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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 20,501–20,525 of 27,380 studies, newest first · page 821 of 1096.

October 2010 25

  1. 2010-10-22

    Validity and sensitivity to change of the falls efficacy scales international to assess fear of falling in older adults with and without cognitive impairment

    ✓ Peer-reviewed Clinical safety Gerontology

    Key finding: The Short FES-I is a valid measure to assess fear of falling in frail older adults with and without cognitive impairment, yet it may show floor effects in higher functioning older people.

    Full summary, score breakdown and related studies → Original source

  2. 2010-10-22

    Amyloid-beta protein oligomer at low nanomolar concentrations activates microglia and induces microglial neurotoxicity

    ✓ Peer-reviewed Inflammation and the immune system The Journal of biological chemistry

    Key finding: Microglia are activated by aggregated forms of amyloid-β protein (Aβ), usually demonstrated in vitro by stimulating microglia with micromolar concentrations of fibrillar Aβ, a major component of amyloid plaques in AD brains. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2010-10-22

    Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review

    ✓ Peer-reviewed Getting a diagnosis Journal of neurology, neurosurgery, and psychiatry

    Key finding: Imaging studies have detailed the patterns of atrophy associated with different clinical and pathological subtypes.

    Full summary, score breakdown and related studies → Original source

  4. 2010-10-20

    Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease

    ✓ Peer-reviewed Brain tissue and pathology Neurology

    Key finding: The levels of α-synuclein oligomers and oligomers/total-α-synuclein ratio in CSF were higher in the PD group (n = 32; p < 0.0001, Mann-Whitney U test) compared to the control group (n = 28). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2010-10-19

    Atrophy in the parahippocampal gyrus as an early biomarker of Alzheimer's disease

    ✓ Peer-reviewed Hippocampus size on brain scans Brain structure & function

    Key finding: Based on the previous findings, we hypothesized that there would be significant volume differences between cases of healthy aging, amnestic mild cognitive impairment (aMCI), and mild AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2010-10-18

    Oophorectomy, menopause, estrogen treatment, and cognitive aging: clinical evidence for a window of opportunity

    ✓ Peer-reviewed Brain tissue and pathology Brain research

    Key finding: We explored the window of opportunity hypothesis in relation to cognitive aging and dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2010-10-15

    Brain endothelial cells produce amyloid {beta} from amyloid precursor protein 770 and preferentially secrete the O-glycosylated form

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Aβ is generated from amyloid precursor protein (APP) by the actions of β- and γ-secretases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2010-10-15

    What the left and right anterior fusiform gyri tell us about semantic memory

    ✓ Peer-reviewed How common it is Brain : a journal of neurology

    Key finding: Although it is well-known that semantic dementia is associated with temporal lobe degeneration, controversy remains over whether the semantic deficit is due to diffuse temporal lobe damage, damage to only a sub-region of the temporal lobe or even less severe damage elsewhere in the brain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2010-10-14

    Risk factors for bullous pemphigoid in the elderly: a prospective case-control study

    ✓ Peer-reviewed Health systems and care delivery The Journal of investigative dermatology

    Key finding: Factors independently associated with BP by multivariate analysis were major cognitive impairment (odds ratio (OR), 2.19; 95% confidence interval (95% CI), 1.24-3.87), bedridden condition (OR, 2.19; 95% CI, 1.23-3.89), Parkinson's disease (OR, 2.16; 95% CI, 1.09-4.27), unipolar or bipolar disorder (OR, 5.25; 95% CI, 1.21-22.86), and chronic use of spironolactone (OR, 2.30; 95% CI, 1.20-4.46) or phenothiazines with aliphatic side chains (OR, 3.70; 95% CI, 1.21-11.34). +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2010-10-14

    Galantamine-induced amyloid-{beta} clearance mediated via stimulation of microglial nicotinic acetylcholine receptors

    ✓ Peer-reviewed Inflammation and the immune system The Journal of biological chemistry

    Key finding: We found that in human AD brain, microglia accumulated on Aβ deposits and expressed α7 nAChRs including the APL-binding site recognized with FK1 antibody. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2010-10-13

    Aberrant subcellular neuronal calcium regulation in aging and Alzheimer's disease

    ✓ Peer-reviewed Drug development Biochimica et biophysica acta

    Key finding: Altered proteolytic cleavage of the β-amyloid precursor protein (APP) in response to the aging process in combination with genetic and environmental factors results in the production and accumulation of neurotoxic forms of amyloid β-peptide (Aβ). +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2010-10-12

    Anti-inflammatory impact of minocycline in a mouse model of tauopathy

    ✓ Peer-reviewed Disease mechanisms Frontiers in psychiatry

    Key finding: Increasing evidence suggests that neuroinflammatory processes contribute to the progression of AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2010-10-11

    Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: To date, there has been no extensive analysis of alterations in synaptic mitochondria associated with amyloid pathology in an amyloid β (Aβ)-rich milieu. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2010-10-11

    Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue

    ✓ Peer-reviewed Lewy body dementia PloS one

    Key finding: Increasing evidence indicates that TDP-43 regulates mRNA metabolism by interacting with mRNA binding proteins that are known to associate with RNA granules. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2010-10-09

    Activation and effective connectivity changes following explicit-memory training for face-name pairs in patients with mild cognitive impairment: a pilot study

    ✓ Peer-reviewed Brain scans and imaging Neurorehabilitation and neural repair

    Key finding: The authors' findings suggest that the effectiveness of explicit-memory training in patients with MCI is associated with training-specific increases in activation and connectivity in a distributed neural system that includes areas involved in explicit memory. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2010-10-09

    Revising the definition of Alzheimer's disease: a new lexicon

    ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology

    Key finding: The recent advances in use of reliable biomarkers of AD that provide in-vivo evidence of the disease has stimulated the development of new research criteria that reconceptualise the diagnosis around both a specific pattern of cognitive changes and structural/biological evidence of Alzheimer's pathology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2010-10-08

    Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Brain : a journal of neurology

    Key finding: We used a new method of pooling cerebrospinal fluid Aβ42 and Pittsburgh compound B positron emission tomography measures to produce equivalent measures of brain Aβ load from either source and analysed the results using multiple imputation methods. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2010-10-07

    Experimental models of vascular dementia and vascular cognitive impairment: a systematic review

    ✓ Peer-reviewed Brain tissue and pathology Journal of neurochemistry

    Key finding: The main causes of VCI are: cerebral small vessel disease; multi-infarct dementia; strategic infarct (i.e. located in a functionally-critical brain area); haemorrhage/microbleed; angiopathy (including cerebral amyloid angiopathy); severe hypoperfusion (e.g. cardiac arrhythmia); and hereditary vasculopathy (e.g. cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, CADASIL). +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2010-10-05

    The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women

    ✓ Peer-reviewed Risk factors International journal of obesity (2005)

    Key finding: IER is as effective as CER with regard to weight loss, insulin sensitivity and other health biomarkers, and may be offered as an alternative equivalent to CER for weight loss and reducing disease risk.

    Full summary, score breakdown and related studies → Original source

  20. 2010-10-04

    Aggregation of detergent-insoluble tau is involved in neuronal loss but not in synaptic loss

    ✓ Peer-reviewed Disease mechanisms The Journal of biological chemistry

    Key finding: In neurodegenerative diseases, neuronal dysfunction due to neuronal loss and synaptic loss accompanies NFT formation, suggesting that a process associated with NFT formation may be involved in neuronal dysfunction. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2010-10-01

    Flavonoids and Isoflavonoids: From Plant Biology to Agriculture and Neuroscience

    ✓ Peer-reviewed Prevention and risk PLANT PHYSIOLOGY

    Key finding: For example, the early advances in floral genetics were primarily the result of the ease of screening for mutations impacting flavonoid-derived flower colors, and the first demonstration of epigenetic gene silencing in plants was likewise associated with flavonoid biosynthesis (Jorgensen, 1995). +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2010-10-01

    A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: There is an urgent need for novel therapeutic approaches for AD.

    Full summary, score breakdown and related studies → Original source

  23. 2010-10-01

    Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study

    ✓ Peer-reviewed Genetics The Lancet. Neurology

    Key finding: In this analysis, two single nucleotide polymorphisms in a locus on chromosome 9p21.2 were associated with ALS: rs3849942 (p=2·22×10(-6); odds ratio [OR] 1·39, 95% CI 1·21-1·59) and rs2814707 (p=3·32×10(-6); 1·38, 1·20-1·58). +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2010-10-01

    Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study

    ✓ Peer-reviewed Genetics The Lancet. Neurology

    Key finding: Within this region, we defined a 42-SNP haplotype that was associated with significantly increased risk of ALS (p=7·47×10(-33) when people with familial ALS were compared with controls, odds ratio 21·0, 95% CI 11·2-39·1) and which overlapped with an association locus recently reported for frontotemporal dementia.

    Full summary, score breakdown and related studies → Original source

  25. 2010-10-01

    Patient characteristics associated with oral anticoagulation control: results of the Veterans AffaiRs Study to Improve Anticoagulation (VARIA)

    ✓ Peer-reviewed Vascular contributions Journal of thrombosis and haemostasis : JTH

    Key finding: Some patients receiving oral anticoagulation therapy are more challenging to maintain within the therapeutic range than others. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →