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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 16,226–16,250 of 27,380 studies, newest first · page 650 of 1096.

March 2016 25

  1. 2016-03-16

    Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases

    ✓ Peer-reviewed Getting a diagnosis Neuropharmacology

    Key finding: Dysregulated KP metabolism has been strongly associated with neurological diseases in recent years, and is the subject of increasing efforts to understand how the metabolites are causative of disease pathology.

    Full summary, score breakdown and related studies → Original source

  2. 2016-03-16

    Better verbal memory in women than men in MCI despite similar levels of hippocampal atrophy

    ✓ Peer-reviewed Genetics Neurology

    Key finding: This advantage may represent a sex-specific form of cognitive reserve delaying verbal memory decline until more advanced disease stages.

    Full summary, score breakdown and related studies → Original source

  3. 2016-03-15

    Aging and Neurodegeneration: A Tangle of Models and Mechanisms

    ✓ Peer-reviewed Disease mechanisms Aging and disease

    Key finding: However, the results have so far not been translated to actual benefit for the patients in terms of treatment or diagnosis of age-related degenerative diseases including those of the CNS. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2016-03-15

    Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease

    ✓ Peer-reviewed Genetics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: We confirm that variation in/near APOE/TOMM40 (P = 6 × 10(-14)) alters PCA risk, but with smaller effect than for typical AD (PCA: odds ratio [OR] = 2.03, typical AD: OR = 2.83, P = .0007). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2016-03-15

    Role of oxidative stress in Alzheimer's disease

    ✓ Peer-reviewed Brain tissue and pathology Biomedical reports

    Key finding: This imbalance can occur as a result of increased free radicals or a decrease in antioxidant defense, free radicals being a species that contains one or more unpaired electrons in its outer shell.

    Full summary, score breakdown and related studies → Original source

  6. 2016-03-15

    Altered Proteins in the Aging Brain

    ✓ Peer-reviewed Disease mechanisms Journal of neuropathology and experimental neurology

    Key finding: Intermediate Alzheimer disease-related pathology (ADRP) was seen in 12%; 52% of the subjects with HPτ-IR fulfilled criteria for definite primary age-related tauopathy (PART). +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2016-03-15

    Early and protective microglial activation in Alzheimer's disease: a prospective study using 18F-DPA-714 PET imaging

    ✓ Peer-reviewed Inflammation and the immune system Brain : a journal of neurology

    Key finding: We aimed to study microglial activation in early Alzheimer's disease and its impact on clinical progression using a second-generation 18-kDa translocator protein positron emission tomography radiotracer together with amyloid imaging using Pittsburgh compound B positron emission tomography. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2016-03-14

    Hydrogen Proton Magnetic Resonance Spectroscopy in Multidomain Amnestic Mild Cognitive Impairment and Vascular Cognitive Impairment Without Dementia

    ✓ Peer-reviewed Prevention trials American journal of Alzheimer's disease and other dementias

    Key finding: Compared with the normal control group, the NAA-Cr ratio in all regions studied was significantly lower in the M-aMCI and VCIND groups. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2016-03-14

    Defeating Alzheimer's disease and other dementias: a priority for European science and society

    ✓ Peer-reviewed Health systems and care delivery The Lancet Neurology

    Full summary, score breakdown and related studies → Original source

  10. 2016-03-14

    The frontotemporal dementia-motor neuron disease continuum

    ✓ Peer-reviewed Getting a diagnosis Lancet (London, England)

    Key finding: Early reports of cognitive and behavioural deficits in motor neuron disease might have been overlooked initially, but the concept of a frontotemporal dementia-motor neuron disease continuum has emerged during the past decade. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2016-03-12

    Dysfunction of NMDA receptors in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    Key finding: NMDARs activation has been recently implicated in Alzheimer's disease (AD) related to synaptic dysfunction. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2016-03-11

    Interventions for preventing delirium in hospitalised non-ICU patients

    ✓ Peer-reviewed Prevention and risk The Cochrane database of systematic reviews

    Key finding: Main results We included 39 trials that recruited 16,082 participants, assessing 22 different interventions or comparisons. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2016-03-10

    Context, mechanisms and outcomes in end of life care for people with advanced dementia

    ✓ Peer-reviewed End-of-life care BMC palliative care

    Key finding: Contextual factors regarding the care home environment may be obdurate and tend to negatively impact on the quality of end of life dementia care.

    Full summary, score breakdown and related studies → Original source

  14. 2016-03-10

    Periodontitis and Cognitive Decline in Alzheimer's Disease

    ✓ Peer-reviewed How common it is PloS one

    Key finding: Elevated antibodies to periodontal bacteria are associated with an increased systemic pro-inflammatory state. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2016-03-09

    Diabetes and Alzheimer's disease crosstalk

    ✓ Peer-reviewed End-of-life care Neuroscience and biobehavioral reviews

    Key finding: Interestingly, recent epidemiological studies indicate that diabetes significantly increases the risk of developing AD, suggesting that diabetes may play a causative role in the development of AD pathogenesis.

    Full summary, score breakdown and related studies → Original source

  16. 2016-03-09

    The role of glial-specific Kir4.1 in normal and pathological states of the CNS

    ✓ Peer-reviewed Inflammation and the immune system Acta neuropathologica

    Key finding: In glia, Kir4.1 is implicated in several functions including extracellular K(+) homeostasis, maintenance of astrocyte resting membrane potential, cell volume regulation, and facilitation of glutamate uptake. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2016-03-08

    Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer’s disease

    ✓ Peer-reviewed Brain scans and imaging Brain

    Key finding: Voxel-wise contrasts against controls (at P < 0.05 family-wise error corrected) showed that (18)F-AV1451 and (18)F-FDG patterns in patients with posterior cortical atrophy ('visual variant of Alzheimer's disease', n = 7) specifically targeted the clinically affected posterior brain regions, while (11)C-PiB bound diffusely throughout the neocortex. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2016-03-08

    Age, APOE and sex: Triad of risk of Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment The Journal of steroid biochemistry and molecular biology

    Key finding: Evidence indicates that the APOE-ε4 risk for AD is greater in women than men, which is particularly evident in heterozygous women carrying one APOE-ε4 allele.

    Full summary, score breakdown and related studies → Original source

  19. 2016-03-08

    Insomnia and risk of dementia in older adults: Systematic review and meta-analysis

    ✓ Peer-reviewed Prevention and risk Journal of psychiatric research

    Key finding: However, there are no consensus by means of longitudinal studies data on the increased risk of developing dementia related to insomnia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2016-03-08

    Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease

    ✓ Peer-reviewed Laboratory science Brain

    Key finding: Tau-PET uptake was strongly linked to local loss of brain glucose metabolism (r=-0.49), a marker of neurodegeneration +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2016-03-07

    microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration

    ✓ Peer-reviewed TREM2 and immune genetics PloS one

    Key finding: The triggering receptor expressed in myeloid/microglial cells-2 (TREM2), a trans-membrane-spanning, sensor-receptor of the immune-globulin/lectin-like gene superfamily is a critical component of Aβ42-peptide clearance. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2016-03-06

    Shared decision‐making on a ‘life‐and‐care plan’ in long‐term care facilities: research protocol

    ✓ Peer-reviewed Health systems and care delivery Nursing Open

    Key finding: Shared decision-making is defined as a process where healthcare professionals and patients make decisions together, using the best available evidence. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2016-03-03

    The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Molecular neurodegeneration

    Key finding: mRNA for inflammasome components (NLRP1, NLRP3, PYCARD, caspase 1, 5 and 8) and downstream effectors (IL-1β, IL-18) was up-regulated in severe and MILD AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2016-03-03

    Circadian Rhythms, Sleep, and Disorders of Aging

    ✓ Peer-reviewed Risk factors Trends in endocrinology and metabolism: TEM

    Key finding: These findings are now supported by data from animal models for some of these disorders, raising the question of whether the disrupted sleep/circadian regulation contributes to the loss of neural function.

    Full summary, score breakdown and related studies → Original source

  25. 2016-03-03

    The Lateralization of Intrinsic Networks in the Aging Brain Implicates the Effects of Cognitive Training

    ✓ Peer-reviewed Prevention trials Frontiers in aging neuroscience

    Key finding: We observed statically significant training effects on the lateralization of two important RSNs related to high-level cognition: right- and left- frontoparietal networks (FPNs). +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →