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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 25,676–25,700 of 27,380 studies, newest first · page 1028 of 1096.

September 1999 13

  1. 1999-09-01

    Soluble Amyloid β Peptide Concentration as a Predictor of Synaptic Change in Alzheimer's Disease

    ✓ Peer-reviewed Disease mechanisms American Journal Of Pathology

    Full summary, score breakdown and related studies → Original source

  2. 1999-09-01

    Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia

    ✓ Peer-reviewed Inflammation and the immune system Annals of neurology

    Key finding: Increased BBB permeability could contribute to the development of dementia by facilitating the entry of activated and infected monocytes, as well as potentially toxic serum proteins, into the central nervous system. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1999-09-01

    HIV-1 Tat induces monocyte chemoattractant protein-1-mediated monocyte transmigration across a model of the human blood-brain barrier and up-regulates CCR5 expression on human monocytes

    ✓ Peer-reviewed Inflammation and the immune system Journal of immunology (Baltimore, Md. : 1950)

    Key finding: A central predictor for clinical onset of these symptoms is the infiltration of monocytes and macrophages into CNS parenchyma. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1999-09-01

    Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neuropathology and experimental neurology

    Key finding: To further explore the potential link between brain trauma and neurodegeneration, we conducted neuropathological studies using a pig model of diffuse brain injury. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1999-09-01

    Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum

    ✓ Peer-reviewed Risk genes beyond APOE American journal of human genetics

    Key finding: EOAD was defined as onset of disease at age <61 years, and ADEOAD was defined as the occurrence of at least three EOAD cases in three generations. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1999-09-01

    Cerebrospinal fluid tau and Abeta42 as predictors of development of Alzheimer's disease in patients with mild cognitive impairment

    ✓ Peer-reviewed Mild cognitive impairment Neuroscience letters

    Key finding: These findings show that these CSF-markers are abnormal before the onset of clinical dementia and that they may help to identify MCI patients that will develop AD.

    Full summary, score breakdown and related studies → Original source

  7. 1999-09-01

    Cervical spine abnormalities in Down Syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Clinical neuropathology

    Key finding: Down Syndrome (DS) is the most common of the chromosomal disorders and manifests abnormalities in several organ systems. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1999-09-01

    Clinical features differentiating patients with postmortem confirmed progressive supranuclear palsy and corticobasal degeneration

    ✓ Peer-reviewed Digital health tools Journal of neurology

    Key finding: Logistic regression analysis identified two sets of predictors (models) for CBD patients, one consisting of asymmetric parkinsonism, cognitive disturbances at onset and instability and falls at first clinic visit, and the other one of asymmetric parkinsonism, cognitive disturbances at symptom onset and speech disturbances. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 1999-09-01

    A randomized trial of risperidone, placebo, and haloperidol for behavioral symptoms of dementia

    ✓ Peer-reviewed How common it is Neurology

    Key finding: Low-dose risperidone (mean 1.1 mg/d) was well tolerated and associated with reductions in the severity and frequency of behavioral symptoms, particularly aggression, in elderly patients with dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 1999-09-01

    Report of the second dementia with Lewy body international workshop: diagnosis and treatment. Consortium on Dementia with Lewy Bodies

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: Clinical management of DLB patients usually centers on the treatment of noncognitive features.

    Full summary, score breakdown and related studies → Original source

  11. 1999-09-01

    The epidemiology of common late-life mental disorders in the community: themes for the new century

    ✓ Peer-reviewed Prevention and risk Psychiatric services (Washington, D.C.)

    Key finding: Attention to three themes may help clinicians and investigators meet the challenge of treating the common mental disorders of later life: the effect of these disorders on functioning, prevention of the consequences of mental disorders, and integration of mental health care and primary health care services. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 1999-09-01

    Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype

    ✓ Peer-reviewed Genetics Free radical biology & medicine

    Key finding: A great number of epidemiological studies have demonstrated that the frequency of the epsilon4 allele of the apolipoprotein E gene (APOE) is markedly higher in sporadic and in familial late onset Alzheimer disease (AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 1999-09-01

    Glial HO-1 expression, iron deposition and oxidative stress in neurodegenerative diseases

    ✓ Peer-reviewed Biomarkers Neurotoxicity research

    Key finding: In rat primary astrocyte cultures, we demonstrated that dopamine, cysteamine, H(2)O(2) and menadione rapidly induce heme oxygenase-1 (HO-1) expression (mRNA and protein) followed by sequestration of non-transferrin-derived (55)Fe by the mitochondrial compartment. +1 more finding

    Full summary, score breakdown and related studies → Original source

August 1999 12

  1. 1999-08-01

    Occurrence and Progression of Dementia in a Community Population Aged 75 Years and Older

    ✓ Peer-reviewed Drug development Archives of Neurology

    Key finding: Subjects taking antihypertensive medication (n = 651, 83.9% of whom took diuretics) had a lower prevalence of dementia than those not taking antihypertensive medication (P<.001). +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1999-08-01

    Cerebral amyloid angiopathy-related hemorrhage. Interaction of APOE epsilon2 with putative clinical risk factors

    ✓ Peer-reviewed Digital health tools Stroke

    Key finding: Our findings suggest that antiplatelet or anticoagulant medication, hypertension, or minor head trauma are most likely to precipitate cerebral hemorrhage in patients with CAA who are also epsilon2 carriers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1999-08-01

    Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects

    ✓ Peer-reviewed Brain tissue and pathology Annals of neurology

    Key finding: In a previous study, we showed that the polymorphic codon 129 of the prion protein gene (PRNP), and two types of protease-resistant prion protein (PrP(Sc)) with distinct physicochemical properties, are major determinants of these variants.

    Full summary, score breakdown and related studies → Original source

  4. 1999-08-01

    The role of copper in neurodegenerative disease

    ✓ Peer-reviewed Brain scans and imaging Neurobiology of disease

    Key finding: Ceruloplasmin contains 95% of the copper found in human plasma and inherited loss of this essential ferroxidase is associated with progressive neurodegeneration of the retina and basal ganglia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1999-08-01

    Drug-induced cognition disorders in the elderly: incidence, prevention and management

    ✓ Peer-reviewed Clinical safety Drug safety

    Key finding: Older antihypertensive agents (reserpine, clonidine) have negative effects on cognition; however, large clinical trials in the elderly indicate that commonly used agents [e.g. thiazide diuretics, calcium antagonists (amiodipine, diltiazem), ACE inhibitors (captopril, enalapril) and beta-blockers (atenolol)] have minimal effects on cognition.

    Full summary, score breakdown and related studies → Original source

  6. 1999-08-01

    Frequency of tau mutations in three series of non-Alzheimer's degenerative dementia

    ✓ Peer-reviewed Disease mechanisms Annals of neurology

    Key finding: Splice-site and missense mutations have been identified in tau associated with frontotemporal dementia with parkinsonism linked to chromosome 17. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 1999-08-01

    Validity and responsiveness of the Minimum Data Set

    ✓ Peer-reviewed Cognitive tests and assessment Journal of the American Geriatrics Society

    Key finding: Cross sectional analysis comparing prospectively collected research data with MDS data reported from nursing homes on identical subjects. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1999-08-01

    Activation of neuronal caspase-3 by intracellular accumulation of wild-type Alzheimer amyloid precursor protein

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Caspase-3 (CPP32) is a principal cell death protease involved in neuronal apoptosis during physiological development and under pathological conditions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 1999-08-01

    Intracellular APP processing and A beta production in Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neuropathology and experimental neurology

    Key finding: A role for A beta in the etiology of AD has been argued from analysis of mutations associated with a subset of early-onset familial AD (FAD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 1999-08-01

    Construct and concurrent validity of the Hopkins Verbal Learning Test-revised

    ✓ Peer-reviewed Lewy body dementia The Clinical neuropsychologist

    Key finding: Group comparisons showed that normal controls performed better than age- and education-matched patients with probable Alzheimer's disease (AD) or vascular dementia (VaD). +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 1999-08-01

    Bilateral contemporaneous posteroventral pallidotomy for the treatment of Parkinson's disease: neuropsychological and neurological side effects. Report of four cases and review of the literature

    ✓ Peer-reviewed Digital health tools Journal of neurosurgery

    Key finding: Despite these good results in the CAPIT scores, one patient experienced a partially regressive corticobulbar syndrome with dysphagia, dysarthria, and increased drooling. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 1999-08-01

    EUROCARE: a cross-national study of co-resident spouse carers for people with Alzheimer's disease: I--Factors associated with carer burden

    ✓ Peer-reviewed Prevention and risk International journal of geriatric psychiatry

    Key finding: There have, however, been few studies which have sought to investigate factors associated with carer burden and differences and similarities between countries. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →