Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 24,401–24,425 of 27,380 studies, newest first · page 977 of 1096.
August 2003 17
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2003-08-01
Change in Indices of Distress Among Latino and Anglo Female Caregivers of Elderly Relatives With Dementia: Site-Specific Results From the REACH National Collaborative Study
36/100 ✓ Peer-reviewed Disparities The Gerontologist
Key finding: Overall, participants in the Coping With Caregiving condition reported a significant reduction in depressive symptoms, increased use of adaptive coping strategies, and a trend toward decreased use of negative coping strategies when compared with those in the Enhanced Support Group condition. +3 more findings
Full summary, score breakdown and related studies → Original source
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2003-08-01
The Effect of a Family Therapy and Technology-Based Intervention on Caregiver Depression
47/100 ✓ Peer-reviewed Disparities The Gerontologist
Key finding: Caregivers in the combined family therapy and technology intervention experienced a significant reduction in depressive symptoms at 6 months. +3 more findings
Full summary, score breakdown and related studies → Original source
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2003-08-01
Memory-related EEG power and coherence reductions in mild Alzheimer's disease
36/100 ✓ Peer-reviewed Digital health tools International journal of psychophysiology : official journal of the International Organization of Psychophysiology
Key finding: Reduced coherence between central and temporal cortex is discussed in light of a neurological model of AD that hypothesizes reduced electrocortical efficiency and a breakdown of neural network communication to temporal lobes possibly resulting from temporal lobe atrophy. +2 more findings
Full summary, score breakdown and related studies → Original source
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2003-08-01
4-hydroxynonenal as a bioactive marker of pathophysiological processes
36/100 ✓ Peer-reviewed Genetics Molecular aspects of medicine
Key finding: Because there were some excellent reviews on HNE published in recent years, starting in 1990 and 1991 with supreme reviews done by Hermann Esterbauer, who discovered the aldehyde, and colleagues from the Institute of Biochemistry in Graz, this article pays most of attention to the most recent articles, published in the last 15 months. +4 more findings
Full summary, score breakdown and related studies → Original source
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2003-08-01
Donepezil in vascular dementia: a randomized, placebo-controlled study
62/100 ✓ Peer-reviewed Vascular contributions Neurology
Key finding: Donepezil-treated patients demonstrated significant improvements in cognition and global function compared with placebo-treated patients, and donepezil was well tolerated. +4 more findings
Full summary, score breakdown and related studies → Original source
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2003-08-01
Untreated depression and hippocampal volume loss
36/100 ✓ Peer-reviewed Hippocampus size on brain scans The American journal of psychiatry
Key finding: Antidepressants may have a neuroprotective effect during depression. +1 more finding
Full summary, score breakdown and related studies → Original source
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2003-08-01
Alzheimer disease in the US population: prevalence estimates using the 2000 census
51/100 ✓ Peer-reviewed How common it is Archives of Neurology
The number of persons with AD in the US population will continue to increase unless new discoveries facilitate prevention of the disease.
Full summary, score breakdown and related studies → Original source
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2003-08-01
Double blind study of melatonin effects on the sleep-wake rhythm, cognitive and non-cognitive functions in Alzheimer type dementia
43/100 ✓ Peer-reviewed Cognitive tests and assessment Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
Key finding: We conducted a double blind study to examine the effects of melatonin on the sleep-wake rhythm, cognitive and non-cognitive functions in Alzheimer type of dementia. +3 more findings
Full summary, score breakdown and related studies → Original source
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2003-08-01
DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features
52/100 ✓ Peer-reviewed TREM2 and immune genetics The Journal of experimental medicine
Key finding: PLOSL is characterized by cystic bone lesions, osteoporotic features, and loss of white matter in the brain leading to spontaneous bone fractures and profound presenile dementia. +3 more findings
Full summary, score breakdown and related studies → Original source
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2003-08-01
Mild cognitive impairment: directions for future research
48/100 ✓ Peer-reviewed Mild cognitive impairment Neurology
Key finding: Mild cognitive impairment (MCI), an intermediate state between normal aging and dementia, is characterized by acquired cognitive deficits, without significant decline in functional activities of daily living. +1 more finding
Full summary, score breakdown and related studies → Original source
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2003-08-01
Françoise, a fifteen-year follow up
28/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Down's syndrome, research and practice : the journal of the Sarah Duffen Centre
Key finding: Productively, her on-line word finding is becoming problematic, mean length of utterance has halved compared with 15 years ago, and production of compound sentences is reduced.
Full summary, score breakdown and related studies → Original source
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2003-08-01
Acute procoagulant stress response as a dynamic measure of allostatic load in Alzheimer caregivers
41/100 ✓ Peer-reviewed Digital health tools Annals of behavioral medicine : a publication of the Society of Behavioral Medicine
Key finding: Speech stress significantly increased heart rate (p =.017), systolic blood pressure (p =.002), and diastolic blood pressure (p <.001). +1 more finding
Full summary, score breakdown and related studies → Original source
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2003-08-01
Exploring sex differences in the relationship between depressive symptoms and dementia incidence: prospective results from the PAQUID Study
47/100 ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society
Key finding: Ninety-seven men (incidence rate: 14.4/1,000) and 183 women (Incidence rate: 19.0/1,000) developed dementia during 8 years of follow-up. +2 more findings
Full summary, score breakdown and related studies → Original source
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2003-08-01
Changes in premorbid brain volume predict Alzheimer's disease pathology
56/100 ✓ Peer-reviewed Brain scans and imaging Neurology
Key finding: MRI volumes measured over time are valid biomarkers of pathologic progression of AD across a range of antemortem clinical states. +2 more findings
Full summary, score breakdown and related studies → Original source
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2003-08-01
Survival in frontotemporal dementia
57/100 ✓ Peer-reviewed Getting a diagnosis Neurology
Key finding: FTD is a malignant disorder with limited life expectancy. +4 more findings
Full summary, score breakdown and related studies → Original source
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2003-08-01
A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease
46/100 ✓ Peer-reviewed Getting a diagnosis Proteomics
Key finding: Using this approach, we detected statistically significant quantitative differences (p < 0.05) regarding four overexpressed and one underexpressed polypeptides in the CSF of AD patients as compared to healthy controls.
Full summary, score breakdown and related studies → Original source
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2003-08-01
Cognitive reserve and lifestyle
49/100 ✓ Peer-reviewed Prevention and risk Journal of clinical and experimental neuropsychology
Key finding: The concept of cognitive reserve (CR) suggests that innate intelligence or aspects of life experience like educational or occupational attainments may supply reserve, in the form of a set of skills or repertoires that allows some people to cope with progressing Alzheimer's disease (AD) pathology better than others. +2 more findings
Full summary, score breakdown and related studies → Original source
July 2003 8
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2003-07-29
The intracellular domain of the low density lipoprotein receptor-related protein modulates transactivation mediated by amyloid precursor protein and Fe65
44/100 ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry
Key finding: It is implicated in diverse biological processes both as an endocytic receptor and as a signaling molecule. +3 more findings
Full summary, score breakdown and related studies → Original source
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2003-07-22
Endothelial-pericyte interactions in angiogenesis
36/100 ✓ Peer-reviewed Vascular contributions Cell and tissue research
Key finding: Recent interest in pericytes also stems from their potential involvement in diseases such as diabetic microangiopathy, tissue fibrosis, cancer, atherosclerosis and Alzheimer's disease. +4 more findings
Full summary, score breakdown and related studies → Original source
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2003-07-22
Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based study
47/100 ✓ Peer-reviewed Disease mechanisms Brain : a journal of neurology
Key finding: We conclude that the prevalence of FTD in The Netherlands is higher than previously reported, confirming that FTD is more common than was previously thought.
Full summary, score breakdown and related studies → Original source
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2003-07-22
Homogeneity and heterogeneity in mild cognitive impairment and Alzheimer's disease: a cross-sectional and longitudinal study of 55 cases
55/100 ✓ Peer-reviewed Mild cognitive impairment Brain : a journal of neurology
Key finding: This suggests that there is a fairly high degree of homogeneity within this group of patients, and that most of their longitudinal progression can be predicted by dementia severity alone.
Full summary, score breakdown and related studies → Original source
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2003-07-19
The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy
40/100 ✓ Peer-reviewed Disease mechanisms Acta neuropathologica
Key finding: Analysis of the tau gene revealed an L266V mutation in exon 9. +4 more findings
Full summary, score breakdown and related studies → Original source
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2003-07-18
Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy
36/100 ✓ Peer-reviewed Disease mechanisms Proceedings of the National Academy of Sciences of the United States of America
Key finding: FTDP-17 mutation lines had a more severe Unc phenotype, accumulated more insoluble tau at a younger age, were more resistant to cholinergic inhibitors, and had more severe axonal degeneration when compared with lines expressing normal tau.
Full summary, score breakdown and related studies → Original source
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2003-07-09
Voxel-based analysis of MRI reveals anterior cingulate gray-matter volume reduction in posttraumatic stress disorder due to terrorism
36/100 ✓ Peer-reviewed Hippocampus size on brain scans Proceedings of the National Academy of Sciences of the United States of America
Key finding: However, these studies have yielded inconsistent results, and brain structures other than the hippocampus have not been well investigated. +2 more findings
Full summary, score breakdown and related studies → Original source
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2003-07-08
Synucleinopathy pathology and REM sleep behavior disorder plus dementia or parkinsonism
43/100 ✓ Peer-reviewed Risk factors Neurology
Key finding: All had clear histories of dream enactment behavior, and 10 had RBD confirmed by polysomnography. +4 more findings
Full summary, score breakdown and related studies → Original source
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