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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,176–12,200 of 27,380 studies, newest first · page 488 of 1096.

December 2019 25

  1. 2019-12-24

    Alzheimer's Disease - Why We Need Early Diagnosis

    ✓ Peer-reviewed Prevention and risk Degenerative neurological and neuromuscular disease

    Key finding: It examines how Alzheimer's disease diagnosis rates can be improved, the implications of an early diagnosis for the individual, carer and society, and the importance of risk reduction to prevent or delay progression. +4 more findings

  2. 2019-12-23

    Correlation Between Donepezil and QTc Prolongation and Torsades de Pointes: A Very Rare Phenomenon

    ✓ Peer-reviewed Treatments Cureus

    Key finding: Patients demonstrated associated atrioventricular (AV) block or ventricular premature contractions (VPC) or atrial fibrillation (AF) prior to developing torsades de pointes (TdP). +1 more finding

  3. 2019-12-23

    Effect of Clostridium butyricum against Microglia-Mediated Neuroinflammation in Alzheimer's Disease via Regulating Gut Microbiota and Metabolites Butyrate

    ✓ Peer-reviewed Disease mechanisms Molecular nutrition & food research

    Key finding: Scope Recent evidences demonstrate that abnormal gut microbiota (GM) might be involved in the pathogenesis of Alzheimer's disease (AD). +2 more findings

  4. 2019-12-23

    What’s Happening at Home

    ✓ Peer-reviewed Health systems and care delivery Medical Care

    Key finding: Overall, 5% of the study population (n=161,801) received 2+ months of HCC visits; of these, 46% also received 2+ HBMC visits (n=73,638) while 54% received only skilled home health (n=88,163 HCC but no HBMC). +3 more findings

  5. 2019-12-23

    A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC-derived microglia

    ✓ Peer-reviewed TREM2 and immune genetics FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    Key finding: Microglia, the resident immune cell of the brain, express TREM2, and microglial responses are implicated in dementia pathways. +3 more findings

  6. 2019-12-23

    High Blood Pressure and Cardiovascular Disease

    ✓ Peer-reviewed Prevention and risk Hypertension (Dallas, Tex. : 1979)

    Key finding: Fragmented investigation has masked the overall picture for causes of cardiovascular disease (CVD). +3 more findings

  7. 2019-12-20

    Is tau in the absence of amyloid on the Alzheimer's continuum?: A study of discordant PET positivity

    ✓ Peer-reviewed Disease mechanisms Brain communications

    Key finding: Given that cognitive performance in the A-/T+ group was poorer than in individuals without either pathology, our results suggest that medial temporal lobe tau without cortical amyloid beta may reflect an early stage on the Alzheimer's pathological continuum.

  8. 2019-12-20

    β-Amyloid PET and neuropathology in dementia with Lewy bodies

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Lower PiB uptake accurately distinguishes cases with LBD from cases with AD or mixed pathology, correlating with the Thal Aβ phase. +1 more finding

  9. 2019-12-19

    Prognostic Awareness, Disease and Palliative Understanding Among Caregivers of Patients With Dementia

    ✓ Peer-reviewed End-of-life care The American journal of hospice & palliative care

    Key finding: Prognostic discussions between caregivers of PwD and the PwD's physicians may be occurring more often; however, a high percentage of caregivers report a poor understanding about the terminal nature of dementia and the role of PC. +2 more findings

  10. 2019-12-19

    Ethical concerns with the use of intelligent assistive technology: findings from a qualitative study with professional stakeholders

    ✓ Peer-reviewed Digital health tools BMC medical ethics

    Key finding: Our findings indicate a general agreement among professional stakeholders on the ethical promises and challenges raised by the use of IATs among older and disabled users. +3 more findings

  11. 2019-12-18

    CSF angiogenin levels in amyotrophic lateral Sclerosis-Frontotemporal dementia spectrum

    ✓ Peer-reviewed Tau biomarkers Amyotrophic lateral sclerosis & frontotemporal degeneration

    Key finding: ANG levels didn't differ significantly between cases and controls. +2 more findings

  12. 2019-12-18

    Genetics of Alzheimer's disease: where we are, and where we are going

    ✓ Peer-reviewed Genetics Current opinion in neurobiology

    Key finding: Alzheimer's disease (AD) has a very strong genetic component, whose characterization has become an essential part of efforts to understand the pathophysiological processes of the disease. +4 more findings

  13. 2019-12-18

    Association of brain amyloidosis with the incidence and frequency of neuropsychiatric symptoms in ADNI: a multisite observational cohort study

    ✓ Peer-reviewed Long-term cohort studies BMJ open

    Key finding: 275 cognitively normal controls (NC), 100 subjective memory complaint (SMC), 559 mild cognitive impairment (MCI) and 143 Alzheimer's disease dementia subjects from the Alzheimer's Disease Neuroimaging Initiative received ( 18 F)-florbetapir positron emission tomography (PET) scans. +3 more findings

  14. 2019-12-18

    A Deep Learning Approach for Automated Diagnosis and Multi-Class Classification of Alzheimer's Disease Stages Using Resting-State fMRI and Residual Neural Networks

    ✓ Peer-reviewed Long-term cohort studies Journal of medical systems

    Key finding: Although, research on AD has increased in recent years, however, the complexity associated with brain structure and functions makes the early diagnosis of this disease a challenging task. +3 more findings

  15. 2019-12-18

    A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort

    ✓ Peer-reviewed Digital health tools Alzheimer's & dementia (New York, N. Y.)

    Key finding: This study showed that plasma metabolites have the potential to match the AUC of well-established AD CSF biomarkers in a relatively small cohort. +3 more findings

  16. 2019-12-17

    Cognitive correlates of cerebellar resting-state functional connectivity in Parkinson disease

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: The participants with PD had significantly weaker FC between the vermis and peristriate visual association cortex compared to controls, and the strength of this FC correlated with visuospatial function and global cognition. +4 more findings

  17. 2019-12-17

    Advanced Glycation End Products (AGEs) May Be a Striking Link Between Modern Diet and Health

    ✓ Peer-reviewed Disease mechanisms Biomolecules

    Key finding: Cooking at high temperature results in various food products having high levels of AGEs. +2 more findings

  18. 2019-12-17

    Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice

    ✓ Peer-reviewed Tau biomarkers Alzheimer's research & therapy

    Key finding: Alzheimer disease (AD) is characterized by the accumulation of beta-amyloid (Aβ) plaques and neurofibrillary tangles composed of hyperphosphorylated tau, which together lead to neurodegeneration and cognitive decline. +3 more findings

  19. 2019-12-17
  20. 2019-12-17

    Hippocampal Volume Loss, Brain Amyloid Accumulation, and APOE Status in Cognitively Intact Elderly Subjects

    ✓ Peer-reviewed Biomarkers Neuro-degenerative diseases

    Key finding: The progressive decrement of neuropsychological performance is associated with HVL long before the emergence of clinically overt symptoms. +3 more findings

  21. 2019-12-16

    Survival time tool to guide care planning in people with dementia

    ✓ Peer-reviewed End-of-life care Neurology

    Key finding: Three-year survival after dementia diagnosis can be predicted with good accuracy.

  22. 2019-12-16

    Effects of Transcranial Direct Current Stimulation Paired With Cognitive Training on Functional Connectivity of the Working Memory Network in Older Adults

    ✓ Peer-reviewed Prevention trials Frontiers in aging neuroscience

    Key finding: These results suggest pairing tDCS with cognitive training enhances functional connectivity and working memory performance in older adults, and thus may hold promise as a method for remediating age-related cognitive decline. +2 more findings

  23. 2019-12-16

    A multi-model deep convolutional neural network for automatic hippocampus segmentation and classification in Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment NeuroImage

    Key finding: Additionally, the extraction of these features is independent of the classification model, which could result in sub-optimal performance. +1 more finding

  24. 2019-12-16

    Adaptation of the Clinical Dementia Rating Scale for adults with Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of neurodevelopmental disorders

    Key finding: The modified questionnaire and interview instruments capture a range of impairment in DS adults, including subthreshold symptomatology, and the instruments provide complementary information relevant to the ascertainment of dementia in DS. +1 more finding

  25. 2019-12-16

    Benchmarking machine learning models for late-onset alzheimer's disease prediction from genomic data

    ✓ Peer-reviewed Digital health tools BMC bioinformatics

    Key finding: Machine learning models are promising alternatives for estimating the genetic risk of LOAD. +2 more findings

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