Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 21,076–21,100 of 27,380 studies, newest first · page 844 of 1096.
January 2010 25
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2010-01-01
Interethnic Differences in Dementia Epidemiology: Global and Asia-Pacific Perspectives
38/100 ✓ Peer-reviewed Risk factors Dementia and Geriatric Cognitive Disorders
Key finding: More recent work has suggested differences: migrant populations attain rates between their homelands and adopted countries, and higher rates have been found in African Americans and Hispanics compared to Caucasian Whites, and also among native Australians. +1 more finding
Full summary, score breakdown and related studies → Original source
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2010-01-01
Geographic Variation in One-Year Recurrent Ischemic Stroke Rates for Elderly Medicare Beneficiaries in the USA
42/100 ✓ Peer-reviewed Risk factors Neuroepidemiology
Key finding: The overall 1-year recurrent stroke rate was 9.4% among 895,916 ischemic stroke patients (mean age: 78 years; 56.6% women; 86.6% White, 9.7% Black and 1.2% Latino/Hispanic). +4 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
The Oldest Old in the Last Year of Life: Population‐Based Findings from Cambridge City over‐75s Cohort Study Participants Aged 85 and Older at Death
46/100 ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society
Key finding: Functional and cognitive impairments were markedly higher for those who died aged 90 and older- predominantly women-than for those who died aged 85 to 89. +4 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
Assessment of productivity performance in men with HIV Associated Neurocognitive Disorder (HAND)
31/100 ✓ Peer-reviewed Risk factors Work
Key finding: The participant demonstrated 28.6% mastery of the grocery shopping task. +3 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy
46/100 ✓ Peer-reviewed Inflammation and the immune system Journal of Alzheimer's disease : JAD
Key finding: It exacerbates the fundamental pathology by generating a plethora of inflammatory mediators and neurotoxic compounds. +3 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer's disease
45/100 ✓ Peer-reviewed Brain tissue and pathology Current pharmaceutical design
Key finding: The increase of life-expectancy is transforming AD into a major health-care problem. +3 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
Osteopontin is increased in the cerebrospinal fluid of patients with Alzheimer's disease and its levels correlate with cognitive decline
40/100 ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD
Key finding: Osteopontin (OPN) is a molecule involved in macrophage recruitment and activation and implicated in neurodegeneration. +3 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
Age and education effects and norms on a cognitive test battery from a population-based cohort: the Monongahela-Youghiogheny Healthy Aging Team
42/100 ✓ Peer-reviewed Cognitive tests and assessment Aging & mental health
Key finding: Performance on cognitive tests can be affected by age, education, and also selection bias. +3 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
Attempted suicide in the elderly: characteristics of suicide attempters 70 years and older and a general population comparison group
46/100 ✓ Peer-reviewed Cognitive tests and assessment The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Key finding: Social, psychological, and psychiatric characteristics were compared in suicide attempters (70 years and older) and a representative population sample. +3 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
The Mini Mental State Examination: Review of cutoff points adjusted for schooling in a large Southern Brazilian sample
47/100 ✓ Peer-reviewed Cognitive tests and assessment Dementia & neuropsychologia
Key finding: Instruments that evaluate cognitive functions such as the Mini Mental State Examination (MMSE) are necessary for the investigation of dementia. +3 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
Biomarkers as predictors for conversion from mild cognitive impairment to Alzheimer-type dementia: implications for trial design
63/100 ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD
Key finding: In this review we summarized biomarkers in cerebrospinal fluid (CSF) and blood that can predict AD-type dementia in subjects with mild cognitive impairment (MCI). +3 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice
41/100 ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD
Key finding: In contrast, sporadic AD has been proposed to start with an insulin-resistant brain state (IRBS).We investigated the effect of IRBS induced by intracerebroventricularly (icv) administered streptozotocin (STZ) on behavior, glycogen synthase kinase-3 (GSK) alpha/beta content, and the formation of AD-like morphological hallmarks Abeta and tau protein in AbetaPP Tg2576 mice. +3 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
Metabolic syndrome and cognitive impairment: current epidemiology and possible underlying mechanisms
42/100 ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD
Key finding: At present, cumulative evidence suggests that vascular risk factors may be important in the development of mild cognitive impairment (MCI), dementia, and AD. +3 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
Nutraceutical properties of Mediterranean diet and cognitive decline: possible underlying mechanisms
44/100 ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD
Key finding: Recent prospective studies provided evidence that higher adherence to a Mediterranean-type diet could be associated with slower cognitive decline, reduced risk of progression from mild cognitive impairment to Alzheimer's disease (AD), reduced risk of AD, and decreased mortality in AD patients. +1 more finding
Full summary, score breakdown and related studies → Original source
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2010-01-01
Regional selectivity of rab5 and rab7 protein upregulation in mild cognitive impairment and Alzheimer's disease
40/100 ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD
Key finding: Previous microarray and real-time quantitative PCR experiments revealed an upregulation of the early endosomal effector rab5 and the late endosome constituent rab7 in the hippocampus of people with mild cognitive impairment (MCI) and AD. +1 more finding
Full summary, score breakdown and related studies → Original source
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2010-01-01
Neuropathologic alterations in mild cognitive impairment: a review
45/100 ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD
Key finding: These findings are not surprising because most MCI autopsied cases have been in the older (80 to 90 year) range where these findings are common. +1 more finding
Full summary, score breakdown and related studies → Original source
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2010-01-01
Neuropsychiatric predictors of progression from amnestic-mild cognitive impairment to Alzheimer's disease: the role of depression and apathy
49/100 ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD
Key finding: Patients with both amnestic-MCI and an apathy diagnosis had an almost sevenfold risk of AD progression compared to amnestic-MCI patients without apathy (HR=6.9; 2.3-20.6), after adjustment for age, gender, education, baseline global cognitive and functional status, and depression. +2 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
Role of oxidative stress in the progression of Alzheimer's disease
45/100 ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD
Key finding: In this review, we summarize evidence for a role of oxidative stress in the progression of AD by comparing the appearance of the same oxidized brain proteins from subjects with mild cognitive impairment (MCI), early AD (EAD), and late-stage AD, and relating these findings to the reported AD pathology. +1 more finding
Full summary, score breakdown and related studies → Original source
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2010-01-01
Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis
54/100 ✓ Peer-reviewed Lewy body dementia The Journal of neuroscience : the official journal of the Society for Neuroscience
Key finding: Expression of mutant TDP-43 was toxic to neurons, and mutant-specific toxicity was associated with increased cytoplasmic mislocalization of TDP-43. +1 more finding
Full summary, score breakdown and related studies → Original source
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2010-01-01
Diabetes and cognitive systems in older black and white persons
55/100 ✓ Peer-reviewed Disparities Alzheimer disease and associated disorders
Key finding: In summary, diabetes was associated with semantic memory impairment in both black and white persons. +1 more finding
Full summary, score breakdown and related studies → Original source
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2010-01-01
Impact of FDA black box advisory on antipsychotic medication use
42/100 ✓ Peer-reviewed Disparities Archives of internal medicine
Key finding: The FDA advisory was associated with decreases in the use of atypical antipsychotics, especially among elderly patients with dementia. +2 more findings
Full summary, score breakdown and related studies → Original source
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2010-01-01
Enhancing caregiver health: findings from the resources for enhancing Alzheimer's caregiver health II intervention
65/100 ✓ Peer-reviewed Caregiving Journal of the American Geriatrics Society
Key finding: A structured, multicomponent skills training intervention that targeted CG self-care behaviors as one of five target areas, improved self-reported health status, and decreased burden and bother in racially and ethnically diverse CGs of people with dementia.
Full summary, score breakdown and related studies → Original source
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2010-01-01
Dying with dementia: what we know after more than a decade of research
48/100 ✓ Peer-reviewed Caregiving Journal of Alzheimer's disease : JAD
Key finding: With increasing numbers of well-designed, large-scale studies, research in the next decade may result in better evidence-based guidelines and practice.
Full summary, score breakdown and related studies → Original source
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2010-01-01
Dementia incidence continues to increase with age in the oldest old: the 90+ study
63/100 ✓ Peer-reviewed Caregiving Annals of neurology
Key finding: Incidence of all-cause dementia is very high in people aged 90 years and older and continues to increase exponentially with age in both men and women. +1 more finding
Full summary, score breakdown and related studies → Original source
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2010-01-01
Mapping brain morphological and functional conversion patterns in amnestic MCI: a voxel-based MRI and FDG-PET study
45/100 ✓ Peer-reviewed Brain scans and imaging European journal of nuclear medicine and molecular imaging
Key finding: The discordant topography between atrophy and hypometabolism reported in AD is already present at the aMCI stage. +3 more findings
Full summary, score breakdown and related studies → Original source
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