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Frequency and characteristics of anxiety among patients with Alzheimer's disease and related dementias
Porter VR, Buxton WG, Fairbanks LA, Strickland T, O'Connor SM, Rosenberg-Thompson S, Cummings JL.. The Journal of neuropsychiatry and clinical neurosciences, 2003-01-01
Topic: Amyloid, tau and blood-test diagnosis
The purpose of this study was to assess the cross-sectional prevalence and characteristics of anxiety among patients with Alzheimer's disease (AD), as compared with patients with frontotemporal dementia (FTD), patients with vascular dementia (VaD), and normal control subjects. The authors used the anxiety subscale of the Neuropsychiatric Inventory (NPI), an instrument with established reliability and validity, to compare patients. Patients were identified in a query of the UCLA Alzheimer's Disease Center database and included 115 patients with probable AD, 43 patients with VaD, 33 patients with FTD, and 40 normal, elderly control subjects.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Porter, V. R., Buxton, W. G., Fairbanks, L. A., Strickland, T., O'Connor, S. M., Rosenberg-Thompson, S., et al. (2003). Frequency and characteristics of anxiety among patients with Alzheimer's disease and related dementias. The Journal of neuropsychiatry and clinical neurosciences. https://doi.org/10.1176/jnp.15.2.180
Vancouver
Porter VR, Buxton WG, Fairbanks LA, Strickland T, O'Connor SM, Rosenberg-Thompson S, et al. Frequency and characteristics of anxiety among patients with Alzheimer's disease and related dementias. The Journal of neuropsychiatry and clinical neurosciences. 2003. doi:10.1176/jnp.15.2.180. PMID: 12724459.
BibTeX
@article{porter2003-12724459,
author = {Porter, V. R. and Buxton, W. G. and Fairbanks, L. A. and Strickland, T. and O'Connor, S. M. and Rosenberg-Thompson, S. and Cummings, J. L.},
title = {{Frequency and characteristics of anxiety among patients with Alzheimer's disease and related dementias}},
journal = {The Journal of neuropsychiatry and clinical neurosciences},
year = {2003},
doi = {10.1176/jnp.15.2.180},
pmid = {12724459},
url = {https://doi.org/10.1176/jnp.15.2.180}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
Key findings
- The authors used the anxiety subscale of the Neuropsychiatric Inventory (NPI), an instrument with established reliability and validity, to compare patients.
- Patients were identified in a query of the UCLA Alzheimer's Disease Center database and included 115 patients with probable AD, 43 patients with VaD, 33 patients with FTD, and 40 normal, elderly control subjects.
- Descriptive statistics were generated, and partial correlations, controlling for Mini-Mental State Examination (MMSE) score, were performed between the anxiety subscale and other behavioral features as measured by the NPI and the Functional Activities Questionnaire (FAQ).
- Relationships between cognitive status (as indicated by MMSE score) and anxiety were explored.
Why it matters
This cross-sectional study compared anxiety in patients with Alzheimer's disease, frontotemporal dementia, vascular dementia, and normal controls using the Neuropsychiatric Inventory anxiety subscale. It describes how common and what anxiety looks like in these patients but does not test any treatment, cure, or prevention.
Study details
- Study designcross-sectional
- Participants115
- Evidence strengthLow
How this study scored 52/100
Published in a peer-reviewed journal, and it is a snapshot of people at one point in time. Scored zero for effect reported and randomized / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (The Journal of neuropsychiatry and clinical neurosciences) |
| Journal's citation record | 2 / 4 | Journal of Neuropsychiatry: journal h-index 155 (OpenAlex, 2026-10-29) |
| Study design | 4 / 12 | A snapshot of people at one point in time |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2003 — older than 20 years, still counted |
| Sample size | 2 / 4 | 115 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 175 times (OpenAlex, 2026-10-10) |
| Citations per year | 2 / 5 | 7.0 citations a year over 25 year(s) since 2003 |
| Impact for its field and year | 3 / 6 | Cited 3.3× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 6 other studies in this library |
| Still being cited | 1 / 4 | Cited 13 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Jeffrey L. Cummings: h-index 175 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | University of California, Los Angeles: institution h-index 1,923 (OpenAlex) |
| Multicenter collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 12724459) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 52 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1176/jnp.15.2.180
- PubMed: 12724459
- Original source →
- Free full text: Journal of Neuropsychiatry →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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