Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 24,951–24,975 of 27,380 studies, newest first · page 999 of 1096.
January 2002 25
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2002-01-01
Alzheimer's disease and related dementias increase costs of comorbidities in managed Medicare
53/100 ✓ Peer-reviewed Costs and economics Neurology
Key finding: In this study, prevalence rates for ADRD mirrored population estimates. +3 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
Folate, vitamin B12 and vitamin B6 and one carbon metabolism
36/100 ✓ Peer-reviewed Disparities The journal of nutrition, health & aging
Key finding: These associations could be due to a neurotoxic effect of homocysteine or to decreased availability of SAM which results in hypomethylation in the brain tissue.
Full summary, score breakdown and related studies → Original source
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2002-01-01
Estrogen actions throughout the brain
36/100 ✓ Peer-reviewed Disease mechanisms Recent progress in hormone research
Key finding: A new, rapid method of radioimmunocytochemistry has made possible the demonstration of synapse formation by labeling and quantifying the specific synaptic and dendritic molecules involved. +4 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus
36/100 ✓ Peer-reviewed Risk factors Brain research
Key finding: Recently it has been demonstrated that non-fibrillar assemblies of A beta possess electrophysiologic activity, with the corollary that they may produce dementia by disrupting neuronal signaling prior to cell death. +2 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
Advances in the treatment of Alzheimer's disease: benefits of dual cholinesterase inhibition
36/100 ✓ Peer-reviewed Treatments European neurology
Key finding: Rivastigmine is a dual inhibitor that has demonstrated benefits across the spectrum of AD severity and across the cognitive, functional and behavioural domains of AD.
Full summary, score breakdown and related studies → Original source
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2002-01-01
Clinical pharmacokinetics and pharmacodynamics of cholinesterase inhibitors
36/100 ✓ Peer-reviewed Treatments Clinical pharmacokinetics
Key finding: A conceptual model for cholinesterase inhibitors has been proposed, linking enzyme inhibition, clinical efficacy and adverse effects. +4 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
Butyrylcholinesterase: an important new target in Alzheimer's disease therapy
36/100 ✓ Peer-reviewed Treatments International psychogeriatrics
Key finding: Recent evidence suggests that both AChE and BuChE may have roles in the aetiology and progression of AD beyond regulation of synaptic ACh levels.
Full summary, score breakdown and related studies → Original source
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2002-01-01
High occurrence rate of glaucoma among patients with Alzheimer's disease
48/100 ✓ Peer-reviewed Brain scans and imaging European neurology
Key finding: When compared to a control group (5.2%) and to the prevalence of glaucoma in western countries revealed in a number of glaucoma surveys (2.6-4.7%), patients with AD may have a significantly increased occurrence rate of glaucoma.
Full summary, score breakdown and related studies → Original source
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2002-01-01
Insomnia in ischemic stroke patients
48/100 ✓ Peer-reviewed Vascular contributions Cerebrovascular diseases (Basel, Switzerland)
Key finding: Of 277 patients, 56.7% reported any insomnia complaint and 37.5% fulfilled the DSM-IV criteria of insomnia. +4 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
Effects of chronic epilepsy on intellectual functions
50/100 ✓ Peer-reviewed Hippocampus size on brain scans Progress in brain research
Key finding: We present results from two independent cross-sectional studies dealing with measures of global cognitive performance in two different ways. +2 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume
40/100 ✓ Peer-reviewed Hippocampus size on brain scans Molecular psychiatry
Key finding: Stress significantly decreased in vivo concentrations of N-acetyl-aspartate (-14%), creatine and phosphocreatine (-15%) and choline-containing compounds (-15%). +1 more finding
Full summary, score breakdown and related studies → Original source
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2002-01-01
The neurodevelopmental impact of childhood onset temporal lobe epilepsy on brain structure and function and the risk of progressive cognitive effects
50/100 ✓ Peer-reviewed Hippocampus size on brain scans Progress in brain research
Key finding: The purpose of this study is to explore the possibility of progressive neuropsychological decline in chronic temporal lobe epilepsy (TLE) and determine how this vulnerability may be associated with the neurodevelopmental impact of the disorder. 53 patients with TLE and 62 healthy controls underwent quantitative MRI volumetric imaging of total brain tissue and hippocampal volumes as well as assessment of intelligence and memory function. +4 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
Hippocampal pathology in refractory temporal lobe epilepsy: T2-weighted signal change reflects dentate gliosis
47/100 ✓ Peer-reviewed Hippocampus size on brain scans Neurology
Key finding: The results confirmed the correlation between hippocampal volumes and neuron cell counts. +1 more finding
Full summary, score breakdown and related studies → Original source
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2002 no date recorded — placed by publication year
Individual differences in rates of change in cognitive abilities of older persons.
47/100 ✓ Peer-reviewed How common it is Psychology and Aging
The authors examined change in cognitive abilities in older Catholic clergy members.
Full summary, score breakdown and related studies → Original source
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2002 no date recorded — placed by publication year
Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain
57/100 ✓ Peer-reviewed Brain scans and imaging NeuroImage
Key finding: Using this parcellation method, three procedures to perform the automated anatomical labeling of functional studies are proposed: (1) labeling of an extremum defined by a set of coordinates, (2) percentage of voxels belonging to each of the AVOI intersected by a sphere centered by a set of coordinates, and (3) percentage of voxels belonging to each of the AVOI intersected by an activated cluster. +3 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
Plasma levels of Abeta42 and Abeta40 in Alzheimer patients during treatment with the acetylcholinesterase inhibitor tacrine
37/100 ✓ Peer-reviewed Risk genes beyond APOE Dementia and geriatric cognitive disorders
Key finding: It has been suggested that stimulation of the muscarinic M(1) receptor subtype affects APP processing and leads to a change in Abeta concentration. +3 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
Whole Brain Segmentation
62/100 ✓ Peer-reviewed Brain scans and imaging Neuron
Key finding: The current method assigns one of 37 labels to each voxel, including left and right caudate, putamen, pallidum, thalamus, lateral ventricles, hippocampus, and amygdala. +2 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
Grocery Store Pricing and Its Effect on Initial and Ongoing Store Choice
23/100 ✓ Peer-reviewed Risk factors Marketing Management Journal
Key finding: Through a literature review and empirical research, the author confirms the results of over forty years of research into consumer price knowledge but questions internal reference price (IRP) theory. +1 more finding
Full summary, score breakdown and related studies → Original source
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2002-01-01
Dependence, Dementia, Cerebellar Dysfunction, and Myopathy in Association With Chronic Isopropanol Ingestion
24/100 ✓ Peer-reviewed Clinical safety Psychopharmacology Bulletin
Key finding: Little is known about the chronic sequelae of isopropanol ingestion. +4 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
Lithium Salts in AIDS and AIDS-Related Dementia
27/100 ✓ Peer-reviewed Long-term cohort studies Psychopharmacology Bulletin
Key finding: Studies have revealed, however, that the lithium ion also has significant granulopoietic actions, as well as regulatory effects on select cytokines that enable it to boost the body's natural defense against viral infections, specifically DNA viruses. +1 more finding
Full summary, score breakdown and related studies → Original source
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2002-01-01
Parkinson disease neuropathology: later-developing dementia and loss of the levodopa response
53/100 ✓ Peer-reviewed Brain tissue and pathology Archives of neurology
Key finding: We identified 13 patients with a clinical diagnosis of PD who experienced dementia at least 4 years after parkinsonism onset (mean, 10.5 years) and subsequently underwent postmortem examination. +3 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
Repetitive mild brain trauma accelerates Abeta deposition, lipid peroxidation, and cognitive impairment in a transgenic mouse model of Alzheimer amyloidosis
49/100 ✓ Peer-reviewed Brain tissue and pathology The Journal of neuroscience : the official journal of the Society for Neuroscience
Key finding: To address this question, we studied neuropathological and behavioral consequences of single versus repetitive mild TBI (mTBI) in transgenic (Tg) mice (Tg2576) that express mutant human Abeta precursor protein, and we demonstrate elevated brain Abeta levels and increased Abeta deposition. +3 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
The psychosocial burden on spouses of the elderly with stroke, dementia and Parkinson's disease
40/100 ✓ Peer-reviewed Cognitive tests and assessment International journal of geriatric psychiatry
Key finding: The psychosocial burden was recorded by the 15-item Relatives' Stress Scale (RSS). +3 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia
48/100 ✓ Peer-reviewed Mild cognitive impairment Journal of psychiatric research
Key finding: Plasma and CSF concentrations of 24S-hydroxycholesterol and cholesterol in 32 patients with Alzheimer's disease (AD), 11 patients with vascular dementia, seven patients with MCI, and seven cognitively intact control subjects were measured by combined gas-chromatography/mass spectrometry. +4 more findings
Full summary, score breakdown and related studies → Original source
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2002-01-01
Alcohol consumption and risk of dementia: the Rotterdam Study
61/100 ✓ Peer-reviewed Lewy body dementia Lancet (London, England)
Key finding: The average follow-up was 6.0 years. +3 more findings
Full summary, score breakdown and related studies → Original source
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