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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,251–24,275 of 27,380 studies, newest first · page 971 of 1096.

January 2004 25

  1. 2004 year only

    Ocular static and dynamic light scattering: a noninvasive diagnostic tool for eye research and clinical practice

    ✓ Peer-reviewed Brain scans and imaging Journal of biomedical optics

    Key finding: The noninvasive techniques of static and dynamic light scattering are emerging as valuable diagnostic tools for the early detection of ocular and systemic diseases. +3 more findings

  2. 2004 year only

    A dual role for apolipoprotein e in neuroinflammation: anti- and pro-inflammatory activity

    ✓ Peer-reviewed Genetics Journal of molecular neuroscience : MN

    Key finding: Chronically activated glia associated with amyloid plaques might contribute to neuronal dysfunction in Alzheimer's disease (AD) through generation of neuroinflammatory molecules. +2 more findings

  3. 2004-01-01

    Prediction of proprotein convertase cleavage sites

    ✓ Peer-reviewed Digital health tools Protein engineering, design & selection : PEDS

    Key finding: Two different types of neural networks have been constructed: a furin-specific network based on experimental results derived from the literature, and a general PC-specific network trained on data from the Swiss-Prot protein database.

  4. 2004-01-01

    Relation of education and occupation-based socioeconomic status to incident Alzheimer's disease

    ✓ Peer-reviewed Disparities American journal of epidemiology

    Key finding: In this study, the authors evaluated whether the association between low educational level and increased risk of Alzheimer's disease (AD) and dementia may be explained by occupation-based socioeconomic status (SES). +4 more findings

  5. 2004-01-01

    Neurodegenerative diseases and oxidative stress

    ✓ Peer-reviewed Inflammation and the immune system Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    Key finding: Nitric oxide (NO(;)), an RNS, which can be produced by three isoforms of NO-synthase in brain, plays a prominent role. +4 more findings

  6. 2004-01-01

    Mapping cortical change in Alzheimer's disease, brain development, and schizophrenia

    ✓ Peer-reviewed Prevention and risk NeuroImage

    Key finding: This paper describes algorithms that can identify patterns of brain structure and function associated with Alzheimer's disease, schizophrenia, normal aging, and abnormal brain development based on imaging data collected in large human populations.

  7. 2004-01-01

    Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease

    ✓ Peer-reviewed Risk factors Neurobiology of aging

    Key finding: The ensuing homeostatic responses to myelin breakdown further increase intracortical toxicity and results in the relentless progression and non-random anatomical distribution of AD lesions that eventually cause neuronal dysfunction and degeneration.

  8. 2004-01-01

    Cholinesterase inhibitors used in the treatment of Alzheimer's disease: the relationship between pharmacological effects and clinical efficacy

    ✓ Peer-reviewed Treatments Drugs & aging

    Key finding: There is also a significant correlation between acetylcholinesterase inhibition and observed cognitive improvement. +3 more findings

  9. 2004-01-01

    Passage of VIP/PACAP/secretin family across the blood-brain barrier: therapeutic effects

    ✓ Peer-reviewed Drug development Current pharmaceutical design

    Key finding: However, uptake of PACAP 38 into the brain is saturable mechanism. +4 more findings

  10. 2004-01-01

    Imaging beta-amyloid plaques and neurofibrillary tangles in the aging human brain

    ✓ Peer-reviewed Treatments Current pharmaceutical design

    Key finding: In vitro studies indicate that amyloid plaques contain multiple binding sites that can accommodate structurally diverse compounds, providing flexibility for radiopharmaceutical design of amyloid imaging agents. +2 more findings

  11. 2004-01-01

    Validity of the Mindstreams computerized cognitive battery for mild cognitive impairment

    ✓ Peer-reviewed Cognitive tests and assessment Journal of molecular neuroscience : MN

    Key finding: Mindstreams outcome parameters across multiple cognitive domains significantly discriminated between MCI and healthy elders with considerable effect sizes (p < 0.05).

  12. 2004-01-01

    Epidemiology of fecal incontinence

    ✓ Peer-reviewed Vascular contributions Gastroenterology

    Key finding: Specific diseases associated with fecal incontinence include diabetes, multiple sclerosis, Parkinson's disease, stroke, and spinal cord injury. +1 more finding

  13. 2004-01-01

    Failures and successes of NMDA receptor antagonists: molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults

    ✓ Peer-reviewed Vascular contributions NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics

    Key finding: Past clinical use for other indications has demonstrated that memantine is well tolerated, and it has recently been approved in both Europe and the USA for the treatment of dementia of the Alzheimer's type.

  14. 2004-01-01

    Effects of hypoxia on the brain: neuroimaging and neuropsychological findings following carbon monoxide poisoning and obstructive sleep apnea

    ✓ Peer-reviewed Hippocampus size on brain scans Journal of the International Neuropsychological Society : JINS

    Key finding: Neuroimaging revealed evidence of hippocampal atrophy in both groups although a linear relationship between hippocampal volume and memory performance was found only for selected tests and only in the sleep apnea group. +3 more findings

  15. 2004-01-01

    Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible

    ✓ Peer-reviewed Hippocampus size on brain scans The European journal of neuroscience

    Key finding: Based on two independent parameters, bromodeoxyuridine (BrdU) and Ki-67 immunocytochemistry, our results show that both chronic and acute stress decrease new cell proliferation rate. +1 more finding

  16. 2004-01-01

    Delayed effects of chronic variable stress during peripubertal-juvenile period on hippocampal morphology and on cognitive and stress axis functions in rats

    ✓ Peer-reviewed Hippocampus size on brain scans Hippocampus

    Key finding: Moreover, these volume deficits were associated with impairments in the Morris water-maze navigation, sustained down-regulation in the basal hippocampal glucocorticoid receptor gene expression, and deficits in the shutdown of acute stress-induced corticosterone secretion. +1 more finding

  17. 2004-01-01

    Relationship between hippocampal volume and memory ability in healthy individuals across the lifespan: review and meta-analysis

    ✓ Peer-reviewed Hippocampus size on brain scans Neuropsychologia

    Key finding: Numerous studies have examined the relationship between memory performance and hippocampal volumes in participants without neurological or psychiatric disorders, with widely varying results. +4 more findings

  18. 2004-01-01

    Advance care planning: preferences for care at the end of life

    ✓ Peer-reviewed End-of-life care Journal of pain & palliative care pharmacotherapy

    Key finding: Predictors of patient wishes and influence of family and clinicians are discussed.

  19. 2004-01-01

    Using antipsychotic agents in older patients

    ✓ Peer-reviewed Clinical safety The Journal of clinical psychiatry

    Key finding: The expert panel reached consensus on 78% of options rated on the 9-point scale.

  20. 2004-01-01

    Delirium in elderly patients

    ✓ Peer-reviewed Clinical safety The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: It occurs in hyperactive, hypoactive, or mixed forms, in up to 50% of elderly hospital inpatients, many with pre-existing dementia, and appears to be independently associated with significant increases in functional disability, length of hospital stay, rates of admission to long-term care institutions, rates of death, and healthcare costs.

  21. 2004-01-01

    Cognitive rehabilitation in Parkinson's disease

    ✓ Peer-reviewed Prevention trials Archives of gerontology and geriatrics. Supplement

    Key finding: At the end of the scheduled sessions, the patients showed a significant improvement at verbal fluency, logic memory and Raven's matrices tests, as compared to baseline. +2 more findings

  22. 2004-01-01

    Dementia with Lewy bodies

    ✓ Peer-reviewed Brain tissue and pathology The Lancet. Neurology

    Key finding: Severe neuroleptic sensitivity reactions are associated with significantly increased morbidity and mortality.

  23. 2004 no date recorded — placed by publication year

    Tai Chi Adapted: Assisted Living, Long-Term Care, and Nursing Homes

    ✓ Peer-reviewed Health systems and care delivery Home Health Care Management &amp; Practice

    Key finding: This article is written to help bridge classic Chinese health care systems with the current complementary/alternative medical point of view. +4 more findings

  24. 2004-01-01

    The Abbey pain scale: a 1-minute numerical indicator for people with end-stage dementia

    ✓ Peer-reviewed Brain tissue and pathology International journal of palliative nursing

    Key finding: Structured approaches to palliative care are not well developed. +3 more findings

  25. 2004-01-01

    A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease

    ✓ Peer-reviewed Brain tissue and pathology Medical hypotheses

    Key finding: Recent studies also show excess neuronal aneuploidy, programmed cell death (PCD), and mitochondrial dysfunction. +3 more findings

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