alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 21,201–21,225 of 27,380 studies, newest first · page 849 of 1096.

November 2009 6

  1. 2009-11-01

    Hippocampal correlates of pain in healthy elderly adults: a pilot study

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Older adults who report more severe acute or chronic pain have smaller hippocampal volumes and lower levels of hippocampal N-acetylaspartate/creatine, a marker of neuronal integrity. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2009-11-01

    Differences in brain volume, hippocampal volume, cerebrovascular risk factors, and apolipoprotein E4 among mild cognitive impairment subtypes

    ✓ Peer-reviewed Brain scans and imaging Archives of neurology

    Key finding: Amnestic forms of MCI appear to have demographic, genetic, and MRI findings suggestive of Alzheimer disease pathology, whereas the nonamnestic forms of MCI have findings suggestive of vascular disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2009-11-01

    Contribution of chronic diseases to disability in elderly people in countries with low and middle incomes: a 10/66 Dementia Research Group population-based survey

    ✓ Peer-reviewed Getting a diagnosis Lancet (London, England)

    Key finding: When zero inflation was taken into account, between-site differences in disability scores were largely attributable to compositional differences in health and sociodemographic characteristics. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2009-11-01

    The heritability and genetics of frontotemporal lobar degeneration

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: These findings show that frontotemporal lobar degeneration (FTLD) is a highly heritable disorder but heritability varies between the different syndromes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2009-11-01

    Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson disease

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: The Montreal Cognitive Assessment, but not the Mini-Mental State Examination, has adequate psychometric properties as a screening instrument for the detection of mild cognitive impairment or dementia in Parkinson disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2009-11-01

    Clinical syndromes associated with posterior atrophy: early age at onset AD spectrum

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Logopenic progressive aphasia and posterior cortical atrophy showed largely overlapping anatomic and biologic features with early age at onset of Alzheimer disease, suggesting that these clinical syndromes represent the spectrum of clinical manifestation of the nontypical form of Alzheimer disease that presents at an early age. +4 more findings

    Full summary, score breakdown and related studies → Original source

October 2009 19

  1. 2009-10-30

    Olive oil and cognition: results from the three-city study

    ✓ Peer-reviewed Prevention trials Dementia and geriatric cognitive disorders

    Key finding: This olive oil-cognition association needs to be confirmed by further studies. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2009-10-29

    Urine formaldehyde level is inversely correlated to mini mental state examination scores in senile dementia

    ✓ Peer-reviewed Cognitive tests and assessment Neurobiology of aging

    Key finding: Endogenous formaldehyde may be a marker for progressive senile dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2009-10-28

    Memantine versus donepezil in mild to moderate Alzheimer's disease: a randomized trial with magnetic resonance spectroscopy

    ✓ Peer-reviewed Treatments European journal of neurology

    Key finding: Donepezil and memantine have similar modest clinical and spectroscopic effect on mild to moderate AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2009-10-23

    In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP

    ✓ Peer-reviewed Risk genes beyond APOE Free radical biology & medicine

    Key finding: In this study, we show that transgenic mice modeling Alzheimer disease-PDAPP mice with Swedish and Indiana mutations in the human amyloid precursor protein (APP)-develop oxidative damage in brain, including elevated levels of protein oxidation (indexed by protein carbonyls and 3-nitrotyrosine) and lipid peroxidation (indexed by protein-bound 4-hydroxy-2-nonenal). +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2009-10-22

    Total and phosphorylated tau protein as biological markers of Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Experimental gerontology

    Key finding: Clinical research consistently demonstrated CSF t- and p-tau increased in AD compared to controls.

    Full summary, score breakdown and related studies → Original source

  6. 2009-10-21

    Persistent treatment with cholinesterase inhibitors and/or memantine slows clinical progression of Alzheimer disease

    ✓ Peer-reviewed Treatments Alzheimer's research & therapy

    Key finding: There are no empiric data to support guidelines for duration of therapy with antidementia drugs. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2009-10-21

    Chronic disease prevalence and care among the elderly in urban and rural Beijing, China - a 10/66 Dementia Research Group cross-sectional survey

    ✓ Peer-reviewed Disparities BMC public health

    Key finding: Apparent better health in Daxing might be explained by under-diagnosis, under-reporting or selective mortality. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2009-10-21

    Age, Alzheimer disease, and brain structure

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Brain atrophy with aging was observed in supratentorial and infratentorial areas, as well in primary motor, sensory, and heteromodal association regions.

    Full summary, score breakdown and related studies → Original source

  9. 2009-10-19

    Prevalence of dementia and major dementia subtypes in Spanish populations: A reanalysis of dementia prevalence surveys, 1990-2008

    ✓ Peer-reviewed Risk factors BMC Neurology

    Key finding: The reanalyzed study population (aged 70 year and above) was composed of Central and North-Eastern Spanish sub-populations obtained from 9 surveys and totaled 12,232 persons and 1,194 cases of dementia (707 of Alzheimer's disease, 238 of vascular dementia). +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2009-10-17

    Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: two faces of the same coin?

    ✓ Peer-reviewed Digital health tools Neuromolecular medicine

    Key finding: AD is associated with high levels of amyloid-beta (A beta) peptides in the brain, synaptic depression, aberrant excitatory neuronal activity, and cognitive decline.

    Full summary, score breakdown and related studies → Original source

  11. 2009-10-17

    Hastening death in end-of-life care: a survey of doctors

    ✓ Peer-reviewed End-of-life care Social science & medicine (1982)

    Key finding: The application of medical technology to prolong life at the expense of quality of life is widely debated in end-of-life care. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2009-10-16

    Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain

    ✓ Peer-reviewed Drug development Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Abeta peptides are generated when amyloid precursor protein (APP) is cleaved by presenilins, a process that also produces APP intracellular domain (AICD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2009-10-16

    Preclinical properties of 18F-AV-45: a PET agent for Abeta plaques in the brain

    ✓ Peer-reviewed Risk genes beyond APOE Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: Imaging agents targeting the Abeta plaques in the living human brain are potentially valuable as biomarkers of pathogenesis processes in AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2009-10-15

    Oxidative stress caused by ozone exposure induces loss of brain repair in the hippocampus of adult rats

    ✓ Peer-reviewed Biomarkers Toxicological sciences : an official journal of the Society of Toxicology

    Key finding: Our results indicated that ozone causes an increase of LPO levels, morphological changes in the nucleus and the cytoplasm, and cell swelling in neurons. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2009-10-15

    FUS pathology in basophilic inclusion body disease

    ✓ Peer-reviewed Brain tissue and pathology Acta neuropathologica

    Key finding: The normal nuclear expression of TDP-43 is not altered. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2009-10-15

    Amyloid-beta(1-42), total tau, and phosphorylated tau as cerebrospinal fluid biomarkers for the diagnosis of Alzheimer disease

    ✓ Peer-reviewed Tau biomarkers Clinical chemistry

    Key finding: We have used these markers and evaluated their performance. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2009-10-15

    TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration

    ✓ Peer-reviewed Lewy body dementia Proceedings of the National Academy of Sciences of the United States of America

    Key finding: These results indicate that the cellular and molecular substrates for selective vulnerability in FTLD-U and ALS are shared between mice and humans, and suggest that altered DNA/RNA-binding protein function, rather than toxic aggregation, is central to TDP-43-related neurodegeneration.

    Full summary, score breakdown and related studies → Original source

  18. 2009-10-14

    Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly

    ✓ Peer-reviewed Brain scans and imaging Biological psychiatry

    Key finding: Before any manifestations of cognitive or behavioral changes, there were differences in resting state connectivity in cognitively normal subjects with brain amyloid deposition, suggesting that early manifestation of Abeta toxicity can be detected using resting state fMRI. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2009-10-13

    Sustained hippocampal IL-1beta overexpression impairs contextual and spatial memory in transgenic mice

    ✓ Peer-reviewed Down syndrome and Alzheimer's Brain, behavior, and immunity

    Key finding: Neuroinflammatory conditions such as traumatic brain injury, aging, Alzheimer's disease, and Down syndrome are often associated with cognitive dysfunction.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →