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59/100

✓ Peer-reviewed alzhub usefulness score 59 out of 100. Brain tissue and pathology

Topic: Risk, prevention and care in population studies

Plain-language summary

Background The extent to which specific factors influence diagnostic delays in dementia is unclear. Therefore, the aim of the present study was to compare duration from symptom onset to diagnosis for young-onset dementia (YOD) and late-onset dementia (LOD) and to assess the effect of age at onset, type of dementia, gender, living situation, education and family history of dementia on this duration. Method Data on 235 YOD and 167 LOD patients collected from caregivers from two prospective cohort studies were used.

What this study adds

Evidence grade: Moderate

This is a follow-up (cohort) study. This study compared how long it took to diagnose young-onset versus late-onset dementia and examined factors affecting that delay. It is about diagnosis timing and does not test any treatment, cure or prevention.

Taken from this record’s own fields, not from reading the paper. The grade is assigned from the abstract’s wording; what that means.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

van Vliet, D., de Vugt, M. E., Bakker, C., Pijnenburg, Y. A., Vernooij-Dassen, M. J., Koopmans, R. T., et al. (2013). Time to diagnosis in young-onset dementia as compared with late-onset dementia. Psychological medicine. https://doi.org/10.1017/s0033291712001122

Vancouver

van Vliet D, de Vugt ME, Bakker C, Pijnenburg YA, Vernooij-Dassen MJ, Koopmans RT, et al. Time to diagnosis in young-onset dementia as compared with late-onset dementia. Psychological medicine. 2013. doi:10.1017/s0033291712001122. PMID: 22640548.

BibTeX

@article{vanvliet2013-22640548,
  author  = {van Vliet, D. and de Vugt, M. E. and Bakker, C. and Pijnenburg, Y. A. and Vernooij-Dassen, M. J. and Koopmans, R. T. and Verhey, F. R.},
  title   = {{Time to diagnosis in young-onset dementia as compared with late-onset dementia}},
  journal = {Psychological medicine},
  year    = {2013},
  doi     = {10.1017/s0033291712001122},
  pmid    = {22640548},
  url     = {https://doi.org/10.1017/s0033291712001122}
}

Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.

How to read this study

Design: this is a follow-up (cohort) study. People are observed over time and not assigned to anything, so an association can reflect other differences between groups. Look at how long follow-up lasted, how many dropped out, and whether the authors adjusted for age, education and other health conditions.
Size: the record gives no participant count. Look for one in the original before trusting a pattern.
Effect: the record gives no effect size, so the summary above cannot say how large any difference was.

What the evidence grade means here

This page is graded moderate. alzhub.org assigns the grade automatically from keywords in the abstract, not from reading the paper. Moderate means the abstract mentions a cohort, case-control or longitudinal design. It can add at most 5 of the 100 points in the study score, and it is a label about design, not a verdict on whether the findings are true.

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Key findings

Therefore, the aim of the present study was to compare duration from symptom onset to diagnosis for young-onset dementia (YOD) and late-onset dementia (LOD) and to assess the effect of age at onset, type of dementia, gender, living situation, education and family history of dementia on this duration.
Method Data on 235 YOD and 167 LOD patients collected from caregivers from two prospective cohort studies were used.
Multiple linear regression analysis was performed.
Results The duration between symptom onset and the diagnosis of YOD exceeded that of LOD by an average of 1.6 years (2.8 v. 4.4 years).

Why it matters

This study compared how long it took to diagnose young-onset versus late-onset dementia and examined factors affecting that delay. It is about diagnosis timing and does not test any treatment, cure or prevention.

Study details

Study designcohort study
Evidence strengthModerate

How this study scored 59/100

Published in a peer-reviewed journal, and it is a cohort study following people over time. Scored zero for sample size, effect reported, studied in people and randomized / blinded because the record does not state it.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Psychological medicine)
Journal's citation record	3 / 4	Psychological Medicine: journal h-index 331 (OpenAlex, 2026-10-29)
Study design	7 / 12	A cohort study following people over time
Strength of evidence	3 / 5	Rated “moderate” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	1 / 5	2013 — within 20 year(s) of the newest study here
Sample size	0 / 4	Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	0 / 3	Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomized / blinded	0 / 2	No randomization or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	6 / 7	Cited 308 times (OpenAlex, 2026-10-10)
Citations per year	4 / 5	20.5 citations a year over 15 year(s) since 2013
Impact for its field and year	3 / 6	Cited 5.5× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	3 / 6	Cited by 18 other studies in this library
Still being cited	3 / 4	Cited 110 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	4 / 4	Last-listed author Frans R.J. Verhey: h-index 111 (OpenAlex, whole career)
Institution's track record	1 / 3	Radboud University Nijmegen: institution h-index 1,143 (OpenAlex)
Multicenter collaboration	2 / 3	OpenAlex lists 4 institution(s) in 1 country
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 22640548)
Free to read	0 / 2	Behind a paywall — scores zero
Total	59 / 100	—

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