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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,451–12,475 of 27,380 studies, newest first · page 499 of 1096.

September 2019 25

  1. 2019-09-27

    Plasma neurofilament light associates with Alzheimer's disease metabolic decline in amyloid-positive individuals

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: These findings indicate that plasma NfL is a proxy for neurodegeneration in AD-related regions in Aβ+ subjects. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2019-09-27

    Plasma Aβ42 and Total Tau Predict Cognitive Decline in Amnestic Mild Cognitive Impairment

    ✓ Peer-reviewed Tau biomarkers Scientific reports

    Key finding: The current study investigated the abilities of plasma Aβ42 and total-tau (t-tau) levels in predicting cognitive decline in subjects with amnestic mild cognitive impairment (MCI). +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2019-09-27

    Astrocytes: Role and Functions in Brain Pathologies

    ✓ Peer-reviewed Biomarkers Frontiers in pharmacology

    Key finding: In particular, the loss of astrocytes function as a result of cellular senescence could have implications for the neurodegenerative disorders, such as Alzheimer disease and Huntington disease, and for the aging brain.

    Full summary, score breakdown and related studies → Original source

  4. 2019-09-26

    Economic burden for Alzheimer's disease in China from 2010 to 2050: a modelling study

    ✓ Peer-reviewed Costs and economics Journal of market access & health policy

    Key finding: The costs of AD were estimated to be from around 91 billion RMB in 2010 to 332 billion in 2050. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-09-26

    Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

    ✓ Peer-reviewed Disease mechanisms Cell

    Key finding: Alzheimer disease (AD) is a heterogeneous disease with a complex pathobiology. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2019-09-26

    Companion robots for older people: importance of user-centred design demonstrated through observations and focus groups comparing preferences of older people and roboticists in South West England

    ✓ Peer-reviewed Digital health tools BMJ open

    Key finding: The observed misalignment of opinion between end users and developers on desirable design features of companion robots demonstrates the need for user-centred design during development.

    Full summary, score breakdown and related studies → Original source

  7. 2019-09-26

    GWAS Identifies 44 Independent Associated Genomic Loci for Self-Reported Adult Hearing Difficulty in UK Biobank

    ✓ Peer-reviewed Prevention and risk American journal of human genetics

    Key finding: Forty-four independent genome-wide significant loci (p < 5E-08) were identified, considerably increasing the number of established trait loci. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2019-09-25

    APP, PSEN1, and PSEN2 Mutations in Asian Patients with Early-Onset Alzheimer Disease

    ✓ Peer-reviewed Risk genes beyond APOE International journal of molecular sciences

    Key finding: Comparison of AD-causative point mutations in Asian countries; our findings explained only a small fraction of patients, leaving approximately 84% (p = 0.01) of autosomal dominant pedigrees genetically unexplained. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2019-09-25

    Maintaining Social Connections in Dementia: A Qualitative Synthesis

    ✓ Peer-reviewed Digital health tools Qualitative health research

    Key finding: The clinical symptoms of dementia include difficulty with speech, poor short-term memory, and changes in behavior.

    Full summary, score breakdown and related studies → Original source

  10. 2019-09-24

    Small Vessel Disease

    ✓ Peer-reviewed Vascular contributions Frontiers in neurology

    Key finding: Data suggest that when this condition is evident in any organ, it is already systemic in its occurrence and consequences. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2019-09-23

    Microbiome Influence in the Pathogenesis of Prion and Alzheimer's Diseases

    ✓ Peer-reviewed Disease mechanisms International journal of molecular sciences

    Key finding: Mutations in both PrPC and Aβ precursor protein (APP), have been associated with the pathogenesis of these fatal disorders with clear evidence for their pathogenic significance.

    Full summary, score breakdown and related studies → Original source

  12. 2019-09-23

    The role of TREM2 in Alzheimer's disease; evidence from transgenic mouse models

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: A synthesis of the 35 mouse-model studies included in this review indicates that TREM2 modulates amyloid plaque composition and deposition, microglial morphology and proliferation, neuroinflammation, and tau phosphorylation. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2019-09-23

    Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors

    ✓ Peer-reviewed Disease mechanisms Nutrients

    Key finding: In addition, it has attracted attention as a target for the prevention and treatment of these chronic diseases. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2019-09-23

    Age-related hearing loss and tinnitus, dementia risk, and auditory amplification outcomes

    ✓ Peer-reviewed Prevention and risk Ageing research reviews

    Key finding: Age-related hearing loss (ARHL) or presbycusis, as the third leading cause of chronic disability in older adults, has been shown to be associated with predisposing cognitive impairment and dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2019-09-23

    Blood Pressure Variability and Progression of Clinical Alzheimer Disease

    ✓ Peer-reviewed Treatments Hypertension (Dallas, Tex. : 1979)

    Key finding: After 1 year, patients in the highest quartile of BPV had deteriorated more on Alzheimer's Disease Assessment Scale-cognitive subscale compared with patients in the lowest quartile (systolic: β, 2.24 [95% CI, 0.11-4.38], P =0.040; diastolic: β, 2.54 [95% CI, 0.33-4.75] P =0.024). +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2019-09-21

    Understanding neurodegeneration after traumatic brain injury: from mechanisms to clinical trials in dementia

    ✓ Peer-reviewed Getting a diagnosis Journal of neurology, neurosurgery, and psychiatry

    Key finding: These biomarkers could characterise endophenotypes associated with distinct types of post-traumatic neurodegeneration.

    Full summary, score breakdown and related studies → Original source

  17. 2019-09-20

    VGF Peptides in Cerebrospinal Fluid of Patients with Dementia with Lewy Bodies

    ✓ Peer-reviewed Tau biomarkers International journal of molecular sciences

    Key finding: VGF levels were lower in CSF from patients with DLB compared to either AD patients or controls. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2019-09-20

    Machine learning for comprehensive forecasting of Alzheimer's Disease progression

    ✓ Peer-reviewed Mild cognitive impairment Scientific reports

    Key finding: Moreover, our unsupervised model predicts changes in total ADAS-Cog scores with the same accuracy as specifically trained supervised models, additionally capturing the correlation structure in the components of ADAS-Cog, and identifies sub-components associated with word recall as predictive of progression.

    Full summary, score breakdown and related studies → Original source

  19. 2019-09-19

    Exercise and metformin counteract altered mitochondrial function in the insulin-resistant brain

    ✓ Peer-reviewed Prevention and risk JCI insight

    Key finding: Insulin resistance associates with increased risk for cognitive decline and dementia; however, the underpinning mechanisms for this increased risk remain to be fully defined. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2019-09-17

    Physical Activity and Brain Health

    ✓ Peer-reviewed Prevention trials Genes

    Key finding: Many studies have shown that PA can reverse at least some of the unwanted effects of sedentary lifestyle, and can also contribute in delaying brain aging and degenerative pathologies such as Alzheimer's Disease, diabetes, and multiple sclerosis.

    Full summary, score breakdown and related studies → Original source

  21. 2019-09-17

    Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Nature communications

    Key finding: Studies of rodent models of Alzheimer's disease (AD) and of human tissues suggest that the retinal changes that occur in AD, including the accumulation of amyloid beta (Aβ), may serve as surrogate markers of brain Aβ levels. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2019-09-17

    Early-life adversity and neurological disease: age-old questions and novel answers

    ✓ Peer-reviewed Caregiving Nature reviews. Neurology

    Key finding: These discoveries suggest that early-life adversity, especially in the perinatal period, influences the maturation of brain circuits involved in cognition. +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2019-09-16

    Wearable technological platform for multidomain diagnostic and exercise interventions in Parkinson's disease

    ✓ Peer-reviewed Prevention trials International review of neurobiology

    Key finding: For example, wearable device-enabled 6-min walking test can be automated to eliminate human supervision and many other technical factors that confound the results with conventional testing. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2019-09-16

    Risk of rhabdomyolysis with donepezil compared with rivastigmine or galantamine: a population-based cohort study

    ✓ Peer-reviewed Treatments CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    Key finding: The average age in our 2 groups was 81.1 years, and 61.4% of our population was female. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2019-09-16

    Cerebrospinal fluid biomarkers and cognitive status in differential diagnosis of frontotemporal dementia and Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers The Journal of international medical research

    Key finding: CSF Aß42 levels were lower, whereas t-tau/Aß42 and p-tau/Aß42 ratios were higher in patients with AD compared with those with FTD. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →