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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,551–19,575 of 27,380 studies, newest first · page 783 of 1096.

April 2012 14

  1. 2012-04-01

    Central cardiovascular circuits contribute to the neurovascular dysfunction in angiotensin II hypertension

    ✓ Peer-reviewed Clinical safety The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: The SFO mediates the dysfunction via two signaling pathways. +4 more findings

  2. 2012-04-01

    Obstructive sleep apnea and incidence of postoperative delirium after elective knee replacement in the nondemented elderly

    ✓ Peer-reviewed Clinical safety Anesthesiology

    Key finding: This is the first prospective study employing validated measures of delirium to identify an association between preexisting obstructive sleep apnea and postoperative delirium. +4 more findings

  3. 2012-04-01

    Mediterranean diet and longevity in Sicily: survey in a Sicani Mountains population

    ✓ Peer-reviewed Prevention trials Rejuvenation research

    Key finding: Over the past several years, increasing evidence suggests that the Mediterranean diet has a beneficial influence on several age-related diseases, showing protective effect on health and longevity. +1 more finding

  4. 2012-04-01

    Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo

    ✓ Peer-reviewed Disease mechanisms Autophagy

    Key finding: Incubation with nanomolar concentrations of MB was sufficient to significantly reduce levels of tau both in organotypic brain slice cultures from a mouse model of FTD, and in cell models. +2 more findings

  5. 2012-04-01

    Symptoms of rapid eye movement sleep behavior disorder are associated with cholinergic denervation in Parkinson disease

    ✓ Peer-reviewed Cognitive tests and assessment Annals of neurology

    Key finding: Rapid eye movement sleep behavior disorder (RBD) is common in Parkinson disease (PD), but its relationship to the varied neurotransmitter deficits of PD and prognostic significance remain incompletely understood. +3 more findings

  6. 2012-04-01

    Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model

    ✓ Peer-reviewed Risk genes beyond APOE Cell

    Key finding: We studied human amyloid precursor protein (hAPP) transgenic mice, which simulate key aspects of AD. +3 more findings

  7. 2012-04-01

    The neuropsychological profile of Alzheimer disease

    ✓ Peer-reviewed Lewy body dementia Cold Spring Harbor perspectives in medicine

    Key finding: Neuropsychological assessment has featured prominently over the past 30 years in the characterization of dementia associated with Alzheimer disease (AD).

  8. 2012-04-01

    Fecal corticosterone levels in RCAN1 mutant mice

    ✓ Peer-reviewed Down syndrome and Alzheimer's Comparative medicine

    Key finding: We found no difference in fecal corticosterone levels of RCAN1-knockout mice and their wildtype littermates. +2 more findings

  9. 2012-04-01

    Brain imaging in Alzheimer disease

    ✓ Peer-reviewed Getting a diagnosis Cold Spring Harbor perspectives in medicine

    Key finding: Initially, computed tomography (CT) and then magnetic resonance imaging (MRI) were used diagnostically to rule out other causes of dementia. +4 more findings

  10. 2012-04-01

    Accuracy of the clinical diagnosis of Alzheimer disease at National Institute on Aging Alzheimer Disease Centers, 2005-2010

    ✓ Peer-reviewed Getting a diagnosis Journal of neuropathology and experimental neurology

    Key finding: Sensitivity was generally increased with more permissive clinical criteria and specificity was increased with more restrictive criteria, whereas the opposite was true for neuropathologic criteria. +4 more findings

  11. 2012-04-01

    The antipsychotic discontinuation in Alzheimer disease trial: clinical rationale and study design

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: This study will provide clinically relevant data on the likelihood and time to relapse, and predictors of relapse, in patients switched from risperidone to placebo after response to risperidone treatment. +1 more finding

  12. 2012-04-01

    Effects of Chinese medicine for tonifying the kidney and resolving phlegm and blood stasis in treating patients with amnestic mild cognitive impairment: a randomized, double-blind and parallel-controlled trial

    ✓ Peer-reviewed Treatments Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine

    Key finding: Studies have shown that donepezil could reduce the AD assessment scale-cognitive subscale (ADAS-Cog) score in MCI patients and improve the patient's attention and speed of response; however, it also has many side effects. +2 more findings

  13. 2012-04-01

    Three-week nutritional supplementation effect on long-term nutritional status of patients with mild Alzheimer disease

    ✓ Peer-reviewed Treatments Alzheimer disease and associated disorders

    Key finding: Intervention resulted in significant improvements in Mini Nutritional Assessment (MNA) score [Mean=1.4, standard deviation (SD)=0.8 vs. 0.0 (0.1) in the control group, P<0.001] and also in anthropometrical and serum biomarkers of Alzheimer disease (AD) patients' nutritional status. +1 more finding

  14. 2012-04-01

    Recruitment strategies for preventive trials. The MAPT study (MultiDomain Alzheimer Preventive Trial)

    ✓ Peer-reviewed Treatments The journal of nutrition, health & aging

    Key finding: Interestingly, the higher percentage of randomizations compared to screened participants is the personal contact source; almost 85 % of screened participants entered in the study.

March 2012 11

  1. 2012-03-30

    NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain

    ✓ Peer-reviewed Brain scans and imaging NeuroImage

    Key finding: This paper introduces neurite orientation dispersion and density imaging (NODDI), a practical diffusion MRI technique for estimating the microstructural complexity of dendrites and axons in vivo on clinical MRI scanners.

  2. 2012-03-30

    Elevated oxidative stress and decreased antioxidant function in the human hippocampus and frontal cortex with increasing age: implications for neurodegeneration in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Neurochemical research

    Key finding: Previously, we demonstrated increased oxidative damage and lowered antioxidant function in substantia nigra during aging making it vulnerable to degeneration associated with Parkinson's disease. +4 more findings

  3. 2012-03-30

    Teaching an adult brain new tricks: a critical review of evidence for training-dependent structural plasticity in humans

    ✓ Peer-reviewed Hippocampus size on brain scans NeuroImage

    Key finding: A growing number of structural neuroimaging studies have reported significant changes in gray matter density or volume and white matter microstructure in the adult human brain following training. +1 more finding

  4. 2012-03-29

    Trans-cellular propagation of Tau aggregation by fibrillar species

    ✓ Peer-reviewed Lewy body dementia The Journal of biological chemistry

    Key finding: Aggregation of the microtubule associated protein Tau is associated with several neurodegenerative disorders, including Alzheimer disease and frontotemporal dementia. +1 more finding

  5. 2012-03-28

    Metformin, other antidiabetic drugs, and risk of Alzheimer's disease: a population-based case-control study

    ✓ Peer-reviewed Getting a diagnosis Journal of the American Geriatrics Society

    Key finding: Long-term use of sulfonylureas, thiazolidinediones, or insulin was not associated with an altered risk of developing AD. +2 more findings

  6. 2012-03-28

    Effects of lexical-semantic treatment on memory in early Alzheimer disease: an observer-blinded randomized controlled trial

    ✓ Peer-reviewed Treatments Neurorehabilitation and neural repair

    Key finding: LSS treatment may improve episodic memory in AD patients and may be regarded as a clinical option to counteract the cognitive decline typical of the disease. +1 more finding

  7. 2012-03-23

    Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis

    ✓ Peer-reviewed Drug development BMC neuroscience

    Key finding: Our results suggest that these novel incretin analogues cross the BBB and show physiological activity and neurogenesis in the brain, which may be of use as a treatment of neurodegenerative diseases. +2 more findings

  8. 2012-03-23

    Longitudinal imaging of Alzheimer pathology using [11C]PIB, [18F]FDDNP and [18F]FDG PET

    ✓ Peer-reviewed Mild cognitive impairment European journal of nuclear medicine and molecular imaging

    Key finding: A significant increase in global cortical [(11)C]PIB BP(ND) was found in MCI patients, but no changes were observed in AD patients or controls. +2 more findings

  9. 2012-03-22

    Predicting future clinical changes of MCI patients using longitudinal and multimodal biomarkers

    ✓ Peer-reviewed Mild cognitive impairment PloS one

    Key finding: The results on both sets of experiments show that our proposed method can achieve better performance in predicting future clinical changes of MCI patients than the conventional methods.

  10. 2012-03-21

    Defining Alzheimer as a common age-related neurodegenerative process not inevitably leading to dementia

    ✓ Peer-reviewed Mild cognitive impairment Progress in neurobiology

    Key finding: The concepts derived from the β-amyloid hypothesis support β-amyloid as a conductor in the pathogenesis of familial AD and as a prodding factor in sporadic AD. +4 more findings

  11. 2012-03-21

    Prefrontal cortex rTMS enhances action naming in progressive non-fluent aphasia

    ✓ Peer-reviewed Digital health tools European journal of neurology

    Key finding: Our study demonstrated that rTMS improved action naming in subjects with PNFA, possibly due to the modulation of DLPFC pathways and a facilitation effect on lexical retrieval processes. +2 more findings

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