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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 22,226–22,250 of 27,380 studies, newest first · page 890 of 1096.

February 2008 6

  1. 2008-02-01

    Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the Cache County Study

    ✓ Peer-reviewed How common it is International journal of geriatric psychiatry

    Key finding: Participants were most likely to develop depression, apathy, or anxiety, and least likely to develop elation or disinhibition.

    Full summary, score breakdown and related studies → Original source

  2. 2008-02-01

    Association of olfactory dysfunction with risk for future Parkinson's disease

    ✓ Peer-reviewed Getting a diagnosis Annals of neurology

    Key finding: Although olfactory dysfunction is commonly associated with Parkinson's disease (PD), it is not known whether such dysfunction can predate the onset of clinical PD in a community-based population. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2008-02-01

    Diagnosis and treatment of dementia: 1. Risk assessment and primary prevention of Alzheimer disease

    ✓ Peer-reviewed Prevention and risk CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    Key finding: Of 3424 articles on potentially modifiable risk factors for dementia, 1719 met our inclusion criteria; 60 were deemed to be of good or fair quality. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2008-02-01

    Memantine treatment in patients with mild to moderate Alzheimer's disease already receiving a cholinesterase inhibitor: a randomized, double-blind, placebo-controlled trial

    ✓ Peer-reviewed Treatments Current Alzheimer research

    Key finding: In this trial, memantine did not show an advantage over placebo based on protocol-specified primary or secondary analyses in patients with mild to moderate AD on stable ChEI regimens. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2008-02-01

    n-3 Fatty acid erythrocyte membrane content, APOE varepsilon4, and cognitive variation: an observational follow-up study in late adulthood

    ✓ Peer-reviewed Genetics The American journal of clinical nutrition

    Key finding: These data are evidence of a gene x environment interaction for cognitive aging. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2008-02-01

    Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease

    ✓ Peer-reviewed Genetics The Journal of clinical investigation

    Key finding: Abca1(-/-) mice have decreased lipid associated with apoE and increased amyloid deposition in several AD mouse models. +2 more findings

    Full summary, score breakdown and related studies → Original source

January 2008 19

  1. 2008-01-30

    Dimerization of the transmembrane domain of amyloid precursor proteins and familial Alzheimer's disease mutants

    ✓ Peer-reviewed Biomarkers BMC neuroscience

    Key finding: The dissociation constants are correlated to both the Abeta42/Abeta40 ratio and the mean age of disease onset in AD patients.

    Full summary, score breakdown and related studies → Original source

  2. 2008-01-30

    The progression of pathology in longitudinally followed patients with Parkinson's disease

    ✓ Peer-reviewed Lewy body dementia Acta neuropathologica

    Key finding: These cases with higher loads of Lewy bodies and shorter survivals suggest that widespread Lewy body pathology either occurs at the onset of clinical disease or rapidly infiltrates the brain. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2008-01-28

    Statins reduce neuronal alpha-synuclein aggregation in in vitro models of Parkinson's disease

    ✓ Peer-reviewed Drug development Journal of neurochemistry

    Key finding: The function of alpha-syn remains unclear, although several lines of evidence suggest that alpha-syn is involved in synaptic vesicle trafficking probably via lipid binding. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2008-01-26

    Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease

    ✓ Peer-reviewed Treatments Brain research

    Key finding: In the brain a significant increase in rivastigmine uptake was observed in the case of poly(n-butylcyanoacrylate) nanoparticles coated with 1% polysorbate 80 compared to the free drug. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2008-01-26

    Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice

    ✓ Peer-reviewed Hippocampus size on brain scans European journal of pharmacology

    Key finding: The results presented here demonstrate that moderately elevated corticosterone for a prolonged period is sufficient to induce cellular changes in the hippocampus that are prevented by chronic administration of antidepressants.

    Full summary, score breakdown and related studies → Original source

  6. 2008-01-23

    A longitudinal study of drivers with Alzheimer disease

    ✓ Peer-reviewed Clinical safety Neurology

    Key finding: This study confirms previous reports of potentially hazardous driving in persons with early Alzheimer disease, but also indicates that some individuals with very mild dementia can continue to drive safely for extended periods of time. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2008-01-23

    No effect of one-year treatment with indomethacin on Alzheimer's disease progression: a randomized controlled trial

    ✓ Peer-reviewed Cognitive tests and assessment PloS one

    Key finding: The objective of this study was to determine whether treatment with the nonselective nonsteroidal anti-inflammatory drug (NSAID) indomethacin slows cognitive decline in patients with Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2008-01-22

    Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE Trends in molecular medicine

    Key finding: Recent studies of postmortem brains from Alzheimer's disease (AD) patients and transgenic mouse models of AD suggest that oxidative damage, induced by amyloid beta (Abeta), is associated with mitochondria early in AD progression.

    Full summary, score breakdown and related studies → Original source

  9. 2008-01-22

    Cognitive impairment in 873 patients with idiopathic Parkinson's disease. Results from the German Study on Epidemiology of Parkinson's Disease with Dementia (GEPAD)

    ✓ Peer-reviewed Caregiving Journal of neurology

    Key finding: Using established clinical diagnostic standards for dementia the overall rate on routine outpatient neurological care is 28.6%, but using more sensitive neuropsychological measures, rates for cognitive impairment might be up to 2-fold higher. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2008-01-19

    Phosphorylated PP2A (tyrosine 307) is associated with Alzheimer neurofibrillary pathology

    ✓ Peer-reviewed Risk genes beyond APOE Journal of cellular and molecular medicine

    Key finding: In vitro phosphorylation of PP2A catalytic subunit at Y307 efficiently inactivates PP2A. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2008-01-17

    EEG comparisons in early Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease with dementia patients with a 2-year follow-up

    ✓ Peer-reviewed Getting a diagnosis Brain : a journal of neurology

    Key finding: Although it has been suggested that variations in mean EEG frequency are greater in the former, the existence of meaningful differences remains controversial.

    Full summary, score breakdown and related studies → Original source

  12. 2008-01-17

    Automatic classification of MR scans in Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis Brain : a journal of neurology

    Key finding: Data from different centres were successfully combined achieving comparable results from the separate analyses.

    Full summary, score breakdown and related studies → Original source

  13. 2008-01-16

    Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology

    ✓ Peer-reviewed Vascular contributions Neuropathology and applied neurobiology

    Key finding: Elimination of interstitial fluid and solutes plays a role in homeostasis in the brain, but the pathways are unclear. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2008-01-16

    Suppressive effects of flavonoid fisetin on lipopolysaccharide-induced microglial activation and neurotoxicity

    ✓ Peer-reviewed Inflammation and the immune system International immunopharmacology

    Key finding: Our studies showed that fisetin markedly suppressed the production of tumor necrosis factor (TNF)-alpha, NO, and prostaglandin (PG) E2 in lipopolysaccharide (LPS)-stimulated BV-2 microglia cells or primary microglia cultures. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2008-01-16

    Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Abeta is produced by the sequential cleavage of the amyloid precursor protein (APP) by beta- and gamma-secretases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2008-01-16

    Three-dimensional surface mapping of hippocampal atrophy progression from MCI to AD and over normal aging as assessed using voxel-based morphometry

    ✓ Peer-reviewed Mild cognitive impairment Neuropsychologia

    Key finding: In this longitudinal study on patients with mild cognitive impairment (MCI), we used such an approach to map the profile of hippocampal atrophy and its progression over an 18-month follow-up period in rapid converters to AD and "non-converters" compared to age-matched controls. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2008-01-15

    Donepezil improves obstructive sleep apnea in Alzheimer disease: a double-blind, placebo-controlled study

    ✓ Peer-reviewed Treatments Chest

    Key finding: Treatment also increased REM sleep duration and reduced ADAS-cog scores.

    Full summary, score breakdown and related studies → Original source

  18. 2008-01-11

    Depressive symptom trajectories and associated risks among bereaved Alzheimer disease caregivers

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Early intervention to reduce caregiving behavioral burden and enhance family support and promote healthier behaviors of bereaved AD caregivers may decrease the risk of syndromal or syndromal-becoming-threshold level depression after loss. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2008-01-10

    Survival times in people with dementia: analysis from population based cohort study with 14 year follow-up

    ✓ Peer-reviewed Disparities BMJ (Clinical research ed.)

    Key finding: These analyses give a population based estimated median survival for incident dementia of 4.5 years. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →