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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,976–20,000 of 27,380 studies, newest first · page 800 of 1096.

August 2011 25

  1. 2011-08-16

    Functional connectivity tracks clinical deterioration in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Neurobiology of aging

    Key finding: Our results showed decreased connectivity at baseline in patients versus controls in the posterior default mode network, and increased connectivity in the anterior and ventral default mode networks. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2011-08-16

    A mitochondrial etiology of Alzheimer and Parkinson disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Biochimica et biophysica acta

    Key finding: AD, DS, and DSAD brains also have reduced mtDNA ND6 mRNA levels, altered mtDNA copy number, and perturbed Aβ metabolism.

    Full summary, score breakdown and related studies → Original source

  3. 2011-08-15

    Larger amygdala but no change in hippocampal volume in 10-year-old children exposed to maternal depressive symptomatology since birth

    ✓ Peer-reviewed Hippocampus size on brain scans Proceedings of the National Academy of Sciences of the United States of America

    Key finding: However, children reared in orphanages present enlarged amygdala volumes, suggesting that the amygdala may be particularly sensitive to severely disturbed (i.e., discontinous, neglectful) care in infancy. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2011-08-12

    Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression

    ✓ Peer-reviewed Disease mechanisms The Journal of biological chemistry

    Key finding: The development of this pathology is consistently associated with progressive neuronal loss and cognitive decline. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2011-08-11

    Discovery of sexual dimorphisms in metabolic and genetic biomarkers

    ✓ Peer-reviewed Genetics PLoS genetics

    Key finding: A linear regression approach revealed significant concentration differences between males and females for 102 out of 131 metabolites (p-values<3.8×10(-4); Bonferroni-corrected threshold). +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2011-08-11

    Baseline and longitudinal increases in diastolic blood pressure are associated with greater white matter hyperintensity volume: the northern Manhattan study

    ✓ Peer-reviewed Disparities Stroke

    Key finding: Baseline DBP and longitudinal increases in DBP were independently associated with a greater WMHV, and the association between DBP and WMHV was greatest among blacks. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2011-08-11

    The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study

    ✓ Peer-reviewed Getting a diagnosis Journal of neurology, neurosurgery, and psychiatry

    Key finding: Co-morbid dementia occurs in approximately 14% of patients with a new diagnosis of ALS. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2011-08-08

    Evidence for ordering of Alzheimer disease biomarkers

    ✓ Peer-reviewed Tau biomarkers Archives of neurology

    Key finding: A total of 401 elderly participants in the Alzheimer's Disease Neuroimaging Initiative who were cognitively normal, who had mild cognitive impairment, or who had AD dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2011-08-05

    Psychometric properties of instruments to measure the quality of end-of-life care and dying for long-term care residents with dementia

    ✓ Peer-reviewed End-of-life care Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

    Key finding: Our comparative study of psychometric properties of instruments allows for informed selection of QOC and QOD measures for LTC residents with dementia.

    Full summary, score breakdown and related studies → Original source

  10. 2011-08-04

    Exercise training increases mitochondrial biogenesis in the brain

    ✓ Peer-reviewed Prevention trials Journal of applied physiology (Bethesda, Md. : 1985)

    Key finding: These findings suggest that exercise training increases brain mitochondrial biogenesis, which may have important implications, not only with regard to fatigue, but also with respect to various central nervous system diseases and age-related dementia that are often characterized by mitochondrial dysfunction.

    Full summary, score breakdown and related studies → Original source

  11. 2011-08-04

    Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria

    ✓ Peer-reviewed Brain tissue and pathology Journal of neuroinflammation

    Key finding: Recently it has been suggested that various types of spirochetes, in an analogous way to Treponema pallidum, could cause dementia and may be involved in the pathogenesis of Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2011-08-03

    Resting state fMRI in Alzheimer's disease: beyond the default mode network

    ✓ Peer-reviewed Brain scans and imaging Neurobiology of aging

    Key finding: Compared with controls and aMCI, AD was associated with opposing connectivity effects in the DMN (decreased) and frontal networks (enhanced). +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2011-08-02

    Understanding the role of TDP-43 and FUS/TLS in ALS and beyond

    ✓ Peer-reviewed Brain tissue and pathology Current opinion in neurobiology

    Key finding: TDP-43 and FUS/TLS have striking structural and functional similarities, implicating alterations in RNA processing as central in ALS. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2011-08-02

    Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

    ✓ Peer-reviewed Getting a diagnosis Brain : a journal of neurology

    Key finding: Patients who failed to meet revised criteria were significantly older and most had atypical presentations with marked memory impairment. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2011-08-01

    Cohort Profile: The Irish Longitudinal Study on Ageing

    ✓ Peer-reviewed Risk factors International Journal of Epidemiology

    Key finding: The study has been harmonized with leading international research so as to ensure adoption of best practice and comparability of results. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2011-08-01

    Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation

    ✓ Peer-reviewed Disease mechanisms Molecular aspects of medicine

    Key finding: For the past 40 years or so, oxidative stress has been increasingly recognized as a contributing factor in aging and in various forms of pathophysiology generally associated with aging. +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2011-08-01

    Docosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer's, and other neurodegenerative diseases

    ✓ Peer-reviewed Prevention and risk Annual review of nutrition

    Key finding: This review discusses DHA signalolipidomics, comprising the cellular/tissue organization of DHA uptake, its distribution among cellular compartments, the organization and function of membrane domains rich in DHA-containing phospholipids, and the cellular and molecular events revealed by the uncovering of signaling pathways regulated by DHA and docosanoids, the DHA-derived bioactive lipids, which include neuroprotectin D1 (NPD1), a novel DHA-derived stereoselective mediator.

    Full summary, score breakdown and related studies → Original source

  18. 2011-08-01

    Diabetes as a risk factor for Alzheimer's disease: insulin signalling impairment in the brain as an alternative model of Alzheimer's disease

    ✓ Peer-reviewed Drug development Biochemical Society transactions

    Key finding: These results show that these growth factors activate similar cell signalling mechanisms that are protective and regenerative, and suggest that the initial process that may trigger the cascade of neurodegenerative events in AD could be the impairment of growth factor signalling such as early insulin receptor desensitization.

    Full summary, score breakdown and related studies → Original source

  19. 2011-08-01

    The dynamics of cortical and hippocampal atrophy in Alzheimer disease

    ✓ Peer-reviewed Hippocampus size on brain scans Archives of neurology

    Key finding: Alzheimer disease-specific cortical thinning and hippocampal volume loss are consistent with a sigmoidal pattern, with an acceleration phase during the early stages of the disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2011-08-01

    Usefulness of acute delirium as a predictor of adverse outcomes in patients >65 years of age with acute decompensated heart failure

    ✓ Peer-reviewed Clinical safety The American journal of cardiology

    Key finding: Delirious patients (total n = 151) had an increased in-hospital all-cause death compared to nondelirious patients (n = 17, 11%, vs n = 45, 6%; adjusted odds ratio [OR] 1.93, 95% confidence interval [CI] 1.07 to 3.48, p = 0.02). +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2011-08-01

    Systemic inflammation and delirium: important co-factors in the progression of dementia

    ✓ Peer-reviewed Clinical safety Biochemical Society transactions

    Key finding: This profound and acute exacerbation of cognitive dysfunction is associated with poor prognosis: accelerating cognitive decline and shortening time to permanent institutionalization and death. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2011-08-01

    Mediterranean diet in predementia and dementia syndromes

    ✓ Peer-reviewed Prevention trials Current Alzheimer research

    Key finding: Only recently higher adherence to a Mediterranean-type diet was associated with decreased cognitive decline although the Mediterranean diet (MeDi) combines several foods, micro- and macronutrients already separately proposed as potential protective factors against dementia and predementia syndromes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2011-08-01

    Tyrosol and hydroxytyrosol, two main components of olive oil, protect N2a cells against amyloid-β-induced toxicity. Involvement of the NF-κB signaling

    ✓ Peer-reviewed Prevention trials Current Alzheimer research

    Key finding: Several studies have reported that adherence to the Mediterranean diet (MeDi) was associated with a reduction in incident of dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2011-08-01

    Rosiglitazone does not improve cognition or global function when used as adjunctive therapy to AChE inhibitors in mild-to-moderate Alzheimer's disease: two phase 3 studies

    ✓ Peer-reviewed Cognitive tests and assessment Current Alzheimer research

    Key finding: Two phase 3 studies evaluated the efficacy and safety of rosiglitazone (RSG), a type 2 diabetes treatment, in an extended release (RSG XR) form as adjunctive therapy to ongoing acetylcholine esterase inhibitor (AChEI) treatment in AD (REFLECT-2, adjunctive to donepezil; REFLECT-3, to any AChEI). +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2011-08-01

    Retinal amyloid peptides and complement factor H in transgenic models of Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE Neuroreport

    Key finding: In this report, we have studied the levels of βAPP, Aβ40 and Aβ42 peptide, as well as the innate immune and inflammatory response-regulator complement factor H in the brain and retina in four different Tg-AD models including Tg2576, PSAPP, 3xTg-AD, and 5xFAD. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →