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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,076–23,100 of 27,380 studies, newest first · page 924 of 1096.

July 2006 12

  1. 2006-07-01

    Mild cognitive impairment: an opportunity to identify patients at high risk for progression to Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Clinical therapeutics

    Key finding: MCI involves more substantial cognitive and memory decline than normal aging and represents a significant risk factor for the development of dementia. +3 more findings

  2. 2006-07-01

    Alzheimer disease with amygdala Lewy bodies: a distinct form of alpha-synucleinopathy

    ✓ Peer-reviewed Lewy body dementia Journal of neuropathology and experimental neurology

    Key finding: The burden of alpha-synuclein pathology in brainstem nuclei, amygdala, and neocortex was significant lower in AD/ALB than in AD/LBD. +1 more finding

  3. 2006-07-01

    99mTc-HMPAO brain perfusion single-photon emission computed tomography in children with Down syndrome: relationship to epilepsy, thyroid functions, and congenital heart disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of child neurology

    Key finding: As a result, the problems of these patients, such as thyroid diseases, leukemia, and Alzheimer disease, would be encountered more frequently. +4 more findings

  4. 2006-07-01

    Telemedicine, dementia and Down syndrome: implications for Alzheimer disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: This study supports the need for formal reliability and validity studies of TM preparatory to the consideration of this modality for use in clinical trials for AD.

  5. 2006-07-01

    Elevated cortical zinc in Alzheimer disease

    ✓ Peer-reviewed Caregiving Neurology

    Key finding: Brain zinc accumulation is a prominent feature of advanced Alzheimer disease (AD) and is biochemically linked to brain amyloid beta-peptide accumulation and dementia severity in AD. +2 more findings

  6. 2006-07-01

    Rapid-eye-movement sleep behaviour disorder as an early marker for a neurodegenerative disorder: a descriptive study

    ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology

    Key finding: 20 (45%) patients developed a neurological disorder after a mean of 11.5 years from the reported onset of RBD and a mean follow-up of 5.1 years from the diagnosis of idiopathic RBD at our sleep centre. +2 more findings

  7. 2006-07-01

    Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis Lancet (London, England)

    Key finding: However, as our knowledge increases so does our appreciation for the pathogenic complexity of the disorder. +4 more findings

  8. 2006-07-01

    Finding potent drugs for Alzheimer's disease is more important than proving the drugs are disease modifying

    ✓ Peer-reviewed Treatments Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Several designs that might prove DM have been proposed, including randomized start, randomized withdrawal, and slope analysis. +4 more findings

  9. 2006-07-01

    Prevention of Alzheimer disease

    ✓ Peer-reviewed Treatments Alzheimer disease and associated disorders

    Key finding: Two types of primary prevention trials have been conducted in AD to date: trials in independent cohorts specifically recruited for an AD primary prevention trial and cohorts in other studies randomized to a drug of interest where appropriate cognitive measures can be added. +4 more findings

  10. 2006-07-01

    Age and apolipoprotein E*4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition

    ✓ Peer-reviewed Genetics Archives of neurology

    Key finding: These CSF A beta 42 findings are consistent with acceleration by the APOE*4 allele of pathogenic A beta 42 brain deposition starting in later middle age in persons with normal cognition. +1 more finding

  11. 2006-07-01

    Conversion to dementia from mild cognitive disorder: the Cache County Study

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Individuals with all types of mild cognitive impairment have an elevated risk of dementia over 3 years, more so in those with an APOE epsilon4 allele. +2 more findings

  12. 2006-07-01

    In vitro analysis of mouse neural stem cells genetically modified to stably express human NGF by a novel multigenic viral expression system

    ✓ Peer-reviewed Biomarkers Neurological research

    Key finding: Features of multipotentiality of engineered NSC-derived cell lines versus naive cells (control-NSC) were assessed by immunocytochemical analysis in differentiation conditions. +4 more findings

June 2006 13

  1. 2006-06-30

    Semantic impairment in stroke aphasia versus semantic dementia: a case-series comparison

    ✓ Peer-reviewed Vascular contributions Brain : a journal of neurology

    Key finding: Different neuropsychological populations implicate diverse cortical regions in semantic memory: semantic dementia (SD) is characterized by atrophy of the anterior temporal lobes whilst poor comprehension in stroke aphasia is associated with prefrontal or temporal-parietal infarcts. +2 more findings

  2. 2006-06-30

    Cognitive decline correlates with neuropathological stage in Parkinson's disease

    ✓ Peer-reviewed Cognitive tests and assessment Journal of the neurological sciences

    Key finding: None of the patients had received the clinical diagnosis of dementia with Lewy bodies. +3 more findings

  3. 2006-06-30
  4. 2006-06-28

    Advance care planning and hospital in the nursing home

    ✓ Peer-reviewed End-of-life care Age and ageing

    Key finding: The intervention area consisted of two hospitals and the 21 nursing homes (NHs) around them compared with another, geographically separate, hospital and the 13 homes around it. +4 more findings

  5. 2006-06-28

    Mitoenergetic failure in Alzheimer disease

    ✓ Peer-reviewed Disease mechanisms American journal of physiology. Cell physiology

    Key finding: Decreasing brain metabolism is a significant cause of cognitive abnormalities of Alzheimer disease (AD), but it remains uncertain whether this is the cause of further pathology or whether synaptic loss results in a lower energy demand. +1 more finding

  6. 2006-06-27

    Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease

    ✓ Peer-reviewed Prevention trials Biological psychiatry

    Key finding: We conclude that structural and molecular prerequisites for activity-dependent plasticity are preserved in mutant mice with an AD-like pathology. +1 more finding

  7. 2006-06-27

    The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation

    ✓ Peer-reviewed Drug development The Journal of biological chemistry

    Key finding: We found that over-activation of Cdk5 in young transgenic animals does not induce tau hyperphosphorylation at sites recognized by the antibodies AT8, AT100, PHF-1, and TG3. +4 more findings

  8. 2006-06-27

    The "posture second" strategy: a review of wrong priorities in Parkinson's disease

    ✓ Peer-reviewed Clinical safety Journal of the neurological sciences

    Key finding: The importance of mental dysfunction is supported by the fact that cognitive loading while walking or balancing can lead to marked deteriorations in postural performance, and there is some evidence to suggest that such "dual tasking" is particularly difficult for elderly persons with dementia or depression. +2 more findings

  9. 2006-06-26

    Neuropsychological effects of bilateral STN stimulation in Parkinson disease

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Louis McDonnell Genome Institute; WGS, whole genome sequencing; WES, whole exome sequencing; indel, insertion-deletion variants; VCF, variant control format; MI, Mendelian inconsistency; MC, Mendelian consistency; GWAS, genome-wide association study; VR, referent allele read depth; DP, overall read depth; MS, mapping score; GQ, genotype quality score; Ti/Tv, Transition/Transversion; CS, concordance code

  10. 2006-06-26

    Neuropathology of older persons without cognitive impairment from two community-based studies

    ✓ Peer-reviewed Brain tissue and pathology Neurology

    Key finding: Two (1.5%) persons met NIA-Reagan criteria for high likelihood AD, and 48 (35.8%) met criteria for intermediate likelihood; 29 (21.6%) had cerebral infarctions, and 18 (13.4%) had Lewy bodies. +4 more findings

  11. 2006-06-25

    Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo

    ✓ Peer-reviewed Risk genes beyond APOE Nature medicine

    Key finding: In Alzheimer disease, accumulation of amyloid-beta (Abeta) in the brain and disease-causing mutations in amyloid precursor protein or in enzymes that produce Abeta indicate dysregulation of production or clearance of Abeta. +3 more findings

  12. 2006-06-23
  13. 2006-06-19

    Hippocampal disconnection contributes to memory dysfunction in individuals at risk for Alzheimer's disease

    ✓ Peer-reviewed Hippocampus size on brain scans Proceedings of the National Academy of Sciences of the United States of America

    Key finding: The present study uses quantitative, high-resolution structural MRI techniques to investigate, in vivo, the anatomical substrate of memory dysfunction associated with MCI. +4 more findings

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