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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,451–23,475 of 27,380 studies, newest first · page 939 of 1096.

October 2005 25

  1. 2005-10-24

    Links between cognitive impairment in insulin resistance: an explanatory model

    ✓ Peer-reviewed Hippocampus size on brain scans Neurobiology of aging

    Key finding: The mechanism(s) for the cognitive and brain problems associated with impairments in peripheral glucose regulation remain unknown.

    Full summary, score breakdown and related studies → Original source

  2. 2005-10-24

    Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs

    ✓ Peer-reviewed Disease mechanisms The Journal of biological chemistry

    Key finding: (e) Fragmentation of tau(RD) in cells is initially due to a thrombin-like protease activity. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2005-10-21

    Serine hydrolase targets of organophosphorus toxicants

    ✓ Peer-reviewed Risk factors Chemico-biological interactions

    Key finding: Pesticides most commonly shown to inhibit these targets in experimental vertebrates are chlorpyrifos and tribufos. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2005-10-21

    Measurement of thirteen biological markers in CSF of patients with Alzheimer's disease and other dementias

    ✓ Peer-reviewed Biomarkers Dementia and geriatric cognitive disorders

    Key finding: The ratio P-tau181/Abeta42 could significantly distinguish AD patients from all other diagnostic subgroups. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2005-10-20

    TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function

    ✓ Peer-reviewed TREM2 and immune genetics Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

    Key finding: These results provide new evidence that TREM2 regulates OC function independent of its effects on multinucleated OC differentiation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2005-10-20

    P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of clinical investigation

    Key finding: In sporadic, late-onset AD, there is little evidence for increased Abeta production, suggesting that decreased elimination from the brain may contribute to elevated levels of Abeta and plaque formation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2005-10-19

    Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: The new criteria take into account both Lewy-related and Alzheimer disease (AD)-type pathology to allocate a probability that these are associated with the clinical DLB syndrome.

    Full summary, score breakdown and related studies → Original source

  8. 2005-10-19

    Lack of LDL receptor aggravates learning deficits and amyloid deposits in Alzheimer transgenic mice

    ✓ Peer-reviewed Genetics Neurobiology of aging

    Key finding: Emerging evidence indicates that cholesterol metabolism affects the pathogenesis of Alzheimer's disease (AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2005-10-18

    3alpha,5alpha-THP: a potential plasma neurosteroid biomarker in Alzheimer's disease and perhaps non-Alzheimer's dementia

    ✓ Peer-reviewed Biomarkers Psychopharmacology

    Key finding: Lowered 3alpha,5alpha-THP levels appear promising as a biomarker in dementia, but further work is needed to establish the sensitivity and specificity of these findings in AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2005-10-18

    Posttraumatic stress disorder: a state-of-the-science review

    ✓ Peer-reviewed Hippocampus size on brain scans Journal of psychiatric research

    Key finding: (3) Impact of trauma in early life: Persistent increases in CRF concentration are associated with early life trauma and PTSD, and may be reversed with paroxetine treatment.

    Full summary, score breakdown and related studies → Original source

  11. 2005-10-13

    Activation of brain regions vulnerable to Alzheimer's disease: the effect of mild cognitive impairment

    ✓ Peer-reviewed Brain scans and imaging Neurobiology of aging

    Key finding: Our results suggest that a change in function in the PC may account, in part, for memory recollection failure in AD.

    Full summary, score breakdown and related studies → Original source

  12. 2005-10-11

    Obesity, diabetes and cognitive deficit: The Framingham Heart Study

    ✓ Peer-reviewed Risk factors Neurobiology of aging

    Key finding: The gender-specific results for obesity, but not for diabetes, suggests that the underlying mechanisms linking them to cognition may be different. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2005-10-10

    Fish consumption and cognitive decline with age in a large community study

    ✓ Peer-reviewed Prevention trials Archives of neurology

    Key finding: Fish consumption may be associated with slower cognitive decline with age. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2005-10-06

    Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    Key finding: Abeta progressively accumulates in mitochondria and is associated with diminished enzymatic activity of respiratory chain complexes (III and IV) and a reduction in the rate of oxygen consumption.

    Full summary, score breakdown and related studies → Original source

  15. 2005-10-06

    Brain reserve and dementia: a systematic review

    ✓ Peer-reviewed Prevention and risk Psychological medicine

    Key finding: This study demonstrates robust evidence that complex patterns of mental activity in the early, mid- and late-life stages is associated with a significant reduction in dementia incidence. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2005-10-05

    Central and Systemic Endotoxin Challenges Exacerbate the Local Inflammatory Response and Increase Neuronal Death during Chronic Neurodegeneration

    ✓ Peer-reviewed Inflammation and the immune system Journal of Neuroscience

    Key finding: We show that, using the ME7 model of prion disease, intracerebral challenge with LPS results in dramatic interleukin-1beta (IL-1beta) expression, neutrophil infiltration, and inducible nitric oxide synthase expression in the brain parenchyma of prion-diseased mice compared with the same challenge in normal mice.

    Full summary, score breakdown and related studies → Original source

  17. 2005-10-05

    The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease

    ✓ Peer-reviewed Genetics The Journal of biological chemistry

    Key finding: Here we report that the deficiency of ABCA1 does not affect soluble or guanidine-extractable Abeta levels in Tg-SwDI/B or amyloid precursor protein/presenilin 1 (APP/PS1) mice, but rather is associated with a dramatic reduction in soluble apoE levels in brain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2005-10-05

    Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease

    ✓ Peer-reviewed Genetics The Journal of biological chemistry

    Key finding: In contrast to this prediction, 12-month-old PDAPP Abca -/- mice had significantly higher levels of hippocampal Abeta, and cerebral amyloid angiopathy was significantly more common compared with PDAPP Abca1+/+ mice. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2005-10-05

    Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice

    ✓ Peer-reviewed Genetics The Journal of biological chemistry

    Key finding: Recently, it has been reported that the lack of ABCA1 causes a significant reduction of apoE protein level in the brain of ABCA1 knock-out (ABCA1-/-) mice. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2005-10-03

    Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of cell biology

    Key finding: Our results, therefore, link beta-amyloidogenic and cell survival pathways through macroautophagy, which is activated and is abnormal in AD.

    Full summary, score breakdown and related studies → Original source

  21. 2005-10 month only

    Characteristics associated with mobility limitation in long-term care residents with dementia

    ✓ Peer-reviewed Health systems and care delivery The Gerontologist

    Key finding: This article describes the prevalence, assessment, and treatment of, as well as characteristics associated with, mobility limitation in 343 residents with dementia in 45 assisted living facilities and nursing homes. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2005-10 month only

    Dementia care and quality of life in assisted living and nursing homes

    ✓ Peer-reviewed Health systems and care delivery The Gerontologist

    Key finding: Change in quality of life was better in facilities that used a specialized worker approach, trained more staff in more domains central to dementia care, and encouraged activity participation. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2005-10-01

    Prevalence and severity of gait disorders in Alzheimer's and non-Alzheimer's dementias

    ✓ Peer-reviewed Digital health tools Journal of the American Geriatrics Society

    Key finding: The findings support the idea that gait and balance assessment may augment the diagnostic evaluation of dementia.

    Full summary, score breakdown and related studies → Original source

  24. 2005-10-01

    Diagnosis, treatment, and analysis of long-term outcomes in idiopathic normal-pressure hydrocephalus

    ✓ Peer-reviewed Digital health tools Neurosurgery

    Key finding: INPH can be diagnosed accurately with CSF pressure monitoring and CSF drainage via a spinal catheter. +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2005-10-01

    Attitudes, stress, and satisfaction of staff who care for residents with dementia

    ✓ Peer-reviewed Health systems and care delivery The Gerontologist

    Key finding: Stress was more often reported by care providers who had been working for 1 to 2 years (compared with longer); in addition, those who had been working for 1 to 2 years were more likely to espouse hopeful or person-centered attitudes than those who had been working for a longer period of time. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →