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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,276–23,300 of 27,380 studies, newest first · page 932 of 1096.

February 2006 16

  1. 2006-02-01

    Alzheimer precursor protein interaction with the Nogo-66 receptor reduces amyloid-beta plaque deposition

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: As part of the disease process, an aberrant axonal sprouting response is known to occur near Abeta deposits. +3 more findings

  2. 2006-02-01

    Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Although this has been known for several decades, the contribution of LC degeneration to AD pathogenesis remains unclear. +3 more findings

  3. 2006-02-01

    Biological rhythm disturbances in mood disorders

    ✓ Peer-reviewed Risk factors International clinical psychopharmacology

    Key finding: The present flourishing of circadian biology has revealed the molecular basis of 24-h rhythmicity driven by 'clock' genes, as well as the importance of zeitgebers (synchronisers).

  4. 2006-02-01

    Steroid-responsive encephalopathy associated with autoimmune thyroiditis

    ✓ Peer-reviewed Risk factors Archives of neurology

    Key finding: The clinical, laboratory, and radiologic findings associated with SREAT are more varied than previously reported. +4 more findings

  5. 2006-02-01

    Role of genes and environments for explaining Alzheimer disease

    ✓ Peer-reviewed How common it is Archives of general psychiatry

    Key finding: In the largest twin study to date, we confirmed that heritability for AD is high and that the same genetic factors are influential for both men and women. +2 more findings

  6. 2006-02-01

    Depressive symptoms and cognitive decline in late life: a prospective epidemiological study

    ✓ Peer-reviewed Disparities Archives of general psychiatry

    Key finding: Depressive symptoms are cross-sectionally associated with cognitive impairment but not subsequent cognitive decline. +4 more findings

  7. 2006-02-01

    Caregivers' reasons for nursing home placement: clues for improving discussions with families prior to the transition

    ✓ Peer-reviewed Caregiving The Gerontologist

    Key finding: Caregivers' reasons for placement included (a) the need for more skilled care (65%); (b) the caregivers' health (49%); (c) the patients' dementia-related behaviors (46%); and (d) the need for more assistance (23%). +3 more findings

  8. 2006-02-01

    Quality of life in dementia: more than just cognition. An analysis of associations with quality of life in dementia

    ✓ Peer-reviewed Caregiving Journal of neurology, neurosurgery, and psychiatry

    Key finding: These data suggest that quality of life in dementia is complex, and that simple proxy substitutions of discrete measures such as cognition or function are likely to miss important factors. +4 more findings

  9. 2006-02-01

    Magnetic resonance imaging of iron deposition in neurological disorders

    ✓ Peer-reviewed Brain scans and imaging Topics in magnetic resonance imaging : TMRI

    Key finding: Iron deposition is associated with a reduction in the T2 relaxation time, leading to hypointensity on spin-echo and gradient-echo T2-weighted images. +1 more finding

  10. 2006-02-01

    Small-world networks and functional connectivity in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Cerebral cortex (New York, N.Y. : 1991)

    Key finding: For a wide range of thresholds, the characteristic path length L was significantly longer in the Alzheimer patients, whereas the cluster coefficient C showed no significant changes.

  11. 2006-02-01

    Mortality after the hospitalization of a spouse

    ✓ Peer-reviewed Getting a diagnosis The New England journal of medicine

    Key finding: Among elderly people hospitalization of a spouse is associated with an increased risk of death, and the effect of the illness of a spouse varies among diagnoses. +3 more findings

  12. 2006-02-01

    Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: longitudinal cohort study

    ✓ Peer-reviewed Getting a diagnosis BMJ (Clinical research ed.)

    Key finding: Elderly people taking anticholinergic drugs had significant deficits in cognitive functioning and were highly likely to be classified as mildly cognitively impaired, although not at increased risk for dementia. +3 more findings

  13. 2006-02-01

    Ageing and the brain

    ✓ Peer-reviewed Prevention and risk Postgraduate medical journal

    Key finding: The brain shrinks with increasing age and there are changes at all levels from molecules to morphology. +4 more findings

  14. 2006-02-01

    Adherence to continuous positive airway pressure treatment in patients with Alzheimer's disease and obstructive sleep apnea

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Patients wore CPAP for 4.8 hours per night. +1 more finding

  15. 2006-02-01

    Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease

    ✓ Peer-reviewed Treatments Neurology

    Key finding: Abeta(1-40) in plasma decreased by 38.2%; in CSF, Abeta(1-40) decreased by 4.42 +/- 9.55% (p = not significant). +1 more finding

  16. 2006-02-01

    Apolipoprotein E and dementia in Parkinson disease: a meta-analysis

    ✓ Peer-reviewed Genetics Archives of neurology

    Key finding: The APOE epsilon4 allele appears to be associated with a higher prevalence of dementia in PD.

January 2006 9

  1. 2006-01-31

    Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease

    ✓ Peer-reviewed Genetics The pharmacogenomics journal

    Key finding: Primary end points at Week 24 were mean change from baseline in AD Assessment Scale-Cognitive (ADAS-Cog) and Clinician's Interview-Based Impression of Change Plus Caregiver Input global scores in the intention-to-treat population (N=511), and results were also stratified by apolipoprotein E (APOE) genotype (n=323). +4 more findings

  2. 2006-01-27

    Pain in elderly people with severe dementia: a systematic review of behavioural pain assessment tools

    ✓ Peer-reviewed Health systems and care delivery BMC geriatrics

    Key finding: Based on the psychometric qualities and criteria regarding sensitivity and clinical utility, we conclude that PACSLAC and DOLOPLUS2 are the most appropriate scales currently available. +2 more findings

  3. 2006-01-25

    The effectiveness of atypical antipsychotics for the treatment of aggression and psychosis in Alzheimer's disease

    ✓ Peer-reviewed Vascular contributions The Cochrane database of systematic reviews

    Key finding: Analysis included patients treated with an atypical antipsychotic, compared with placebo Main results Sixteen placebo controlled trials have been completed with atypical antipsychotics although only nine had sufficient data to contribute to a meta-analysis and only five have been published in full in peer reviewed journals. +4 more findings

  4. 2006-01-25

    BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects

    ✓ Peer-reviewed Hippocampus size on brain scans Biological psychiatry

    Key finding: In spite of a relatively small sample size, the presence of the met-BDNF allele was found associated with a reduced volume of the hippocampal formation in healthy volunteers and may represent a vulnerability factor for the development of disease processes associated with the dysfunction of this brain region. +2 more findings

  5. 2006-01-25

    Donepezil for dementia due to Alzheimer's disease

    ✓ Peer-reviewed Caregiving The Cochrane database of systematic reviews

    Key finding: Selection criteria All unconfounded, double-blind, randomized controlled trials in which treatment with donepezil was compared with placebo for patients with mild, moderate or severe dementia due to Alzheimer's disease. +4 more findings

  6. 2006-01-25

    Galantamine for Alzheimer's disease and mild cognitive impairment

    ✓ Peer-reviewed Treatments The Cochrane database of systematic reviews

    Key finding: Galantamine is a specific, competitive, and reversible acetylcholinesterase inhibitor. +3 more findings

  7. 2006-01-25

    Cholinesterase inhibitors for Alzheimer's disease

    ✓ Peer-reviewed Treatments The Cochrane database of systematic reviews

    Key finding: Since the introduction of the first cholinesterase inhibitor (ChEI) in 1997, most clinicians and probably most patients would consider the cholinergic drugs, donepezil, galantamine and rivastigmine, to be the first line pharmacotherapy for mild to moderate Alzheimer's disease. +3 more findings

  8. 2006-01-24

    Neuropsychological and behavioural correlates of CSF biomarkers in dementia

    ✓ Peer-reviewed Tau biomarkers Neurochemistry international

    Key finding: CSF tau and P-tau181 levels correlated significantly in all groups, whereas CSF Abeta42 correlated with tau and P-tau181 levels in healthy controls only. +2 more findings

  9. 2006-01-13

    Risk factors for incident dementia in England and Wales: The Medical Research Council Cognitive Function and Ageing Study. A population-based nested case-control study

    ✓ Peer-reviewed Disparities Age and ageing

    Key finding: In this large multicentre and long-term population-based study, some well-known risk factors for dementia, of vascular and Alzheimer's type, are confirmed but not others. +2 more findings

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