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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,451–18,475 of 27,380 studies, newest first · page 739 of 1096.

August 2013 25

  1. 2013-08-31

    Intracerebroventricular streptozotocin exacerbates Alzheimer-like changes of 3xTg-AD mice

    ✓ Peer-reviewed Risk genes beyond APOE Molecular neurobiology

    Key finding: To investigate the role of metabolic insults in AD, we injected streptozotocin (STZ), a diabetogenic compound if used in the periphery, into the lateral ventricle of the 6-month-old 3xTg-AD mice and studied the cognitive function as well as AD-like brain abnormalities, such as tau phosphorylation and Aβ accumulation, 3-6 weeks later. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2013-08-30

    Neuropsychological assessment and cerebral vascular disease: the new standards

    ✓ Peer-reviewed Biomarkers Revue neurologique

    Key finding: The adaption of the battery for French-speaking subjects is reported as well as preliminary results of the on-going validation study of the GRECOG-VASC group [Clinical Trial NCT01339195]. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2013-08-29

    Cognitive Stimulation in Patients with Dementia: Randomized Controlled Trial

    ✓ Peer-reviewed Risk factors Dementia and Geriatric Cognitive Disorders Extra

    Key finding: A new Geriatric Depression Scale (GDS) designed specifically for rating depression in the elderly was tested for reliability and validity and compared with the Hamilton Rating Scale for Depression (HRS-D) and the Zung Self-Rating Depression Scale (SDS). +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2013-08-29

    Cognitive reserve in Parkinson's disease: a systematic review and meta-analysis

    ✓ Peer-reviewed Cognitive tests and assessment Parkinsonism & related disorders

    Key finding: The concept of cognitive reserve is proposed to explain the mismatch between the degree of pathological changes and their clinical manifestations and has been used to help understand the variation in the rate of cognitive decline and the development of dementias. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2013-08-28

    Antisaccade task reflects cortical involvement in mild cognitive impairment

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: The AS task is a useful measure of executive function across the AD spectrum.

    Full summary, score breakdown and related studies → Original source

  6. 2013-08-26

    Inflammation in Alzheimer’s disease: insights from immunotherapy

    ✓ Peer-reviewed Treatments Brain

    Key finding: Genome-wide association studies have identified a number of risk variants for Alzheimer’s disease implicated in inflammatory responses (Bettens et al., 2013); exome sequencing has revealed polymorphisms in the microglial receptor TREM2 gene as a rare but significant risk for Alzheimer’s disease (Guerreiro et al., 2013; Jonsson et al., 2013); and recently, the CD33 risk allele has been shown to inhibit microglial clearance of amyloid-β (Bradshaw et al., 2013; Griciuc et al., 2013). +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2013-08-24

    Metabolic features of the cell danger response

    ✓ Peer-reviewed Disease mechanisms Mitochondrion

    Key finding: When the CDR persists abnormally, whole body metabolism and the gut microbiome are disturbed, the collective performance of multiple organ systems is impaired, behavior is changed, and chronic disease results.

    Full summary, score breakdown and related studies → Original source

  8. 2013-08-22

    The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-ε4 carriers

    ✓ Peer-reviewed Biomarkers PLoS genetics

    Key finding: Surprisingly, a coding variant in PSEN1, p.E318G (rs17125721-G) exhibited a significant association with high CSF tau (p = 9.2 × 10(-4)) and ptau (p = 1.8 × 10(-3)) levels. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2013-08-22

    Dysfunctional synapse in Alzheimer's disease - A focus on NMDA receptors

    ✓ Peer-reviewed Disease mechanisms Neuropharmacology

    Key finding: Moreover, N-methyl-D-aspartate (NMDA) receptors (NMDARs) activation has been recently implicated in AD-related synaptic dysfunction. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2013-08-21

    Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer's disease

    ✓ Peer-reviewed Drug development Neuropharmacology

    Key finding: It has been shown that insulin signalling is desensitised in the brains of AD patients. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2013-08-21

    Enhanced taupathy and AD-like pathology in aged primate brains decades after infantile exposure to lead (Pb)

    ✓ Peer-reviewed Risk genes beyond APOE Neurotoxicology

    Key finding: Amyloidosis and tau pathology, which are present in AD brains, appear to be sporadic in nature. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2013-08-21

    Amyloid imaging: the court of public opinion

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Human amyloid imaging is one of the great recent translational medicine stories. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2013-08-20

    A comparison of early diagnostic utility of Alzheimer disease biomarkers in brain magnetic resonance and cerebrospinal fluid

    ✓ Peer-reviewed Tau biomarkers Neurologia (Barcelona, Spain)

    Key finding: The goals of this study were to compare the early diagnostic utility of Alzheimer disease biomarkers in the CSF with those in brain MRI in conditions found in our clinical practice, and to ascertain the diagnostic accuracy of both techniques used together. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2013-08-20

    A physical interaction between the adaptor proteins DOK3 and DAP12 is required to inhibit lipopolysaccharide signaling in macrophages

    ✓ Peer-reviewed TREM2 and immune genetics Science signaling

    Key finding: DAP12 inhibits Toll-like receptor (TLR) signaling, such as that of TLR4 in response to its ligand lipopolysaccharide (LPS), as well as cytokine responses by coupling to TREM2 (triggering receptor expressed on myeloid cells 2) at the plasma membrane. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2013-08-20

    Prevalences of dementia and cognitive impairment among older people in sub-Saharan Africa: a systematic review

    ✓ Peer-reviewed Disparities Bulletin of the World Health Organization

    Key finding: A total of 2320 unique papers was found; the full text of 87 was reviewed.

    Full summary, score breakdown and related studies → Original source

  16. 2013-08-20

    A systematic review of Internet-based supportive interventions for caregivers of patients with dementia

    ✓ Peer-reviewed Caregiving International journal of geriatric psychiatry

    Key finding: Internet interventions for informal dementia caregivers may improve caregiver well-being. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2013-08-19

    Delirium superimposed on dementia is associated with prolonged length of stay and poor outcomes in hospitalized older adults

    ✓ Peer-reviewed Clinical safety Journal of hospital medicine

    Key finding: Delirium prolongs hospitalization for persons with dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2013-08-19

    Predictors of survival in a series of clinically diagnosed progressive supranuclear palsy patients

    ✓ Peer-reviewed Digital health tools Parkinsonism & related disorders

    Key finding: Forty-three consecutive patients were enrolled (86% Richardson's syndrome). +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2013-08-19

    Pain, depression, and fatigue: loneliness as a longitudinal risk factor

    ✓ Peer-reviewed Caregiving Health psychology : official journal of the Division of Health Psychology, American Psychological Association

    Key finding: Two longitudinal studies with different populations demonstrated that loneliness was a risk factor for the development of the pain, depression, and fatigue symptom cluster over time. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2013-08-17

    Association between frailty and dementia: a population-based study

    ✓ Peer-reviewed Cognitive tests and assessment Gerontology

    Key finding: Frailty is commonly considered as a syndrome with several symptoms, including weight loss, exhaustion, weakness, slow walking speed and physical inactivity. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2013-08-15

    Hyperphosphorylation-induced tau oligomers

    ✓ Peer-reviewed Down syndrome and Alzheimer's Frontiers in neurology

    Key finding: The abnormally hyperphosphorylated tau is capable of sequestering not only normal tau but also MAP MAP1 and MAP2 and causing disruption of the microtubule network promoted by these proteins. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2013-08-15

    Validation of the Addenbrooke's Cognitive Examination III in frontotemporal dementia and Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis Dementia and geriatric cognitive disorders

    Key finding: The results of this study provide objective validation of the ACE-III as a screening tool for cognitive deficits in FTD and AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2013-08-14

    Hippocampal subfield volumetry in mild cognitive impairment, Alzheimer's disease and semantic dementia

    ✓ Peer-reviewed Brain scans and imaging NeuroImage. Clinical

    Key finding: The findings suggest that CA1 measurement is more sensitive than global hippocampal volumetry to detect structural changes at the pre-dementia stage, although the predominance of CA1 atrophy does not appear to be specific to AD pathophysiological processes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2013-08-14

    A change in sleep pattern may predict Alzheimer disease

    ✓ Peer-reviewed Prevention and risk The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Self-reported sleep problems may increase the risk for dementia, and depressive symptoms may explain this relationship. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2013-08-14

    PET approaches for diagnosis of dementia

    ✓ Peer-reviewed Biomarkers AJNR. American journal of neuroradiology

    Key finding: For example, FDG-PET demonstrates hypometabolic regions in the posterior cingulate gyri, precuneus, and parietotemporal association cortices, while amyloid PET indicates amyloid deposition in Alzheimer disease and mild cognitive impairment due to Alzheimer disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →