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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,101–23,125 of 27,380 studies, newest first · page 925 of 1096.

June 2006 25

  1. 2006-06-19

    Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neurochemistry

    Key finding: Owing to their extended morphology, with axons in humans exceeding a meter in length, in addition to which they are not renewed but persist for the entire lifespan, it is no surprise that neurons are highly vulnerable to any perturbation of their sophisticated transport machinery. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2006-06-15

    Exercise, cognition, and the aging brain

    ✓ Peer-reviewed Prevention trials Journal of applied physiology (Bethesda, Md. : 1985)

    Key finding: Finally, we conclude with a summary and brief discussion of important future directions of research on fitness cognition and brain.

    Full summary, score breakdown and related studies → Original source

  3. 2006-06-15

    Oxidative stress in Alzheimer's disease brain: new insights from redox proteomics

    ✓ Peer-reviewed Genetics European journal of pharmacology

    Key finding: Thus, in this review, we discuss the application of redox proteomics for the identification of oxidatively modified proteins in Alzheimer's disease brain and also discuss the functions associated with the identified oxidized proteins in relation to Alzheimer's disease pathology.

    Full summary, score breakdown and related studies → Original source

  4. 2006-06-14

    MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: A role for p38 MAPK in the pathology of Alzheimer disease (AD) has previously been suggested. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2006-06-12

    Pathological and physiological functions of presenilins

    ✓ Peer-reviewed Risk genes beyond APOE Molecular neurodegeneration

    Key finding: Since the first prediction of a genetic link between PSEN1 and PSEN2 with Alzheimer's disease, many research groups from both academia and pharmaceutical industry have sought to unravel how pathogenic mutations in PSEN cause presenile dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2006-06-06

    Validity and reliability of the Edmonton Frail Scale

    ✓ Peer-reviewed Prevention and risk Age and Ageing

    Key finding: Most patients came from the community (43% home without help and 42% home with help compared with 14% in assisted living and 1% in a nursing home). +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2006-06-06

    Lithium and dementia: a preliminary study

    ✓ Peer-reviewed Drug development Progress in neuro-psychopharmacology & biological psychiatry

    Key finding: Recent studies have shown that lithium may block the accumulation of amyloid-beta (Abeta) peptides and to inhibit the hyperphosphorylation of tau via the inhibition of GSK-3alpha in the brain of mice. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2006-06-04

    Correlates and outcomes of dementia among dialysis patients: the Dialysis Outcomes and Practice Patterns Study

    ✓ Peer-reviewed Disparities Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    Key finding: Dementia is associated with adverse outcomes among ESRD patients. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2006-06-02

    Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: In this study we report for the first time that promotion of the NAD+-dependent sirtuin, SIRT1-mediated deacetylase activity, may be a mechanism by which CR influences Alzheimer disease (AD)-type amyloid neuropathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2006-06-01

    Cognitive stimulation therapy for people with dementia: cost-effectiveness analysis

    ✓ Peer-reviewed Costs and economics The British journal of psychiatry : the journal of mental science

    Key finding: Cognitive stimulation therapy for people with dementia has effectiveness advantages over, and may be more cost-effective than, treatment as usual.

    Full summary, score breakdown and related studies → Original source

  11. 2006-06-01

    Estimation of premorbid IQ in individuals with Alzheimer's disease using Japanese ideographic script (Kanji) compound words: Japanese version of National Adult Reading Test

    ✓ Peer-reviewed Risk factors Psychiatry and clinical neurosciences

    Key finding: Further, independent t-tests showed that the JART-predicted IQs were not significantly different between the NE and AD groups, whereas the AD group performed worse in the observed IQs.

    Full summary, score breakdown and related studies → Original source

  12. 2006-06-01

    The chemical biology of clinically tolerated NMDA receptor antagonists

    ✓ Peer-reviewed Treatments Journal of neurochemistry

    Key finding: Phase 3 (final) clinical trials have shown that memantine is effective in treating moderate-to-severe Alzheimer's disease while being well tolerated.

    Full summary, score breakdown and related studies → Original source

  13. 2006-06-01

    The thalamus and behavior: effects of anatomically distinct strokes

    ✓ Peer-reviewed Vascular contributions Neurology

    Key finding: However, recent findings suggest that behavioral patterns can be delineated on the basis of the four main arterial thalamic territories. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2006-06-01

    Brain volume in first-episode schizophrenia: systematic review and meta-analysis of magnetic resonance imaging studies

    ✓ Peer-reviewed Hippocampus size on brain scans The British journal of psychiatry : the journal of mental science

    Key finding: Average volumetric changes are close to the limit of detection by MRI methods. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2006-06-01

    The anorexia of aging in humans

    ✓ Peer-reviewed Clinical safety Physiology & behavior

    Key finding: Energy intake is reduced in older individuals, with several lines of evidence suggesting that both physiological impairment of food intake regulation and non-physiological mechanisms are important. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2006-06-01

    Development and evaluation of home-based speed-of-processing training for older adults

    ✓ Peer-reviewed Prevention trials Archives of physical medicine and rehabilitation

    Key finding: People can improve their processing speed at home using readily available technology. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2006-06-01

    Differential expression of synaptic proteins in the frontal and temporal cortex of elderly subjects with mild cognitive impairment

    ✓ Peer-reviewed Disease mechanisms Journal of neuropathology and experimental neurology

    Key finding: Normalized SYP levels were decreased approximately 35% in the superior temporal and inferior parietal cortex in severe AD compared with NCI. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2006-06-01

    Potential role of dietary n-3 fatty acids in the prevention of dementia and macular degeneration

    ✓ Peer-reviewed Long-term cohort studies The American journal of clinical nutrition

    Key finding: Low dietary intakes and plasma concentrations have been reported to be associated with dementia, cognitive decline, and AMD risk. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2006-06-01

    Visual association pathology in preclinical Alzheimer disease

    ✓ Peer-reviewed Long-term cohort studies Journal of neuropathology and experimental neurology

    Key finding: Imaging studies suggest early changes in posterior brain regions, including posterior temporoparietal and occipital cortex, but pathologic studies show initial changes in the medial temporal lobe with progressive neocortical involvement as cognition deteriorates. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2006-06-01

    High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggression

    ✓ Peer-reviewed Risk genes beyond APOE Journal of child neurology

    Key finding: Although no neuropathologic substrate underlying autism has been found, the findings of brain overgrowth via neuroimaging studies and increased levels of brain-derived neurotrophic factor (BDNF) in neuropathologic and blood studies favor an anabolic state. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2006-06-01

    The ADAMs family: coordinators of nervous system development, plasticity and repair

    ✓ Peer-reviewed Risk genes beyond APOE Progress in neurobiology

    Key finding: In contrast to other metalloproteases, ADAMs are particularly important for cleavage-dependent activation of proteins such as Notch, amyloid precursor protein (APP) and transforming growth factor alpha (TGFalpha), and can bind integrins. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2006-06-01

    Deep brain stimulation: postoperative issues

    ✓ Peer-reviewed Digital health tools Movement disorders : official journal of the Movement Disorder Society

    Key finding: A management plan for problems that can arise after DBS such as weight gain, dyskinesia, axial symptoms, speech dysfunction, muscle contractions, paresthesia, eyelid, ocular and visual disturbances, and behavioral and cognitive problems should be developed. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2006-06-01

    Education, cognitive test scores, and black-white differences in dementia risk

    ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society

    Key finding: Black race was associated with greater dementia risk even after adjustment for education and other potential confounders. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2006-06-01

    Preparedness for the death of a loved one and mental health in bereaved caregivers of patients with dementia: findings from the REACH study

    ✓ Peer-reviewed Disparities Journal of palliative medicine

    Key finding: Despite providing high-intensity care, often for years, many bereaved caregivers perceived themselves as unprepared for the death. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2006-06-01

    Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics

    ✓ Peer-reviewed Caregiving Journal of neurochemistry

    Key finding: A number of clinical trials are currently in progress based on these different therapeutic strategies and they should indicate which, if any, of these approaches will be efficacious. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →