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Excessive sleepiness is predictive of cognitive decline in the elderly
Jaussent I, Bouyer J, Ancelin ML, Berr C, Foubert-Samier A, Ritchie K, Ohayon MM, Besset A et al.. Sleep, 2012-09-01
Topic: Risk, prevention and care in population studies
Study objectives To examine the association of sleep complaints reported at baseline (insomnia complaints and excessive daytime sleepiness (EDS)) and medication, with cognitive decline in community-dwelling elderly. Participants There were 4,894 patients without dementia recruited from 3 French cities and having a Mini-Mental Status Examination (MMSE) score ≥ 24 points at baseline. Measurements and results Questionnaires were used to evaluate insomnia complaints (poor sleep quality (SQ), difficulty in initiating sleep (DIS), difficulty in maintaining sleep (DMS), early morning awakening (EMA)), EDS, and sleep medication at baseline.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Jaussent, I., Bouyer, J., Ancelin, M. L., Berr, C., Foubert-Samier, A., Ritchie, K., et al. (2012). Excessive sleepiness is predictive of cognitive decline in the elderly. Sleep. https://doi.org/10.5665/sleep.2070
Vancouver
Jaussent I, Bouyer J, Ancelin ML, Berr C, Foubert-Samier A, Ritchie K, et al. Excessive sleepiness is predictive of cognitive decline in the elderly. Sleep. 2012. doi:10.5665/sleep.2070. PMID: 22942498.
BibTeX
@article{jaussent2012-22942498,
author = {Jaussent, I. and Bouyer, J. and Ancelin, M. L. and Berr, C. and Foubert-Samier, A. and Ritchie, K. and Ohayon, M. M. and Besset, A. and others},
title = {{Excessive sleepiness is predictive of cognitive decline in the elderly}},
journal = {Sleep},
year = {2012},
doi = {10.5665/sleep.2070},
pmid = {22942498},
url = {https://doi.org/10.5665/sleep.2070}
}
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Key findings
- Participants There were 4,894 patients without dementia recruited from 3 French cities and having a Mini-Mental Status Examination (MMSE) score ≥ 24 points at baseline.
- Measurements and results Questionnaires were used to evaluate insomnia complaints (poor sleep quality (SQ), difficulty in initiating sleep (DIS), difficulty in maintaining sleep (DMS), early morning awakening (EMA)), EDS, and sleep medication at baseline.
- Cognitive decline was defined as a 4-point reduction in MMSE score during follow-up at 2, 4, and 8 yr.
- Logistic regression models were adjusted for sociodemographic, behavioral, physical, and mental health variables, and apolipoprotein E genotype.
Why it matters
In 4,894 older people without dementia, excessive daytime sleepiness reported at the start predicted later cognitive decline on the Mini-Mental State Examination. This shows an association only and does not show that treating sleepiness prevents or cures Alzheimer's disease.
Study details
- Study designlongitudinal study
- Participants4,894
- Effect sizeOR = 1.39; OR = 0.77; OR = 0.81
- Evidence strengthModerate
How this study scored 68/100
Published in a peer-reviewed journal, and it is a longitudinal study following the same people over time. Scored zero for randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Sleep) |
| Journal's citation record | 3 / 4 | SLEEP: journal h-index 308 (OpenAlex, 2026-10-29) |
| Study design | 7 / 12 | A longitudinal study following the same people over time |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2012 — within 20 year(s) of the newest study here |
| Sample size | 3 / 4 | 4,894 participants |
| Effect reported | 3 / 3 | Effect reported with a statistic (interval, p-value, ratio or similar) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 232 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 14.5 citations a year over 16 year(s) since 2012 |
| Impact for its field and year | 5 / 6 | Cited 20.7× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 5 other studies in this library |
| Still being cited | 2 / 4 | Cited 43 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Yves A Dauvilliers: h-index 105 (OpenAlex, whole career) |
| Institution's track record | 3 / 3 | Stanford University: institution h-index 2,684 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 9 institution(s) in 3 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 22942498) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 68 / 100 | — |
What each of these 20 components measures, and what this score is not →
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