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60/100

✓ Peer-reviewed alzhub usefulness score 60 out of 100. How common it is

Topic: Risk, prevention and care in population studies

Objective To examine the prevalence of mild cognitive impairment (MCI) and its diagnostic classification in the Cardiovascular Health Study (CHS) Cognition Study. Design The CHS Cognition Study is an ancillary study of the CHS that was conducted to determine the presence of MCI and dementia in the CHS cohort. Setting Multicenter population study. Patients We examined 3608 participants in the CHS who had undergone detailed neurological, neuropsychological, neuroradiological, and psychiatric testing to identify dementia and MCI. Main outcome measures The prevalence of MCI was determined for the whole cohort, and specific subtypes of MCI were examined in detail only at the Pittsburgh, Pa, center (n = 927). Mild cognitive impairment was classified as either MCI amnestic-type or MCI multiple cognitive deficits-type. Results The overall prevalence of MCI was 19% (465 of 2470 participants); prevalence increased with age from 19% in participants younger than 75 years to 29% in those older than 85 years. The overall prevalence of MCI at the Pittsburgh center was 22% (130 of 599 participants); prevalence of the MCI amnesic-type was 6% and of the MCI multiple cognitive deficits-type was 16%. Conclusions Twenty-two percent of the participants aged 75 years or older had MCI. Mild cognitive impairment is a heterogeneous syndrome, where the MCI amnestic-type is less frequent than the MCI multiple cognitive deficits-type. Most of the participants with MCI had comorbid conditions that may affect their cognitive functions.

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APA 7th

Lopez, O. L., Jagust, W. J., DeKosky, S. T., Becker, J. T., Fitzpatrick, A., Dulberg, C., et al. (2003). Prevalence and classification of mild cognitive impairment in the Cardiovascular Health Study Cognition Study: part 1. Archives of neurology. https://doi.org/10.1001/archneur.60.10.1385

Vancouver

Lopez OL, Jagust WJ, DeKosky ST, Becker JT, Fitzpatrick A, Dulberg C, et al. Prevalence and classification of mild cognitive impairment in the Cardiovascular Health Study Cognition Study: part 1. Archives of neurology. 2003. doi:10.1001/archneur.60.10.1385. PMID: 14568808.

BibTeX

@article{lopez2003-14568808,
  author  = {Lopez, O. L. and Jagust, W. J. and DeKosky, S. T. and Becker, J. T. and Fitzpatrick, A. and Dulberg, C. and Breitner, J. and Lyketsos, C. and others},
  title   = {{Prevalence and classification of mild cognitive impairment in the Cardiovascular Health Study Cognition Study: part 1}},
  journal = {Archives of neurology},
  year    = {2003},
  doi     = {10.1001/archneur.60.10.1385},
  pmid    = {14568808},
  url     = {https://doi.org/10.1001/archneur.60.10.1385}
}

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Key findings

Results The overall prevalence of MCI was 19% (465 of 2470 participants); prevalence increased with age from 19% in participants younger than 75 years to 29% in those older than 85 years.
The overall prevalence of MCI at the Pittsburgh center was 22% (130 of 599 participants); prevalence of the MCI amnesic-type was 6% and of the MCI multiple cognitive deficits-type was 16%.

Why it matters

In this population study, the overall prevalence of mild cognitive impairment was 19% and rose with age, and the multiple-cognitive-deficit type was more common than the amnestic type. It describes how common a memory problem is and does not test any treatment, cure or prevention.

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Study details

Participants927
Evidence strengthModerate

How this study scored 60/100

Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Archives of neurology)
Journal's citation record	3 / 4	Archives of Neurology: journal h-index 353 (OpenAlex, 2026-10-29)
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	3 / 5	Rated “moderate” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	1 / 5	2003 — older than 20 years, still counted
Sample size	2 / 4	927 participants
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	3 / 3	Studied in people (participant count stated)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	6 / 7	Cited 618 times (OpenAlex, 2026-10-10)
Citations per year	4 / 5	24.7 citations a year over 25 year(s) since 2003
Impact for its field and year	4 / 6	Cited 18.8× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	4 / 6	Cited by 64 other studies in this library
Still being cited	2 / 4	Cited 20 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	4 / 4	Last-listed author Lewis H. Kuller: h-index 173 (OpenAlex, whole career)
Institution's track record	3 / 3	University of Washington: institution h-index 3,540 (OpenAlex)
Multi-centre collaboration	2 / 3	OpenAlex lists 6 institution(s) in 1 country
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 14568808)
Free to read	0 / 2	Behind a paywall — scores zero
Total	60 / 100	—

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