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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,376–23,400 of 27,380 studies, newest first · page 936 of 1096.

December 2005 25

  1. 2005-12-01

    The effect of body mass index on global brain volume in middle-aged adults: a cross sectional study

    ✓ Peer-reviewed Brain scans and imaging BMC Neurology

    Key finding: Age and BMI were each associated with decreased brain volume. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2005-12-01

    Stimulation of the subthalamic nucleus in Parkinson's disease: a 5 year follow up

    ✓ Peer-reviewed Clinical safety Journal of neurology, neurosurgery, and psychiatry

    Key finding: Despite moderate motor and cognitive decline, probably due to disease progression, the marked improvement in motor function observed postoperatively was sustained 5 years after neurosurgery. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2005-12-01

    Cognitive decline and literacy among ethnically diverse elders

    ✓ Peer-reviewed Disparities Journal of geriatric psychiatry and neurology

    Key finding: We found that literacy level was a better predictor of decline in memory, executive function, and language skills than was years of education. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2005-12-01

    BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Significantly, deletion of BACE1 in APPswe;PS1DeltaE9 mice prevents both Abeta deposition and age-associated cognitive abnormalities that occur in this model of Abeta amyloidosis. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2005-12-01

    Somatic comorbidity of epilepsy in the general population in Canada

    ✓ Peer-reviewed Disease mechanisms Epilepsia

    Key finding: Multivariate analyses assessed the strength of association of comorbid conditions with epilepsy as compared with the general population. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2005-12-01

    The importance of sequence diversity in the aggregation and evolution of proteins

    ✓ Peer-reviewed Prevention trials Nature

    Key finding: Incorrect folding of proteins, leading to aggregation and amyloid formation, is associated with a group of highly debilitating medical conditions including Alzheimer's disease and late-onset diabetes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2005-12-01

    Clinical aspects of inflammation in Alzheimer's disease

    ✓ Peer-reviewed Treatments International review of psychiatry (Abingdon, England)

    Key finding: There is epidemiological evidence that circulating serum IL-6 is associated with poorer cognition.

    Full summary, score breakdown and related studies → Original source

  8. 2005-12-01

    Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: an fMRI study

    ✓ Peer-reviewed Brain scans and imaging Human brain mapping

    Key finding: The default mode network response in the anterior frontal cortex significantly distinguished MCI from both HC (in the medial frontal) and AD (in the anterior cingulate cortex). +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2005-12-01

    Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Glucose utilization and energy metabolism are regulated by insulin and insulin-like growth factor I (IGF-I), and correspondingly, studies have shown that cognitive impairment may be improved by glucose or insulin administration. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2005-12-01

    Donepezil in the prevention and treatment of post-surgical delirium

    ✓ Peer-reviewed Clinical safety The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: This pilot study was unable to demonstrate a benefit for donepezil in preventing or treating delirium in a relatively young and cognitively-intact group of elderly patients undergoing elective orthopedic surgery. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2005-12-01

    Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo

    ✓ Peer-reviewed Disease mechanisms Neuron

    Full summary, score breakdown and related studies → Original source

  12. 2005-12-01

    Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: a comparative analysis.

    ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Of the simplified methods for PIB analysis examined, CAR90 provided DVR measures that were most comparable to ART90; CER90 was the most reproducible and SUVR90 produced the largest effect size.

    Full summary, score breakdown and related studies → Original source

  13. 2005-12-01

    Novel presenilin 1 mutation (S170F) causing Alzheimer disease with Lewy bodies in the third decade of life

    ✓ Peer-reviewed Risk genes beyond APOE Archives of neurology

    Key finding: Cases of early-onset Alzheimer disease (AD) with an autosomal dominant inheritance pattern (familial AD [FAD]) are rare but have greatly advanced our understanding of the molecular pathogenesis of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2005-12-01

    Hippocampal myo-inositol and cognitive ability in adults with Down syndrome: an in vivo proton magnetic resonance spectroscopy study

    ✓ Peer-reviewed Down syndrome and Alzheimer's Archives of general psychiatry

    Key finding: Adults with DS have a significantly increased brain concentration of myo-inositol, and this is associated with reduced cognitive ability. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2005-12-01

    Sentence processing in frontotemporal dementia

    ✓ Peer-reviewed Digital health tools Cortex; a journal devoted to the study of the nervous system and behavior

    Key finding: The results were correlated with measures of executive resources. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2005-12-01

    Frontotemporal and dopaminergic control of idea generation and creative drive

    ✓ Peer-reviewed Digital health tools The Journal of comparative neurology

    Key finding: These phenomena are clearest in verbal creativity, and roughly parallel the pressured communication of temporal lobe epilepsy, mania, and Wernicke's aphasia-compared to the sparse speech and cognitive inflexibility of depression, Broca's aphasia, and other frontal lobe lesions.

    Full summary, score breakdown and related studies → Original source

  17. 2005-12-01

    Risk of death in elderly users of conventional vs. atypical antipsychotic medications

    ✓ Peer-reviewed How common it is The New England journal of medicine

    Key finding: However, the advisory did not apply to conventional antipsychotic medications; the risk of death with these older agents is not known.

    Full summary, score breakdown and related studies → Original source

  18. 2005-12-01

    Global prevalence of dementia: a Delphi consensus study

    ✓ Peer-reviewed How common it is Lancet (London, England)

    Key finding: Evidence from well-planned, representative epidemiological surveys is scarce in many regions. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2005-12-01

    African American, Chinese, and Latino family caregivers' impressions of the onset and diagnosis of dementia: cross-cultural similarities and differences

    ✓ Peer-reviewed Disparities The Gerontologist

    Key finding: All participants conveyed striking similarities of thought about normalization of cognitive symptoms until one critical event, usually relocation, precipitated family awareness that an elder's behavior was not the result of "normal aging."

    Full summary, score breakdown and related studies → Original source

  20. 2005-12-01

    Antimuscarinic drugs for overactive bladder and their potential effects on cognitive function in older patients

    ✓ Peer-reviewed Caregiving Journal of the American Geriatrics Society

    Key finding: Several of these drugs have been shown to be efficacious in ameliorating the symptoms of OAB in older patients, but most currently available agents lack selectivity for the M3 receptor subtype, and interaction with other muscarinic receptor subtypes throughout the body may adversely affect a variety of physiological functions and result in unwanted side effects, including cognitive dysfunction.

    Full summary, score breakdown and related studies → Original source

  21. 2005-12-01

    Worksite-based internet multimedia program for family caregivers of persons with dementia

    ✓ Peer-reviewed Caregiving The Gerontologist

    Key finding: Those who viewed Caregiver's Friend: Dealing with Dementia 30 days postexposure demonstrated significant improvements in depression, anxiety, level and frequency of stress, caregiver strain, self-efficacy, and intention to seek help, as well as perceptions of positive aspects of caregiving.

    Full summary, score breakdown and related studies → Original source

  22. 2005-12-01

    Unmet care needs and key outcomes in dementia

    ✓ Peer-reviewed Caregiving Journal of the American Geriatrics Society

    Key finding: Unmet need may be useful in identifying dementia care recipients at risk for nursing home placement and death. +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2005-12-01

    Cholesterol in Alzheimer's disease

    ✓ Peer-reviewed Prevention and risk The Lancet. Neurology

    Key finding: Although no single cause of AD has been identified, recent research has suggested that several pathogenetic factors influence risk and expression. +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2005-12-01

    A randomized, double-blind, placebo-controlled trial of two doses of Ginkgo biloba extract in dementia of the Alzheimer's type

    ✓ Peer-reviewed Treatments Current Alzheimer research

    Key finding: The trial did not show efficacy of GbE, however, the lack of decline of the placebo patients may have compromised the sensitivity of the trial to detect a treatment effect. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2005-12-01

    APOE alleles predict the rate of cognitive decline in Alzheimer disease: a nonlinear model

    ✓ Peer-reviewed Genetics Neurology

    Key finding: APOE genotype strongly predicts the rate of cognitive decline in Alzheimer disease.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →