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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,151–23,175 of 27,380 studies, newest first · page 927 of 1096.

May 2006 19

  1. 2006-05-01

    Neuropathologic features of amnestic mild cognitive impairment

    ✓ Peer-reviewed Brain tissue and pathology Archives of neurology

    Key finding: The neuropathologic substrate of amnestic mild cognitive impairment (aMCI) is not known. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2006-05-01

    The common inhalation anesthetic isoflurane induces apoptosis and increases amyloid beta protein levels

    ✓ Peer-reviewed Risk genes beyond APOE Anesthesiology

    Key finding: The common inhalation anesthetic isoflurane has previously been reported to enhance the aggregation and cytotoxicity of the Alzheimer disease-associated amyloid beta protein (Abeta), the principal peptide component of cerebral beta-amyloid deposits. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2006-05-01

    Rapid-eye-movement sleep behaviour disorder and neurodegenerative diseases

    ✓ Peer-reviewed Risk factors The Lancet. Neurology

    Key finding: The disorder is strongly associated with neurodegenerative diseases, such as multiple-system atrophy, Parkinson's disease, dementia with Lewy bodies, and progressive supranuclear palsy. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2006-05-01

    Evolution of Parkinson's disease during 4 years of bilateral deep brain stimulation of the subthalamic nucleus

    ✓ Peer-reviewed Digital health tools Movement disorders : official journal of the Movement Disorder Society

    Key finding: Patients with advanced Parkinson's disease (PD) and motor complications can obtain significant symptom improvement by deep brain stimulation (DBS) of the subthalamic nucleus (STN). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2006-05-01

    Motor subtype and cognitive decline in Parkinson's disease, Parkinson's disease with dementia, and dementia with Lewy bodies

    ✓ Peer-reviewed How common it is Journal of neurology, neurosurgery, and psychiatry

    Key finding: Most of PDD and DLB participants were PIGD subtype at baseline assessment. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2006-05-01

    Heart failure and risk of dementia and Alzheimer disease: a population-based cohort study

    ✓ Peer-reviewed How common it is Archives of internal medicine

    Key finding: During the 6534 person-years of follow-up (mean, 5.02 years per person), 440 subjects were diagnosed as having dementia, including 333 with Alzheimer disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2006-05-01

    Conversion of mild cognitive impairment to Alzheimer disease predicted by hippocampal atrophy maps

    ✓ Peer-reviewed How common it is Archives of neurology

    Key finding: Smaller hippocampi and specifically CA1 and subicular involvement are associated with increased risk for conversion from MCI to AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2006-05-01

    Incidence and predictors of seizures in patients with Alzheimer's disease

    ✓ Peer-reviewed How common it is Epilepsia

    Key finding: Seizure incidence is increased in people starting with mild-to-moderate AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2006-05-01

    The effect of social networks on the relation between Alzheimer's disease pathology and level of cognitive function in old people: a longitudinal cohort study

    ✓ Peer-reviewed How common it is The Lancet. Neurology

    Key finding: Cognitive function was inversely related to all measures of disease pathology, indicating lower function at more severe levels of pathology. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2006-05-01

    Limited literacy in older people and disparities in health and healthcare access

    ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society

    Key finding: Cross-sectional study, Health, Aging and Body Composition data (1999/2000). +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2006-05-01

    Determinants of costs of care for patients with Alzheimer's disease

    ✓ Peer-reviewed Caregiving International journal of geriatric psychiatry

    Key finding: Costs of care in patient with AD are high and related to dementia severity as well as presence of behavioural disturbances. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2006-05-01

    Prevalence and severity of microbleeds in a memory clinic setting

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: The authors included 772 patients (53% men, age 66 +/- 11).

    Full summary, score breakdown and related studies → Original source

  13. 2006-05-01

    Neuropathologic outcome of mild cognitive impairment following progression to clinical dementia

    ✓ Peer-reviewed Getting a diagnosis Archives of neurology

    Key finding: The neuropathologic outcome of amnestic MCI following progression to dementia is heterogeneous, and it includes AD at a high frequency. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2006-05-01

    A responder analysis of memantine treatment in patients with Alzheimer disease maintained on donepezil

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: These responder analyses may assist clinicians in evaluating the impact of memantine in a relevant clinical scenario, i.e., in patients with AD previously stabilized on a cholinesterase inhibitor. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2006-05-01

    Effectiveness of collaborative care for older adults with Alzheimer disease in primary care: a randomized controlled trial

    ✓ Peer-reviewed Treatments JAMA

    Key finding: Collaborative care for the treatment of Alzheimer disease resulted in significant improvement in the quality of care and in behavioral and psychological symptoms of dementia among primary care patients and their caregivers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2006-05-01

    Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers

    ✓ Peer-reviewed Genetics Neurology

    Key finding: The degree of coronary artery disease is independently associated with the cardinal neuropathological lesions of Alzheimer disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2006-05-01

    Brain volume changes in CADASIL: a serial MRI study in pure subcortical ischemic vascular disease

    ✓ Peer-reviewed Genetics Neurology

    Key finding: The NBV significantly correlated with all clinical scores (Rankin, NIH Stroke Scale, Barthel, structured interview for the diagnosis of Alzheimer dementia and multi-infarct dementia, Mattis dementia rating scale) at both time points independently of age and sex. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2006-05-01

    The influence of Alzheimer disease family history and apolipoprotein E epsilon4 on mesial temporal lobe activation

    ✓ Peer-reviewed Genetics The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: These findings indicate that FH of AD is an important predictor of hippocampal activation during encoding and that FH may modulate the effect of APOE4 in these middle-aged adults, suggesting that an as yet unspecified factor embodied in first-degree family history of AD is influencing the expression of APOE4 on brain function.

    Full summary, score breakdown and related studies → Original source

  19. 2006-05-01

    Performance-based physical function and future dementia in older people

    ✓ Peer-reviewed Genetics Archives of internal medicine

    Key finding: During follow-up 319 participants developed dementia (221 had AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

April 2006 6

  1. 2006-04-28

    Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: The metal ligand clioquinol (CQ) has shown promising results in animal models and small phase clinical trials; however, the actual mode of action in vivo has not been determined. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2006-04-27

    Transcriptional regulation of APH-1A and increased gamma-secretase cleavage of APP and Notch by HIF-1 and hypoxia

    ✓ Peer-reviewed Risk genes beyond APOE FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    Key finding: Although the four components are known to coordinately regulate each other at the protein level, information regarding their transcription regulation is scarce. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2006-04-25

    Tau protein binds to pericentromeric DNA: a putative role for nuclear tau in nucleolar organization

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of cell science

    Key finding: A nuclear form of tau has been described in neuronal and non-neuronal cells, which displays a nucleolar localization during interphase but is associated with nucleolar-organizing regions in mitotic cells. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2006-04-25

    Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: APP also is cleaved intracytoplasmically at Asp-664 to generate a second cytotoxic peptide, APP-C31, but whether this C-terminal processing of APP plays a role in the pathogenesis of AD is unknown. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2006-04-24

    Caregiver Characteristics Are Associated with Neuropsychiatric Symptoms of Dementia

    ✓ Peer-reviewed Costs and economics Journal of the American Geriatrics Society

    Key finding: Caregivers were on average 64 years old, 72% female, and 49% were the spouse of the patient (32% wives, 17% husbands). +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2006-04-24

    Neprilysin-sensitive synapse-associated amyloid-beta peptide oligomers impair neuronal plasticity and cognitive function

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: However, it is still unclear whether a reduction of the catabolic activity of Abeta in the brain causes neuronal dysfunction in vivo. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →