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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 27,001–27,025 of 27,380 studies, newest first · page 1081 of 1096.

October 1990 3

  1. 1990-10-01

    Morphologic association between microglia and senile plaque amyloid in Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Neuroscience letters

    Key finding: The cell type responsible for the secretion of this amyloid, however, is unknown. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1990-10-01

    Cognitive functions in adult Down's syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's The International journal of neuroscience

    Key finding: With the aim of examining, from a neuropsychological point of view, the modifications that increasing age produces in this group of patients, cognitive performances of younger DS subjects (mean age: 28 years; s.d.: 4.77) were compared with analogous performances obtained by the older ones (mean age: 39.8 years; s.d.: 5.11). +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1990-10-01

    Alzheimer patients and Down patients: abnormal presynaptic terminals are related to cerebral preamyloid deposits

    ✓ Peer-reviewed Down syndrome and Alzheimer's Neuroscience letters

    Key finding: These findings support the view that the deposition of amyloid fibril precursors in the neuropil is closely related to presynaptic terminals, although whether the former precedes or follows the development of presynaptic terminal changes is still undetermined.

    Full summary, score breakdown and related studies → Original source

September 1990 4

  1. 1990-09-01

    Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder

    ✓ Peer-reviewed Brain tissue and pathology Nature

    Key finding: Two recent genetic linkage studies revealed co-segregation of familial Alzheimer disease with the D21S1/S11 and D21S16 loci on chromosome 21. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1990-09-01

    Survival of outpatients with Alzheimer-type dementia

    ✓ Peer-reviewed Cognitive tests and assessment Annals of internal medicine

    Key finding: One hundred and twenty-six patients diagnosed with Alzheimer-type dementia were selected from among 200 consecutive outpatients evaluated for suspected dementia from 1980 to 1982. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1990-09-01

    The amyloid precursor protein of Alzheimer's disease is released by human platelets

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: These species were similar in size to forms seen in brain preparations and in plasma. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1990-09-01

    Involvement of free radicals in dementia of the Alzheimer type: a hypothesis

    ✓ Peer-reviewed Prevention and risk Neurobiology of aging

    Key finding: There is some evidence for increased free radical formation in Down's syndrome which is associated with development of DAT pathology. +1 more finding

    Full summary, score breakdown and related studies → Original source

August 1990 7

  1. 1990-08-01

    Cytochrome oxidase deficiency in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Neurology

    Key finding: Other electron transport chain catalytic activities were not significantly different than control values.

    Full summary, score breakdown and related studies → Original source

  2. 1990-08-01

    Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease

    ✓ Peer-reviewed Health systems and care delivery The American journal of psychiatry

    Key finding: These results suggest that potentially treatable (noncognitive) behavioral and psychiatric symptoms are risk factors for institutionalization, and that treating these symptoms might delay or prevent institutionalization of some patients.

    Full summary, score breakdown and related studies → Original source

  3. 1990-08-01

    Large amounts of neocortical beta A4 deposits without neuritic plaques nor tangles in a psychometrically assessed, non-demented person

    ✓ Peer-reviewed Drug development Neuroscience letters

    Key finding: These data indicate that severe diffuse beta A4 deposits in the neocortex do not induce dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 1990-08-01

    Evolution of spatial cognition: sex-specific patterns of spatial behavior predict hippocampal size

    ✓ Peer-reviewed Hippocampus size on brain scans Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Our controlled comparison suggests that evolution can produce adaptive sex differences in behavior and its neural substrate.

    Full summary, score breakdown and related studies → Original source

  5. 1990-08-01

    Longitudinal evaluation of dementia of the Alzheimer type: a comparison of 3 standardized mental status examinations

    ✓ Peer-reviewed Cognitive tests and assessment Neurology

    Key finding: The 3 tests were readministered to 55 of the patients (2-year subgroup) approximately 1 year later, and administered a 3rd time to 20 of the patients (3-year subgroup) approximately 2 years after their initial assessment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1990-08-01

    Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Phorbol 12,13-dibutyrate, an agent that stimulates protein kinase C, decreased the levels of mature beta APP and increased the levels of 15- and 19-kDa peptides. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1990-08-01

    Neuronal plasticity and astrocytic reaction in Down syndrome and Alzheimer disease

    ✓ Peer-reviewed Biomarkers Journal of the neurological sciences

    Key finding: The observations (normal GS and elevated levels of the other markers) might suggest that the pathological changes involve a differentiated astrocytic reaction and that the astrocytic reaction is more marked in DS than in AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

July 1990 7

  1. 1990-07 month only

    DGAVP (Org 5667) in early Alzheimer's disease patients: an international double-blind, placebo-controlled, multicenter trial

    ✓ Peer-reviewed Clinical trials Neurology

    Key finding: Neither clinical rating scales nor psychometric tests revealed any improvement over 84 days with once-daily intranasal treatment with 2 different doses of DGAVP. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 1990-07-01

    Psychiatric phenomena in Alzheimer's disease. IV: Disorders of behaviour

    ✓ Peer-reviewed Clinical safety The British journal of psychiatry : the journal of mental science

    Key finding: Out of a sample of 178 patients with AD, aggression was present in 20%, wandering in 19%, binge-eating in 10%, hyperorality in 6%, urinary incontinence in 48%, and sexual disinhibition in 7%. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1990-07-01

    Reactive microglia express class I and class II major histocompatibility complex antigens in Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Brain research

    Key finding: Monoclonal antibodies to class I antigens stained reactive microglia weakly to moderately and vascular endothelial cells strongly in Alzheimer's gray and white matter. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1990-07-01

    Brain atrophy in 18 patients with Down syndrome: a CT study

    ✓ Peer-reviewed Down syndrome and Alzheimer's AJNR. American journal of neuroradiology

    Key finding: We compared CT scans of 18 Down syndrome subjects, 26-70 years old (seven of whom satisfied criteria for dementia), with 175 screened normal volunteer control subjects for evidence of cortical and subcortical atrophy. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1990-07-01

    Comprehension of prosody in Huntington's disease

    ✓ Peer-reviewed Digital health tools Journal of neurology, neurosurgery, and psychiatry

    Key finding: Patients with Huntington's Disease (HD) who were without dementia were compared to unilateral stroke patients and controls as previously reported in 1983, to discover if they had a prosodic defect. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1990-07-01

    Selegiline in the treatment of mild to moderate Alzheimer-type dementia

    ✓ Peer-reviewed Treatments Clinical therapeutics

    Key finding: Its efficacy and tolerability were compared with that of phosphatidylserine in a randomized, single-blind, parallel fashion. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 1990-07-01

    Ammonia induced decrease in glial fibrillary acidic protein in cultured astrocytes

    ✓ Peer-reviewed Biomarkers Journal of neuropathology and experimental neurology

    Key finding: Previous studies of human hepatic encephalopathy (HE) have shown decreased levels of glial fibrillary acidic protein (GFAP) in Alzheimer type II astrocytes. +3 more findings

    Full summary, score breakdown and related studies → Original source

June 1990 4

  1. 1990-06-01

    Amyloid beta protein precursor gene and hereditary cerebral hemorrhage with amyloidosis (Dutch)

    ✓ Peer-reviewed Down syndrome and Alzheimer's Science (New York, N.Y.)

    Key finding: Immunohistochemical and biochemical studies have indicated that the amyloid subunit in HCHWA-D is antigenically related to and homologous in sequence with the amyloid beta protein isolated from brains of patients with Alzheimer's disease and Down syndrome. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 1990-06-01

    Effect of antibiotic treatment on outcome of fevers in institutionalized Alzheimer patients

    ✓ Peer-reviewed End-of-life care JAMA

    Key finding: Patients who received diagnostic workup of all fevers and treatment with antibiotics (Antibiotic Group) were compared with patients who received comfort measures only (Palliative Group). +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1990-06-01

    Cleavage of amyloid beta peptide during constitutive processing of its precursor

    ✓ Peer-reviewed Risk genes beyond APOE Science (New York, N.Y.)

    Key finding: Abundant A beta P deposition in the brains of patients with Alzheimer's disease suggests that altered APP processing may represent a key pathogenic event. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 1990-06-01

    Mutation of the Alzheimer's Disease Amyloid Gene in Hereditary Cerebral Hemorrhage, Dutch Type

    ✓ Peer-reviewed Risk genes beyond APOE Science

    An amyloid protein that precipitates in the cerebral vessel walls of Dutch patients with hereditary cerebral hemorrhage with amyloidosis is similar to the amyloid protein in vessel walls and senile plaques in brains of patients with Alzheimer's disease, Down syndrome, and sporadic cerebral amyloid angiopathy.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →