Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 27,176–27,200 of 27,380 studies, newest first · page 1088 of 1096.
February 1988 2
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1988-02-01
The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex
55/100 ✓ Peer-reviewed Brain tissue and pathology Science (New York, N.Y.)
Key finding: This dementia is due partially or wholly to a direct effect of the virus on the brain rather than to opportunistic infection, but its pathogenesis is not well understood. +3 more findings
Full summary, score breakdown and related studies → Original source
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1988-02-01
Patterns of discourse cohesion and coherence in Alzheimer's disease
36/100 ✓ Peer-reviewed Digital health tools The Journal of speech and hearing disorders
Key finding: Compared to the well elderly, SDAT patients used significantly more words and conversational turns. +4 more findings
Full summary, score breakdown and related studies → Original source
January 1988 6
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1988-01-01
A Chinese version of the Mini-Mental State Examination; impact of illiteracy in a Shanghai dementia survey
40/100 ✓ Peer-reviewed Risk factors Journal of clinical epidemiology
Key finding: However, in the 26.7% who had not gone to school, there was a significant increase in low scores on the mental status test as well as a different error pattern, reflecting the lack of formal education.
Full summary, score breakdown and related studies → Original source
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1988-01-01
Behavioral disturbance in dementia of the Alzheimer's type
45/100 ✓ Peer-reviewed Clinical safety Journal of the American Geriatrics Society
Key finding: Behavioral problems are thought to be pervasive and devastating to patients with dementia of the Alzheimer's type and their families. +3 more findings
Full summary, score breakdown and related studies → Original source
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1988 no date recorded — placed by publication year
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1988-01-01
Expression of the histocompatibility glycoprotein HLA-DR in neurological disease
49/100 ✓ Peer-reviewed Inflammation and the immune system Acta neuropathologica
Key finding: Reactive astrocytes, also present in these conditions, were established as a population distinct from the HLA-DR positive microglia by double immunostaining for glial fibrillary acidic protein and HLA-DR. +3 more findings
Full summary, score breakdown and related studies → Original source
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1988-01-01
Serum IgG brain reactive antibodies in Alzheimer disease and Down syndrome
34/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Alzheimer disease and associated disorders
Key finding: Circulating BRAs were found in 57% of patients with AD, 81% of patients with DS, and 30% of normal controls. +4 more findings
Full summary, score breakdown and related studies → Original source
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1988-01-01
Neurometrics: computer-assisted differential diagnosis of brain dysfunctions
49/100 ✓ Peer-reviewed Getting a diagnosis Science (New York, N.Y.)
Key finding: The magnitude of the deviations increases with clinical severity. +4 more findings
Full summary, score breakdown and related studies → Original source
December 1987 1
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1987-12-01
Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients
36/100 ✓ Peer-reviewed Risk factors Proceedings of the National Academy of Sciences of the United States of America
Key finding: Diabetes-associated peptide contains 37 amino acids and is 46% identical to the sequences of rat and human calcitonin gene-related peptide, indicating that these peptides are related in evolution. +4 more findings
Full summary, score breakdown and related studies → Original source
November 1987 1
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1987-11-01
The prevalence of dementia: a quantitative integration of the literature
48/100 ✓ Peer-reviewed How common it is Acta psychiatrica Scandinavica
Key finding: Data from studies of dementia prevalence between 1945 to 1985 were analyzed statistically. +4 more findings
Full summary, score breakdown and related studies → Original source
October 1987 1
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1987-10-01
Senile dementia of the Binswanger type. A vascular form of dementia in the elderly
41/100 ✓ Peer-reviewed Digital health tools JAMA
Key finding: Computed tomography and magnetic resonance imaging in the elderly have demonstrated the common occurrence of deep white-matter lesions in the aging brain. +1 more finding
Full summary, score breakdown and related studies → Original source
September 1987 2
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1987-09-01
Chronic stress and immunity in family caregivers of Alzheimerʼs disease victims
36/100 ✓ Peer-reviewed Prevention and risk Psychosomatic Medicine
Key finding: Although acute stress has been associated with transient immunosuppression, little is known about the immunologic consequences of chronic stress in humans. +4 more findings
Full summary, score breakdown and related studies → Original source
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1987-09-01
The genetic defect in familial Alzheimer's disease is not tightly linked to the amyloid beta-protein gene
41/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Nature
Key finding: Recent molecular genetic evidence has indicated that AP is encoded as part of a larger protein by a gene on chromosome 21 (refs 5-7). +1 more finding
Full summary, score breakdown and related studies → Original source
August 1987 6
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1987-08-01
Assessment of visual impairment in patients with Alzheimer's disease
41/100 ✓ Peer-reviewed Risk factors American journal of ophthalmology
Key finding: We examined five patients with Alzheimer's disease who complained of poor vision. +4 more findings
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1987-08-01
Adverse drug reactions associated with global cognitive impairment in elderly persons
48/100 ✓ Peer-reviewed Drug development Annals of internal medicine
Key finding: Thirty-five patients with adverse drug reaction were identified among more than 300 patients evaluated for cognitive impairment and compared with patients without adverse drug reaction. +3 more findings
Full summary, score breakdown and related studies → Original source
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1987-08-01
The Modified Mini-Mental State (3MS) examination.
49/100 ✓ Peer-reviewed Cognitive tests and assessment The Journal of clinical psychiatry
Key finding: Greater sensitivities of the 3MS over the MMS are demonstrated with the pentagon item drawn by 249 patients.
Full summary, score breakdown and related studies → Original source
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1987-08-01
Hereditary cerebral hemorrhage with amyloidosis in patients of Dutch origin is related to Alzheimer disease
44/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Proceedings of the National Academy of Sciences of the United States of America
Key finding: Immunohistochemical studies of five patients revealed that the vascular amyloid deposits reacted intensely with an antiserum raised against a synthetic peptide homologous to the Alzheimer disease-related beta-protein. +1 more finding
Full summary, score breakdown and related studies → Original source
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1987-08-01
MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging
59/100 ✓ Peer-reviewed Risk factors AJR. American journal of roentgenology
Key finding: A significant number of Alzheimer patients exhibited a more extensive smooth "halo" of periventricular hyperintensity when compared with controls (p = .024).
Full summary, score breakdown and related studies → Original source
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1987-08-01
Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR
49/100 ✓ Peer-reviewed Biomarkers Neuroscience letters
Key finding: Double immunostaining with antibodies to glial fibrillary acidic protein (GFAP) showed that the HLA-DR-positive cells were different from the reactive astrocytes although the occasional positively staining giant astrocyte was also seen.
Full summary, score breakdown and related studies → Original source
July 1987 2
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1987-07-01
Senile dementia of the Alzheimer's type: an important risk factor for serious falls
59/100 ✓ Peer-reviewed Clinical safety Journal of gerontology
Key finding: Falls occurred in 36% of SDAT individuals versus 11% of controls. +3 more findings
Full summary, score breakdown and related studies → Original source
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1987-07-01
Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin
50/100 ✓ Peer-reviewed How common it is Science (New York, N.Y.)
Key finding: The decline in the high incidence of amyotrophic lateral sclerosis, parkinsonism, and Alzheimer-type dementia among the Chamorro population of the western Pacific islands of Guam and Rota, coupled with the absence of demonstrable viral and hereditable factors in this disease, suggests the gradual disappearance of an environmental factor selectively associated with this culture. +1 more finding
Full summary, score breakdown and related studies → Original source
June 1987 1
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1987-06-01
Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides
45/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Proceedings of the National Academy of Sciences of the United States of America
Key finding: RNA gel blots revealed that a 3.3-kilobase mRNA species was present in the brains of individuals with Alzheimer disease, with Down syndrome, or with no apparent neurological disorders. +1 more finding
Full summary, score breakdown and related studies → Original source
May 1987 3
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1987-05-01
Behavioral symptoms in Alzheimer's disease: phenomenology and treatment
40/100 ✓ Peer-reviewed Clinical safety PubMed
Key finding: Thirty-three (58%) patients had significant behavioral symptomatology (most commonly delusions, nonspecific agitation, and diurnal rhythm disturbances).
Full summary, score breakdown and related studies → Original source
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1987-05-01
Presence of both odor identification and detection deficits in Alzheimer's disease
36/100 ✓ Peer-reviewed Prevention and risk Brain research bulletin
Key finding: Recent studies of Alzheimer's disease patients have demonstrated (a) marked structural and biochemical alterations in brain regions associated with olfactory function (including the olfactory bulb and entorhinal cortex) and (b) decrements in the ability to identify odorants. +2 more findings
Full summary, score breakdown and related studies → Original source
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1987-05-01
Short Portable Mental Status Questionnaire as a screening test for dementia and delirium among the elderly
40/100 ✓ Peer-reviewed Clinical safety Journal of the American Geriatrics Society
Key finding: Using the cut-off point (number of errors accepted) of three errors, the sensitivity of the test was 86.2% and the specificity 99.0% among medical inpatients. +4 more findings
Full summary, score breakdown and related studies → Original source
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