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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 27,126–27,150 of 27,380 studies, newest first · page 1086 of 1096.

January 1989 1

  1. 1989-01-01

    Astrocytic pathology of methionine sulfoximine-induced encephalopathy

    ✓ Peer-reviewed Biomarkers Acta neuropathologica

    Key finding: These results indicate certain regionalizations in the roles of astrocytes and oligodendrocytes in glutamate and ammonia metabolisms.

    Full summary, score breakdown and related studies → Original source

December 1988 5

  1. 1988-12-01

    What are the psychiatric manifestations of vitamin B12 deficiency?

    ✓ Peer-reviewed Clinical safety Journal of the American Geriatrics Society

    Key finding: Psychiatric symptoms attributable to vitamin B12 deficiency have been described for decades. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1988-12-01

    Motor vehicle crashes in dementia of the Alzheimer type

    ✓ Peer-reviewed Clinical safety Annals of neurology

    Key finding: The occurrence of crashes was not significantly correlated with dementia severity or with disease duration. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 1988-12-01

    The amyloid percursor protein of Alzheimer disease is expressed as a 130 kDa polypeptide in various cultured cell types

    ✓ Peer-reviewed Down syndrome and Alzheimer's FEBS letters

    Key finding: Sequential extractions of cells with buffer and with Triton X-100 indicate that APP-130 is extractable with nonionic detergents at high ionic strength, whereas 228 kDa APP is a cystolic component. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 1988-12-01

    Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain

    ✓ Peer-reviewed Down syndrome and Alzheimer's Proceedings of the National Academy of Sciences of the United States of America

    Key finding: We found that gene expression for PrP and the beta-protein precursor (beta-PP) is regulated in developing hamster brain.

    Full summary, score breakdown and related studies → Original source

  5. 1988-12-01

    Language functions in Huntington's disease

    ✓ Peer-reviewed Digital health tools Brain : a journal of neurology

    Key finding: There was, however, a marked impairment in visual confrontation naming, with a significant rise in naming error rate as the disease progressed in severity. +2 more findings

    Full summary, score breakdown and related studies → Original source

November 1988 2

  1. 1988-11-01

    Hearing impairment as a predictor of cognitive decline in dementia

    ✓ Peer-reviewed Risk factors Journal of the American Geriatrics Society

    Key finding: Further division of subject by diagnosis showed that only in the Alzheimer's group did hearing impairment predict more rapid cognitive decline at follow-up.

    Full summary, score breakdown and related studies → Original source

  2. 1988-11-01

    Mapping of the gene encoding the beta-amyloid precursor protein and its relationship to the Down syndrome region of chromosome 21

    ✓ Peer-reviewed Down syndrome and Alzheimer's Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Linkage studies strongly suggest that the beta-amyloid precursor protein and the product corresponding to familial Alzheimer disease are from two genes, or at least that several million base pairs of DNA separate the markers. +1 more finding

    Full summary, score breakdown and related studies → Original source

October 1988 7

  1. 1988-10-01

    Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide

    ✓ Peer-reviewed Disease mechanisms Nature

    Key finding: From the data reported in this paper, we now suggest that the neuronal deficits associated with HIV may not be entirely a result of infectivity, but that gp120 shed from HIV could directly produce the neuropathology as a result of its interference with endogenous neurotrophic substances. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 1988-10-01

    Quantitative NMR measurements of hippocampal atrophy in Alzheimer's disease

    ✓ Peer-reviewed Hippocampus size on brain scans Magnetic resonance in medicine

    Key finding: The hippocampal volume (normalized relative to the size of the lenticular nucleus) was reduced by 40% in the AD group compared to the controls, with no overlap between the two groups. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1988-10-01

    Diffuse Lewy body disease and progressive dementia

    ✓ Peer-reviewed Clinical safety Neurology

    Key finding: We suggest that DLBD may be another specific cause of progressive dementia.

    Full summary, score breakdown and related studies → Original source

  4. 1988-10-01

    Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Since the gene on chromosome 21 encoding the beta AP precursor (beta APP) is not known to be altered in AD, transcriptional or posttranslational changes may underlie accelerated beta AP deposition. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1988-10-01

    Human ETS2 gene on chromosome 21 is not rearranged in Alzheimer disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Proceedings of the National Academy of Sciences of the United States of America

    Key finding: The human ETS2 gene, a member of the ETS gene family, with sequence homology with the retroviral ets sequence of the avian erythroblastosis retrovirus E26 is located on chromosome 21. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1988-10-01

    Long-term care of the elderly. A descriptive study of 3600 institutionalized patients in the county of Västerbotten, Sweden

    ✓ Peer-reviewed Digital health tools Comprehensive gerontology. Section A, Clinical and laboratory sciences

    Key finding: The probands' motoric functions, vision, hearing, speech, prevalence of behavioral disturbances and psychiatric symptoms, work load and use of psychoactive drugs were also investigated with special emphasis on the differences between the demented and the non-demented. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1988-10-01

    Glial fibrillary acidic protein immunohistochemical study of Alzheimer I & II astrogliosis in Wilson's disease

    ✓ Peer-reviewed Biomarkers Acta neurologica Scandinavica

    Key finding: This study compared the relationships of the development of both Alzheimer I & II cells to reactive astrogliosis and also their distributional patterns in the demyelinated and non-demyelinated lesions in 6 cases of Wilson's disease by the use of PAP immunohistochemical technique for glial fibrillary acidic protein (GFAP). +4 more findings

    Full summary, score breakdown and related studies → Original source

September 1988 2

  1. 1988-09-01

    Comparing the Areas under Two or More Correlated Receiver Operating Characteristic Curves: A Nonparametric Approach

    ✓ Peer-reviewed Cognitive tests and assessment Biometrics

    When a test is based on an observed variable that lies on a continuous or graded scale, an assessment of the overall value of the test can be made through the use of a receiver operating characteristic (ROC) curve.

    Full summary, score breakdown and related studies → Original source

  2. 1988-09-01

    Presence of T-cytotoxic suppressor and leucocyte common antigen positive cells in Alzheimer's disease brain tissue

    ✓ Peer-reviewed Inflammation and the immune system Neuroscience letters

    Key finding: Leucocytes and reactive microglia strongly expressed LCA, as well as the class II major histocompatibility complex (MCH) glycoprotein HLA-DR, but astrocytes stained negatively. +3 more findings

    Full summary, score breakdown and related studies → Original source

August 1988 7

  1. 1988-08-01

    Mechanisms of lower oesophageal sphincter incompetence in patients with symptomatic gastrooesophageal reflux

    ✓ Peer-reviewed Brain scans and imaging Gut

    Key finding: Visually impaired individuals were more likely to develop incident dementia, with a progressively greater risk among those with worse visual acuity. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1988-08-01

    Olfactory dysfunction in parkinsonism: a general deficit unrelated to neurologic signs, disease stage, or disease duration

    ✓ Peer-reviewed Prevention and risk Neurology

    Key finding: To explore the nature of the olfactory dysfunction associated with Parkinson's disease (PD), 81 PD patients who scored well on a cognitive screening test were administered the 40-odorant University of Pennsylvania Smell Identification Test; 38 were additionally given a forced-choice phenylethyl alcohol odor detection threshold test. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 1988-08-01

    Microtubule-associated polypeptides tau are altered in Alzheimer paired helical filaments

    ✓ Peer-reviewed Drug development Brain research

    Key finding: Pretreatment with alkaline phosphatase had no effect on the immunostaining. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1988-08-01

    Comparative mapping of DNA markers from the familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17

    ✓ Peer-reviewed Down syndrome and Alzheimer's Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Conservation of the linkage relationships of markers in the FAD region suggests that the murine homologue of the FAD locus probably maps to chromosome 16 and that detailed comparison of the corresponding region in both species could facilitate identification of the primary defect in this disorder.

    Full summary, score breakdown and related studies → Original source

  5. 1988-08-01

    Reexpression of a developmentally regulated antigen in Down syndrome and Alzheimer disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Proceedings of the National Academy of Sciences of the United States of America

    Key finding: ALZ-50 is a monoclonal antibody that recognizes a protein of apparent molecular mass 68 kilodaltons (A68). +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1988-08-01

    NIH conference. Alzheimer disease: clinical and biological heterogeneity

    ✓ Peer-reviewed Down syndrome and Alzheimer's Annals of internal medicine

    Key finding: The presence of considerable intersubject and intrasubject heterogeneity suggests that subtypes of the disease exist.

    Full summary, score breakdown and related studies → Original source

  7. 1988-08-01

    Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: We found similar, but less extensive, pathology in the substantia nigra of six of nine cases of dementia of the Alzheimer type (DAT) but in only one of 11 age-matched nonneurologic cases. +2 more findings

    Full summary, score breakdown and related studies → Original source

July 1988 1

  1. 1988-07-01

    Clinically diagnosed Alzheimer's disease: autopsy results in 150 cases

    ✓ Peer-reviewed Vascular contributions Annals of neurology

    Key finding: We conclude that (1) the many physicians who diagnosed these cases did so highly accurately; (2) degenerative changes in the substantia nigra were more common in patients with AD than has been reported for the general aged population; (3) amyloid angiopathy was a constant accompaniment of AD, although its severity varied widely; (4) vascular dementia was rarely clinically misdiagnosed as AD; (5) neuropathological findings were insufficient to account for the clinical syndrome of dementia in less than 2% of cases; (6) the histological criteria established by the National Institutes of Health/American Association of Retired Persons Workshop on the Diagnosis of Alzheimer's Disease worked well in assessing this large series.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →