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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 25,601–25,625 of 27,380 studies, newest first · page 1025 of 1096.

January 2000 14

  1. 2000-01-01

    Midlife blood pressure and dementia: the Honolulu-Asia aging study

    ✓ Peer-reviewed How common it is Neurobiology of aging

    Key finding: We assessed the risk (odds ratio (95% CI)) for dementia associated with categories of systolic (SBP) and diastolic blood pressure (DBP), stratified by never/ever treatment with anti-hypertensive medications, and adjusting for age, education, apolipoprotein epsilon allele, smoking and alcohol intake. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2000-01-01

    Atypical parkinsonism in Afro-Caribbean and Indian origin immigrants to the UK

    ✓ Peer-reviewed Disparities Movement disorders : official journal of the Movement Disorder Society

    Key finding: While several workers have suggested that there is a low prevalence of Parkinson's disease in populations of African origin, other workers have suggested a higher prevalence of Parkinson's disease in African Americans. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2000-01-01

    Stage-specific prevalence of behavioral symptoms in Alzheimer's disease in a multi-ethnic community sample

    ✓ Peer-reviewed Disparities The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: As in white patients, overall behavioral symptoms were most frequent among patients with moderate and severe dementia.

    Full summary, score breakdown and related studies → Original source

  4. 2000-01-01

    Working with culture: a qualitative analysis of barriers to the recruitment of Chinese-American family caregivers for dementia research

    ✓ Peer-reviewed Disparities Journal of cross-cultural gerontology

    Key finding: While it is often noted that cultural barriers may make the recruitment of minority elders into research more difficult, relatively little empirical exists to support this claim. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2000-01-01

    Visual analogue scales for pain assessment in Alzheimer's disease

    ✓ Peer-reviewed Disparities Gerontology

    Key finding: Visual analogue scales may improve pain assessment in those AD patients who fully comprehend the meaning of the scales. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2000-01-01

    Prevalence and outcomes of vascular cognitive impairment. Vascular Cognitive Impairment Investigators of the Canadian Study of Health and Aging

    ✓ Peer-reviewed Caregiving Neurology

    Key finding: Failure to consider vascular cognitive impairment without dementia underestimates the prevalence of impairment and the risk for adverse outcomes associated with vascular cognitive impairment. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2000-01-01

    Predicting caregiver burden and depression in Alzheimer's disease

    ✓ Peer-reviewed Caregiving The journals of gerontology. Series B, Psychological sciences and social sciences

    Key finding: Our findings add to the preexisting literature because we tested alternative models of caregiver burden using an unusually large sample size of participants and after overcoming methodological limitations of past research. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2000-01-01

    Estrogen for Alzheimer's disease in women: randomized, double-blind, placebo-controlled trial

    ✓ Peer-reviewed Caregiving Neurology

    Key finding: Although conclusions are limited by small sample size and the possibility of a type II error, results suggest that short-term estrogen therapy does not improve symptoms of most women with AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2000-01-01

    Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory

    ✓ Peer-reviewed Caregiving The Journal of neuropsychiatry and clinical neurosciences

    Key finding: The Neuropsychiatric Inventory (NPI) is a validated clinical instrument for evaluating psychopathology in dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2000-01-01

    Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease

    ✓ Peer-reviewed Getting a diagnosis Archives of neurology

    Key finding: Mean plasma Abeta40 levels were higher in the AD group than in controls (P = .005), but there was substantial overlap; Abeta42 levels were similar between the groups. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2000-01-01

    Chronic traumatic brain injury associated with boxing

    ✓ Peer-reviewed Prevention and risk Seminars in neurology

    Key finding: Chronic traumatic brain injury (CTBI) associated with boxing occurs in approximately 20% of professional boxers. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2000-01-01

    Lecithin for dementia and cognitive impairment

    ✓ Peer-reviewed Treatments The Cochrane database of systematic reviews

    Key finding: Alzheimer's disease sufferers have been found to have a lack of the enzyme responsible for converting choline into acetylcholine within the brain. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2000-01-01

    Nicotine for Alzheimer's disease

    ✓ Peer-reviewed Treatments The Cochrane database of systematic reviews

    Key finding: Nicotine is a cholinergic agonist that acts, not only post-synaptically, but also releases pre-synaptic acetylcholine, and in animal models has been shown to reverse spatial memory decline in rats with lesion in the medial septal nucleus and to show recovery on memory in aged monkeys. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2000-01-01

    The number of trait loci in late-onset Alzheimer disease

    ✓ Peer-reviewed Genetics American journal of human genetics

    Key finding: We found evidence that four additional loci make a contribution to the variance in age at onset of late-onset AD that is similar to or greater in magnitude than that made by apoE, with one locus making a contribution several times greater than that of apoE. +1 more finding

    Full summary, score breakdown and related studies → Original source

December 1999 11

  1. 1999-12-21

    Apolipoprotein E is essential for amyloid deposition in the APP V717F transgenic mouse model of Alzheimer's disease

    ✓ Peer-reviewed Genetics Proceedings of the National Academy of Sciences

    Key finding: The amount of Abeta immunoreactivity in the hippocampus was also markedly reduced in an Apoe gene dose-dependent manner (Apoe(+/+) > Apoe(+/-) >> Apoe(-/-)), and no Abeta immunoreactivity was detected in the cerebral cortex of APP(V717F+/-) Apoe(-/-) TG mice at any of the time points examined. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1999-12-15

    Caregiving as a risk factor for mortality: the Caregiver Health Effects Study

    ✓ Peer-reviewed Caregiving JAMA

    Our study suggests that being a caregiver who is experiencing mental or emotional strain is an independent risk factor for mortality among elderly spousal caregivers.

    Full summary, score breakdown and related studies → Original source

  3. 1999-12-15

    Caregiving as a Risk Factor for Mortality: The Caregiver Health Effects Study

    ✓ Peer-reviewed Caregiving JAMA

    Key finding: 103 of 819 participants (12.6%) died over the ~4.5-year follow-up +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1999-12 month only

    Human apolipoprotein E isoform-specific differences in neuronal sprouting in organotypic hippocampal culture

    ✓ Peer-reviewed Genetics Journal of neurochemistry

    Key finding: In the in vitro mouse organotypic hippocampal slice culture system, we previously showed that cultures derived from ApoE-knockout mice are defective in mossy fiber sprouting into the dentate gyrus molecular layer. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 1999-12-01

    Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction

    ✓ Peer-reviewed Disease mechanisms The Journal of biological chemistry

    Key finding: The copper complex of Abeta1-42 has a highly positive formal reduction potential ( approximately +500-550 mV versus Ag/AgCl) characteristic of strongly reducing cuproproteins. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 1999-12-01

    Antioxidants, oxidative stress, and degenerative neurological disorders

    ✓ Peer-reviewed Disease mechanisms Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)

    Key finding: The results so far are encouraging but variable and thus confusing. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1999-12-01

    Identification of a novel aspartic protease (Asp 2) as beta-secretase

    ✓ Peer-reviewed Risk genes beyond APOE Molecular and cellular neurosciences

    Key finding: Here we report that Asp 2, a novel transmembrane aspartic protease, has the key activities expected of beta-secretase. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1999-12-01

    Rate of memory decline in AD is related to education and occupation: cognitive reserve?

    ✓ Peer-reviewed Vascular contributions Neurology

    Key finding: Memory declined more rapidly in AD patients with higher educational and occupational attainment. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 1999-12-01

    MRI volumes of amygdala and hippocampus in non-mentally retarded autistic adolescents and adults

    ✓ Peer-reviewed Hippocampus size on brain scans Neurology

    Key finding: There is a reduction in the volume of amygdala and hippocampus in people with autism, particularly in relation to total brain volume. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 1999-12-01

    Decrease in cortisol reverses human hippocampal atrophy following treatment of Cushing's disease

    ✓ Peer-reviewed Hippocampus size on brain scans Biological psychiatry

    Key finding: Changes in human HFV associated with sustained hypercortisolemia are reversible, at least in part, once cortisol levels decrease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 1999-12-01

    Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits

    ✓ Peer-reviewed Disease mechanisms Journal of neuropathology and experimental neurology

    Key finding: Positron emission tomography revealed marked glucose hypometabolism that was most severe in left frontal, temporal, and parietal cortical regions. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →