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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 21,326–21,350 of 27,380 studies, newest first · page 854 of 1096.

August 2009 16

  1. 2009-08-04

    The underrecognized epidemic of low mobility during hospitalization of older adults

    ✓ Peer-reviewed How common it is Journal of the American Geriatrics Society

    Key finding: This is the first study to continuously monitor mobility levels early during a hospital stay. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2009-08-01

    Human brain networks in health and disease

    ✓ Peer-reviewed Brain scans and imaging Current opinion in neurology

    Key finding: Recent developments in the statistical physics of complex networks have been translated to neuroimaging data in an effort to enhance our understanding of human brain structural and functional networks. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2009-08-01

    The Role of Apolipoprotein E in Alzheimer's Disease

    ✓ Peer-reviewed Risk genes beyond APOE Neuron

    Key finding: The epsilon4 allele of apolipoprotein E (APOE) is the major genetic risk factor for Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2009-08-01

    Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia

    ✓ Peer-reviewed Inflammation and the immune system Annals of neurology

    Key finding: By combining double immunohistochemistry, laser capture microdissection, and highly sensitive multiplexed polymerase chain reaction to detect HIV DNA in single astrocytes in vivo, we showed that astrocyte infection is extensive in subjects with HIV-associated dementia, occurring in up to 19% of GFAP+ cells. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2009-08-01

    Cerebrospinal fluid amyloid beta(40) is decreased in cerebral amyloid angiopathy

    ✓ Peer-reviewed Tau biomarkers Annals of neurology

    Key finding: In analogy to previous observations in Alzheimer disease, we hypothesized that analysis of amyloid beta(40) and beta(42) proteins in the cerebrospinal fluid might serve as a molecular biomarker. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2009-08-01

    DNA methylation of Alzheimer disease and tauopathy-related genes in postmortem brain

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neuropathology and experimental neurology

    Key finding: To determine the feasibility of DNA methylation studies in the postmortem human brain, we evaluated brain samples with variable postmortem artificially increased delays up to 48 hours. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2009-08-01

    Anti-Alzheimer and antioxidant activities of Coptidis Rhizoma alkaloids

    ✓ Peer-reviewed Risk genes beyond APOE Biological & pharmaceutical bulletin

    Key finding: Thus, the anti-Alzheimer and antioxidant effects of six protoberberine alkaloids (berberine, palmatine, jateorrhizine, epiberberine, coptisine, and groenlandicine) and one aporphine alkaloid (magnoflorine) from Coptidis Rhizoma were evaluated via beta-site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) assays, along with peroxynitrite (ONOO(-)) scavenging and total reactive oxygen species (ROS) inhibitory assays. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2009-08-01

    Early diagnosis of Alzheimer's disease: is MCI too late?

    ✓ Peer-reviewed Mild cognitive impairment Current Alzheimer research

    Key finding: In the interim, the construct of mild cognitive impairment (MCI) has come to represent an intermediate clinical state between the cognitive changes of aging and the very earliest features of Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2009-08-01

    The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset?

    ✓ Peer-reviewed Caregiving Neuropathology and applied neurobiology

    Key finding: These observations: (i) support the hypothesis of transneuronal spread of neurofibrillary changes from the DR to its interconnected cortical brain areas; and (ii) indicate that the supratrochlear subnucleus of the DR is affected by neurofibrillary changes before the transentorhinal cortex during the disease process underlying AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2009-08-01

    Regional rates of neocortical atrophy from normal aging to early Alzheimer disease

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Atrophy is not uniform across regions, nor does it follow a linear trajectory. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2009-08-01

    Baseline MRI predictors of conversion from MCI to probable AD in the ADNI cohort

    ✓ Peer-reviewed Getting a diagnosis Current Alzheimer research

    Key finding: We analyzed baseline 1.5T MRI scans in 693 participants from the ADNI cohort divided into four groups by baseline diagnosis and one year MCI to probable AD conversion status to identify neuroimaging phenotypes associated with MCI and AD and potential predictive markers of imminent conversion. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2009-08-01

    The neuropathology of probable Alzheimer disease and mild cognitive impairment

    ✓ Peer-reviewed Getting a diagnosis Annals of neurology

    Key finding: Of 179 persons (average age, 86.9 years) with probable AD, 87.7% had pathologically confirmed AD, and 45.8% had mixed pathologies, most commonly AD with macroscopic infarcts (n = 54), followed by AD with neocortical LB disease (n = 19) and both (n = 8).

    Full summary, score breakdown and related studies → Original source

  13. 2009-08-01

    Adherence to a Mediterranean diet, cognitive decline, and risk of dementia

    ✓ Peer-reviewed Prevention and risk JAMA

    Key finding: Higher adherence to a Mediterranean diet was associated with slower MMSE cognitive decline but not consistently with other cognitive tests. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2009-08-01

    Physical activity, diet, and risk of Alzheimer disease

    ✓ Peer-reviewed Prevention and risk JAMA

    Key finding: In this study, both higher Mediterranean-type diet adherence and higher physical activity were independently associated with reduced risk for AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2009-08-01

    The Indiana Alzheimer Disease Center's Symposium on Mild Cognitive Impairment. Cognitive training in older adults: lessons from the ACTIVE Study

    ✓ Peer-reviewed Treatments Current Alzheimer research

    Key finding: The results of the ACTIVE study (Advanced Cognitive Training for Independent and Vital Elderly) were presented at the symposium including review of previously published study findings. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2009-08-01

    The efficacy, safety, and tolerability of donepezil for the treatment of young adults with Down syndrome

    ✓ Peer-reviewed Treatments American journal of medical genetics. Part A

    Key finding: During the double-blind phase, SIB scores improved significantly from baseline in both groups, with no significant between-group differences. +1 more finding

    Full summary, score breakdown and related studies → Original source

July 2009 9

  1. 2009-07-29

    Vitamin D and cognitive performance in adults: a systematic review

    ✓ Peer-reviewed Clinical safety European journal of neurology

    Key finding: Chronic low serum 25-hydroxyvitamin D (25OHD) concentrations are common in adults and are associated with numerous non-skeletal diseases. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2009-07-27

    Chronic temporal lobe epilepsy: a neurodevelopmental or progressively dementing disease?

    ✓ Peer-reviewed Brain tissue and pathology Brain : a journal of neurology

    Key finding: We examined cross-sectional comparisons of age-related regressions of verbal learning and memory in 1156 patients with chronic TLE (age range 6-68 years, mean epilepsy onset 14 +/- 11 years) versus 1000 healthy control subjects (age range 6-80 years) and tested the hypothesis that deviations of age regressions (i.e. slowed rise, accelerated decline) will reveal critical phases during which epilepsy interferes with cognitive development. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2009-07-27

    Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

    ✓ Peer-reviewed Lewy body dementia Proceedings of the National Academy of Sciences of the United States of America

    Key finding: These findings demonstrate the cell-to-cell transmission of alpha-synuclein aggregates and provide critical insights into the mechanism of pathological progression in PD and other proteinopathies.

    Full summary, score breakdown and related studies → Original source

  4. 2009-07-26

    Where to declare poor nursing home care

    ✓ Peer-reviewed Health systems and care delivery Journal of vascular surgery

    Key finding: He is known only to have an elderly distant cousin. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2009-07-24

    Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Here, we used aged triple transgenic mice (3xTg-AD) that express pathogenic forms of amyloid precursor protein, presenilin, and tau to investigate the effect of neural stem cell transplantation on AD-related neuropathology and cognitive dysfunction. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2009-07-23

    Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide

    ✓ Peer-reviewed Inflammation and the immune system Neurobiology of aging

    Key finding: We investigated the expression of cystathionine-beta-synthase (CBS) and cystathionine-gamma-lyase (CGL), the two H(2)S synthesizing enzymes, in human cell lines and in human brain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2009-07-22

    The excitotoxin quinolinic acid induces tau phosphorylation in human neurons

    ✓ Peer-reviewed Treatments PloS one

    Key finding: We have previously shown that the KP is over activated in AD brain and that QA accumulates in amyloid plaques and within dystrophic neurons. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2009-07-22

    Astrocytic dysfunction: insights on the role in neurodegeneration

    ✓ Peer-reviewed Inflammation and the immune system Brain research bulletin

    Key finding: Studies of the last 20 years, however, challenged this view by demonstrating that astrocytes possess functional receptors for neurotransmitters and respond to their stimulation via release of gliotransmitters, including glutamate. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2009-07-21

    Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1DeltaE9 mouse model of Alzheimer's disease

    ✓ Peer-reviewed Drug development Molecular psychiatry

    Key finding: In this study, we report that both drugs significantly reduced (1) spatial memory impairment induced by amyloid burden; (2) Abeta aggregates and Abeta oligomers; and (3) astrocytic and microglia activation. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →