Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 26,551–26,575 of 27,380 studies, newest first · page 1063 of 1096.

March 1995 12

  1. 1995-03-01

    Depression and memory impairment: a meta-analysis of the association, its pattern, and specificity

    ✓ Peer-reviewed Risk factors Psychological bulletin

    Key finding: The purpose of this investigation was to determine whether depression is associated with memory impairment, whether moderator variables determine the extent of this association, and whether any obtained association is unique to depression. +1 more finding

  2. 1995-03-01

    Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43)

    ✓ Peer-reviewed Tau biomarkers The Journal of biological chemistry

    Key finding: Immunocytochemical analysis with monoclonal antibodies selective for A beta s ending at A beta 42(43) or A beta 40 confirmed that, in brains with minimal congophilic angiopathy, virtually all A beta is A beta ending at A beta 42(43) and showed that this A beta is deposited in senile plaques of all types. +1 more finding

  3. 1995-03-01
  4. 1995-03-01

    Long-term estrogen replacement therapy in female patients with dementia of the Alzheimer type: 7 case reports

    ✓ Peer-reviewed Cognitive tests and assessment Dementia (Basel, Switzerland)

    Key finding: Five of the 7 patients were cases who had responded well to short-term ERT with 1.25 mg/day of conjugated equine estrogens (CEE) for 6 weeks. +3 more findings

  5. 1995-03-01

    HIV Dementia Scale: a rapid screening test

    ✓ Peer-reviewed Cognitive tests and assessment Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association

    Key finding: Accurate and early diagnosis of HIV dementia can lead to optimized therapeutic and management decisions. +3 more findings

  6. 1995-03-01

    Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B

    ✓ Peer-reviewed Tau biomarkers The Journal of biological chemistry

    Key finding: In this study the dephosphorylation of sparingly soluble PHF, PHF II-tau by brain protein phosphatase (PP)-2A1 and PP-2B, and the resulting biochemical, biological, and structural alterations were investigated. +3 more findings

  7. 1995-03-01

    Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid beta-protein production in human neuronal NT2N cells

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Recent studies have shown that cells can secrete carboxyl terminus truncated APP derivatives (APP-S) in response to physiological stimulus. +3 more findings

  8. 1995-03-01

    Inflammatory processes induce beta-amyloid precursor protein changes in mouse brain

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Factors such as head injury or acute infection that trigger inflammatory processes may play a crucial role in development of the disease. +3 more findings

  9. 1995-03-01

    Progressive multifocal leukoencephalopathy: the evolution of a disease once considered rare

    ✓ Peer-reviewed Caregiving Journal of neurovirology

    Key finding: The clinical features of the disorder in patients with acquired immunodeficiency syndrome do not appear to be significantly different from progressive multifocal leukoencephalopathy occurring in association with other immunosuppressive disorders. +2 more findings

  10. 1995-03-01

    Documentation and evaluation of cognitive impairment in elderly primary care patients

    ✓ Peer-reviewed Getting a diagnosis Annals of internal medicine

    Key finding: Cognitive impairment is associated with increased use of health services and increased mortality. +3 more findings

  11. 1995-03-01

    A severe loss of choline acetyltransferase in the frontal cortex of Alzheimer patients carrying apolipoprotein epsilon 4 allele

    ✓ Peer-reviewed Genetics Neuroscience letters

    Key finding: The ChAT values were significantly lower for the AD patients with 2 epsilon 4 alleles than for those with 0 epsilon 4 (ANOVA, P < 0.05). +3 more findings

  12. 1995-03-01

    Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer disease

    ✓ Peer-reviewed Genetics JAMA

    Key finding: These results suggest that the inheritance of APOE epsilon 4 is associated with reduced cerebral parietal metabolism and increased asymmetry in non-demented relatives at risk for probable AD. +3 more findings

February 1995 6

  1. 1995-02-01

    The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

    ✓ Peer-reviewed Disease mechanisms Neuron

    Key finding: Confocal laser microscopy analysis revealed that anti-NACP immunostaining was colocalized with synaptophysin-immunoreactive presynaptic terminals. +2 more findings

  2. 1995-02-01

    Anterior hippocampal volume deficits in nonamnesic, aging chronic alcoholics

    ✓ Peer-reviewed Hippocampus size on brain scans Alcoholism, clinical and experimental research

    Key finding: The results of this cross-sectional study showed that the anterior, but not the posterior, portions of the hippocampus in both hemispheres were significantly smaller in the alcoholic than the healthy control group. +3 more findings

  3. 1995-02-01

    Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein

    ✓ Peer-reviewed Risk genes beyond APOE Nature

    Key finding: AD brains contain numerous amyloid plaques surrounded by dystrophic neurites, and show profound synaptic loss, neurofibrillary tangle formation and gliosis. +3 more findings

  4. 1995-02-01

    [Alzheimer-type dementia and Down syndrome]

    ✓ Peer-reviewed Down syndrome and Alzheimer's Ugeskrift for laeger

    Key finding: Dementia is seen earlier and more often in patients with Down syndrome (DS) than in the general population. +4 more findings

  5. 1995-02-01

    Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits

    ✓ Peer-reviewed How common it is Journal of neurochemistry

    Key finding: Levels of choline acetyltransferase, acetylcholinesterase, somatostatin, corticotropin-releasing factor, serotonin, and 5-hydroxyindoleacetic acid were significantly reduced in AD versus controls. +2 more findings

  6. 1995-02-01

    Prevalence and subtypes of dementia in Taiwan: a community survey of 5297 individuals

    ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society

    Key finding: The prevalence rate of dementia was low in this Chinese population. +2 more findings

January 1995 7

  1. 1995-01-01

    Autosomal dominant cerebellar phenotypes

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: For these reasons, I suggested in 1990 [1] that for the autosomal dominant phenotypes, the genotype would be required to settle the issue of disease assignment and classification. +4 more findings

  2. 1995-01-01

    Hypomethylation of the amyloid precursor protein gene in the brain of an Alzheimer's disease patient

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of molecular neuroscience : MN

    Key finding: Southern-blot analysis revealed the absence of methylation at a site in the APP gene of an Alzheimer's disease subject. +1 more finding

  3. 1995-01-01

    Corticotropin-releasing factor receptors: physiology, pharmacology, biochemistry and role in central nervous system and immune disorders

    ✓ Peer-reviewed Disease mechanisms Psychoneuroendocrinology

    Key finding: In addition to a physiological role for CRF in integrating the responses of the brain, endocrine and immune systems to physiological, psychological and immunological stimuli, recent clinical data implicate CRF in the etiology and pathophysiology of various endocrine, psychiatric, neurologic and inflammatory illnesses. +4 more findings

  4. 1995-01-01

    Immunoreactivity against tau, amyloid precursor protein, and beta-amyloid in the human retina

    ✓ Peer-reviewed Drug development Investigative ophthalmology & visual science

    Key finding: The proteins investigated in this study are present in the human retina.

  5. 1995-01-01

    Oxidative stress: the paradox of aerobic life

    ✓ Peer-reviewed Brain scans and imaging Biochemical Society symposium

    Key finding: Alternatively, compounds found in certain foods may be able to significantly bolster biological resistance against oxidants.

  6. 1995-01-01

    Alzheimer disease, attention, and the cholinergic system

    ✓ Peer-reviewed Cognitive tests and assessment Alzheimer disease and associated disorders

    Key finding: Recent neuropsychological studies suggest that, in addition to prominent mnemonic dysfunction, attentional impairments are a core feature of Alzheimer disease (AD). +2 more findings

  7. 1995-01-01

    Access to hospice programs in end-stage dementia: a national survey of hospice programs

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: A national survey of hospices revealed that few patients with primary dementia are currently treated by these programs, unless they have other terminal illnesses. +4 more findings

Browse the library by subject, with the full score breakdown →