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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,501–24,525 of 27,380 studies, newest first · page 981 of 1096.

May 2003 5

  1. 2003-05-01

    Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease

    ✓ Peer-reviewed Prevention and risk Archives of internal medicine

    Key finding: During a mean follow-up of 3.9 years, dementia was documented in 193 (6.3%) of the 3051 randomized participants in the actively treated group and 217 (7.1%) of the 3054 randomized participants in the placebo group (relative risk reduction, 12% [95% confidence interval, -8% to 28%]; P =.2). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2003-05-01

    The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial

    ✓ Peer-reviewed Prevention and risk Journal of hypertension

    Key finding: In elderly hypertensive patients, a slightly more effective blood pressure reduction during candesartan-based therapy, compared with control therapy, was associated with a modest, statistically non-significant, reduction in major cardiovascular events and with a marked reduction in non-fatal stroke. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2003-05-01

    Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial

    ✓ Peer-reviewed Treatments JAMA

    Key finding: The mean (SD) time between the date of randomization into WHI and the last Modified Mini-Mental State Examination (3MSE) for all WHIMS participants was 4.05 (1.19) years. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2003-05-01

    Neuroimaging in Alzheimer disease: an evidence-based review

    ✓ Peer-reviewed Genetics Neuroimaging clinics of North America

    Key finding: Neuroimaging is valuable in predicting future development of AD in patients with MCI and in carriers of the ApoE epsilon 4 allele who are at a higher risk of developing AD than are cognitively normal elderly individuals. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2003-05-01

    Plasma total cholesterol level as a risk factor for Alzheimer disease: the Framingham Study

    ✓ Peer-reviewed Genetics Archives of internal medicine

    Key finding: In this large, population-based cohort, baseline and long-term average serum total cholesterol levels were not associated with the risk for incident AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

April 2003 20

  1. 2003-04-22

    Mild cognitive impairment: Can FDG-PET predict who is to rapidly convert to Alzheimer's disease?

    ✓ Peer-reviewed Mild cognitive impairment Neurology

    Patients with mild cognitive impairment (MCI) were assessed, and a metabolic profile associated with conversion to AD at 18-month follow-up was sought.

    Full summary, score breakdown and related studies → Original source

  2. 2003-04-22

    Decreased β-Amyloid1-42and Increased Tau Levels in Cerebrospinal Fluid of Patients With Alzheimer Disease

    ✓ Peer-reviewed Biomarkers JAMA

    Alzheimer disease is associated with a significant decrease in CSF beta-amyloid1-42 levels along with an increase in CSF tau levels.

    Full summary, score breakdown and related studies → Original source

  3. 2003-04-21

    Improved exercise tolerance and quality of life with cardiac rehabilitation of older patients after myocardial infarction: results of a randomized, controlled trial

    ✓ Peer-reviewed Prevention and risk Circulation

    Key finding: Post-MI Hosp-CR and Home-CR are similarly effective in the short term and improve TWC and HRQL in each age group. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2003-04-14

    Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

    ✓ Peer-reviewed Disease mechanisms The Journal of Cell Biology

    Key finding: Alzheimer's amyloid precursor protein 695 (APP) is a plasma membrane protein, which is known to be the source of the toxic amyloid beta (Abeta) peptide associated with the pathogenesis of Alzheimer's disease (AD). +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2003-04-01

    A Broken α-Helix in Folded α-Synuclein

    ✓ Peer-reviewed Brain tissue and pathology Journal of Biological Chemistry

    Key finding: alpha-Synuclein is a small cytosolic protein of presynaptic nerve terminals composed of seven 11-residue repeats and a hydrophilic tail. alpha-Synuclein misfolding and dysfunction may contribute to the pathogenesis of Parkinson's disease and neurodegenerative dementias, but its normal folding and function are unknown. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2003-04 month only

    Cerebrospinal fluid tau protein levels in schizophrenia

    ✓ Peer-reviewed Tau biomarkers European archives of psychiatry and clinical neuroscience

    Key finding: Since a more pronounced cognitive decline has been described in older schizophrenic patients, it has been hypothesized that these patients might be at a higher risk of developing AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2003-04-01

    The metallobiology of Alzheimer's disease

    ✓ Peer-reviewed How common it is Trends in neurosciences

    Key finding: Recently, evidence has been gathered to suggest that Abeta precipitation and toxicity in AD are caused by abnormal interactions with neocortical metal ions, especially Zn, Cu and Fe.

    Full summary, score breakdown and related studies → Original source

  8. 2003-04-01

    MAPKs: new targets for neurodegeneration

    ✓ Peer-reviewed End-of-life care Expert opinion on therapeutic targets

    Key finding: For some diseases such as Parkinson's disease, there are currently only palliative therapies, and for others such as Alzheimer's disease there are no proven therapies on the market that have any significant impact on disease progression. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2003-04-01

    Down's syndrome

    ✓ Peer-reviewed Risk factors Lancet (London, England)

    Key finding: Research in prenatal screening and diagnosis aims to find methods to identify fetuses with Down's syndrome, and reduce or eliminate the need for amniocentesis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2003-04-01

    Protein carbonylation in human diseases

    ✓ Peer-reviewed Risk factors Trends in molecular medicine

    Key finding: Oxidative modifications of enzymes and structural proteins play a significant role in the aetiology and/or progression of several human diseases. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2003-04-01

    GSK-3: tricks of the trade for a multi-tasking kinase

    ✓ Peer-reviewed Risk factors Journal of cell science

    Key finding: Another peculiarity compared with other protein kinases is its preference for primed substrates, that is, substrates previously phosphorylated by another kinase.

    Full summary, score breakdown and related studies → Original source

  12. 2003-04-01

    Cholinesterase inhibitors for the treatment of Alzheimer's disease:: getting on and staying on

    ✓ Peer-reviewed Treatments Current therapeutic research, clinical and experimental

    Key finding: ChE inhibitors provide symptomatic benefit in AD across key symptom domains. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2003-04-01

    Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

    ✓ Peer-reviewed Risk genes beyond APOE Neuron

    Key finding: Recent work indicates that gamma-Secretase is a multiprotein complex consisting of Presenilin, Nicastrin, Aph-1, and Pen-2 and that all four proteins are necessary for full proteolytic activity.

    Full summary, score breakdown and related studies → Original source

  14. 2003-04-01

    Alzheimer's disease: the cholesterol connection

    ✓ Peer-reviewed Genetics Nature neuroscience

    Key finding: Elevated cholesterol levels increase Abeta in cellular and most animals models of AD, and drugs that inhibit cholesterol synthesis lower Abeta in these models. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2003-04-01

    Magnetic resonance imaging of hippocampal and amygdala volume in women with childhood abuse and borderline personality disorder

    ✓ Peer-reviewed Hippocampus size on brain scans Psychiatry research

    Key finding: Borderline personality disorder (BPD) is a common disorder associated with emotional dysregulation and other symptoms that have been hypothesized to be related to dysfunction of limbic brain areas including hippocampus and amygdala. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2003-04-01

    Lower respiratory infections in nursing home residents with dementia: a tale of two countries

    ✓ Peer-reviewed End-of-life care The Gerontologist

    Key finding: Nursing home residents with dementia were more often treated without antibiotics in the Netherlands (23%) than in Missouri (15%). +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2003-04-01

    Palliative Excellence in Alzheimer Care Efforts (PEACE): a program description

    ✓ Peer-reviewed End-of-life care Journal of palliative medicine

    Key finding: These interviews assess care domains important for the optimal care of persons with dementia and their caregivers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2003-04-01

    Practical considerations in dialysis withdrawal: "to have that option is a blessing"

    ✓ Peer-reviewed End-of-life care JAMA

    Key finding: Cessation of life-support treatment is an appropriate option for situations in which the burdens of therapy substantially outweigh the benefits. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2003-04-01

    PET studies in dementia

    ✓ Peer-reviewed Cognitive tests and assessment Annals of nuclear medicine

    Key finding: Many studies have documented a close relation between lCMRGlc and localized cognitive functions, such as language and visuoconstructive abilities. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2003-04-01

    Low serum cholesteryl ester-docosahexaenoic acid levels in Alzheimer's disease: a case-control study

    ✓ Peer-reviewed Cognitive tests and assessment The British journal of nutrition

    Key finding: The present case-control study used an established biomarker of n-3 PUFA intake (serum cholesteryl ester-fatty acid composition) to determine n-3 PUFA status in patients with Alzheimer's disease, who were free-living in the community. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →