

    Key finding: The significant decrease in alpha-NAC mRNA was shown by semiquantitative reverse transcription-polymerase chain reaction, and in parallel, the significant decrease of alpha-NAC protein, which was even more pronounced when related to either actin or neuron-specific enolase levels, was also observed in both disorders. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2002-07-01

    Down syndrome and Alzheimer disease: response to donepezil

    ✓ Peer-reviewed Down syndrome and Alzheimer's Archives of neurology

    Key finding: Acetylcholinesterase inhibitors may be helpful in reversing the symptoms of dementia during early and middle stages of cognitive decline. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2002-07-01

    Long-term persistence in use of statin therapy in elderly patients

    ✓ Peer-reviewed How common it is JAMA

    Key finding: Persistence with statin therapy in older patients declines substantially over time, with the greatest drop occurring in the first 6 months of treatment.

    Full summary, score breakdown and related studies → Original source

  7. 2002-07-01

    The prevalence of dementia in older people in an urban population of Korea: the Seoul study

    ⚠ Retracted — do not rely on it Disparities Journal of the American Geriatrics Society

    Key finding: The prevalence of dementia in older people in Seoul appears to be somewhat lower than in rural areas of Korea. +1 more finding

    Scored 24 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  8. 2002-07-01

    Does caffeine intake protect from Alzheimer's disease?

    ✓ Peer-reviewed Prevention and risk European journal of neurology

    Key finding: If caffeine intake could protect against neurodegeneration in Alzheimer's disease (AD), then higher levels of caffeine consumption in normal subjects as compared with AD patients should be detectable in the presumably long period before diagnosis when insidious pathogenic changes are taking place. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2002-07-01

    Cerebrolysin in Alzheimer's disease: a randomized, double-blind, placebo-controlled trial with a neurotrophic agent

    ✓ Peer-reviewed Treatments Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: Cerebrolysin (Cere) is a compound with neurotrophic activity. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2002-07-01

    [Clinical efficacy and safety of huperzine Alpha in treatment of mild to moderate Alzheimer disease, a placebo-controlled, double-blind, randomized trial]

    ✓ Peer-reviewed Treatments Zhonghua yi xue za zhi

    Key finding: A safe and effective medicine, huperzine Alpha remarkably improves the cognition, behavior, ADL,and mood of AD patients. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2002-07-01

    The apolipoprotein E epsilon 4 allele and decline in different cognitive systems during a 6-year period

    ✓ Peer-reviewed Genetics Archives of neurology

    Key finding: The presence of epsilon 4 was associated with risk of developing AD on follow-up (relative risk, 1.92; 95% confidence interval, 1.27-2.89). +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2002-07-01

    Differential distribution of laminins in Alzheimer disease and normal human brain tissue

    ✓ Peer-reviewed Biomarkers Journal of neuroscience research

    Key finding: We found that alpha 1 laminin was heavily over-expressed in Alzheimer disease frontal cortex, and localized in reactive astrocytes of the grey and white matter, and as punctate deposits in the senile placques of the Alzheimer brain tissue. +4 more findings

    Full summary, score breakdown and related studies → Original source

June 2002 13

  1. 2002-06-25

    Phases of Aβ-deposition in the human brain and its relevance for the development of AD

    ✓ Peer-reviewed Brain tissue and pathology Neurology

    Key finding: In the first of five phases in the evolution of beta-amyloidosis Abeta deposits are found exclusively in the neocortex. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2002-06-21

    Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

    ✓ Peer-reviewed TREM2 and immune genetics American journal of human genetics

    Key finding: Elsewhere, we have identified PLOSL mutations in TYROBP (DAP12), which codes for a membrane receptor component in natural-killer and myeloid cells, and also have identified genetic heterogeneity in PLOSL, with some patients carrying no mutations in TYROBP. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2002-06-18

    Clinical features and molecular bases of neuroacanthocytosis

    ✓ Peer-reviewed Clinical safety Journal of molecular medicine (Berlin, Germany)

    Key finding: Acanthocytosis is found to be associated with at least three hereditary neurological disorders that are generally referred to as neuroacanthocytosis. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2002-06 month only

    Inappropriate medication prescribing in residential care/assisted living facilities

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society

    Key finding: The majority of RC/AL patients were taking five or more medications; 16.0% of these patients were receiving IPMs. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2002-06-01

    Intraneuronal Abeta42 accumulation in Down syndrome brain

    ✓ Peer-reviewed Down syndrome and Alzheimer's Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis

    Key finding: Abeta40 antibodies did not detect significant intracellular Abeta, but older cases showed Abeta40 IR in mature plaques. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2002-06-01

    Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress

    ✓ Peer-reviewed Disease mechanisms Free radical biology & medicine

    Key finding: Recent research suggests that these two observations may be linked by A(beta)-induced oxidative stress in AD brain.

    Full summary, score breakdown and related studies → Original source

  7. 2002-06-01

    Dendritic spine pathology: cause or consequence of neurological disorders?

    ✓ Peer-reviewed Prevention and risk Brain research. Brain research reviews

    Key finding: Similarly, spine distributions are altered in the developing brain following malnutrition, alcohol or toxin exposure, infection, and in a large number of genetic disorders that result in mental retardation, such as Down's and fragile-X syndromes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2002-06-01

    White matter damage in Alzheimer's disease assessed in vivo using diffusion tensor magnetic resonance imaging

    ✓ Peer-reviewed Brain scans and imaging Journal of neurology, neurosurgery, and psychiatry

    Key finding: White matter changes in patients with Alzheimer's disease are likely to be secondary to wallerian degeneration of fibre tracts due to neuronal loss in cortical associative areas. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2002-06-01

    Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease

    ✓ Peer-reviewed Tau biomarkers Archives of neurology

    Key finding: These results imply that individuals with MCI have increased brain oxidative damage before the onset of symptomatic dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2002-06-01

    Amyloid beta-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD

    Key finding: Alzheimer's disease (AD) brain is characterized by excess deposition of amyloid beta-peptide (Abeta), particularly the 42-amino acid peptide [Abeta(1-42)] and by extensive oxidative stress. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2002-06-01

    Signature tau neuropathology in gray and white matter of corticobasal degeneration

    ✓ Peer-reviewed Disease mechanisms The American journal of pathology

    Key finding: The insoluble tau pathology in gray and white matter showed overlapping but distinct phosphorylated epitopes suggesting cell-type and subcellular localization (ie, cell bodies versus cell processes)-specific differences in tau phosphorylation.

    Full summary, score breakdown and related studies → Original source

  12. 2002-06-01

    Argyrophilic grain disease is a sporadic 4-repeat tauopathy

    ✓ Peer-reviewed Disease mechanisms Journal of neuropathology and experimental neurology

    Key finding: Immunohistochemistry with monoclonal antibodies specific to tau isoforms with four (4R) or three (3R) repeats in the microtubule-binding domain showed immunostaining of grains with 4R, but not 3R, tau antibodies, suggesting that AGD was a 4R tauopathy. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2002-06-01

    Cerebral amyloid angiopathy and cognitive function: the HAAS autopsy study

    ✓ Peer-reviewed Brain tissue and pathology Neurology

    Key finding: Starting in 1991, participants were assessed with the Cognitive Abilities Screening Instrument (CASI) and diagnosed with dementia (including subtype) based on published criteria. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →