Newest studies

LOWER COMMUNITY LIVABILITY IS ASSOCIATED WITH HIGHER DEMENTIA PREVALENCE AMONG WOMEN IN SOUTH CAROLINA COUNTIES

36/100 ✓ Peer-reviewed Risk factors Innovation in Aging

Key finding: In adjusted analyses, low vs. high livability was associated with higher dementia prevalence (B=0.38; p-value=0.31). +4 more findings

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Implementing a Dementia‐Friendly Communities programme across local authorities in the East of England

28/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: There are many types of Dementia‐Friendly Communities (DFCs), and communities define and implement them in different ways. +4 more findings

• Policy

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Alzheimer’s Disease and related dementias prevalence higher in Appalachian counties within Central Appalachia

38/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: There is a consistent difference between Appalachian and non‐Appalachian counties, with Appalachian counties having relatively higher ADRD prevalence (in the range of 2.0‐3.0% times higher) than non‐Appalachian counties. +3 more findings

• Risk Factors
• Policy

Full summary, score breakdown and related studies → Original source

The Psychosocial Analyzation of Alzheimer’s Disease and other Dementia among Black Ohioans

30/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: Black Ohioans are concerned about the rising prevalence of Alzheimer’s Disease, however social barriers that prevent equitable access to care, support and treatment is of overwhelming concern.

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ACCESS TO HIGH-QUALITY HOME HEALTH CARE FOR PERSONS WITH DEMENTIA

31/100 ✓ Peer-reviewed Risk factors Innovation in Aging

Key finding: Using multiple Medicare Public Use Files (PUF), including star ratings for home health quality of patient care (QoPC), home health care CAHPS survey (HHCAHPS), county-level ADRD prevalence, and Medicare FFS enrollment, we found that the median county-level number of home health agencies was 15 (IQR 8-29), star rating was 3.4 (IQR 3.1-3.7) for QoPC and 3.8 (IQR 3.5-4.0) for HHCAHPS. +1 more finding

• Care Services

Full summary, score breakdown and related studies → Original source

Evaluating Sociodemographic Bias in an Artificial Intelligence Algorithm to Detect Cognitive Impairment in Electronic Health Records

34/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: Our study highlights the potential of Decipher‐AI for screening undiagnosed cognitive impairment in primary care. +2 more findings

• Diagnosis
• Digital Tools
• Health Equity

Full summary, score breakdown and related studies → Original source

Neighborhood Deprivation, Subjective and Objective Cognitive Impairment

38/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: Neighborhood deprivation is associated with Future research should investigate the possible mechanisms of this association to identify optimal interventions at the neighborhood level. +4 more findings

• Diagnosis
• Health Equity

Full summary, score breakdown and related studies → Original source

County‐level indicators of education quality and brain imaging markers of neurodegeneration and vascular injury among racially and ethnically diverse middle‐aged and older adults

41/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: Higher teacher‐student ratio was associated with greater gray matter volume (β = 6.25, 95% CI: 1.57, 10.92) but was not associated hippocampal volume (β = ‐0.01, 95% CI: ‐0.14, 0.11), ventricular volume (β = ‐0.04, 95% CI: ‐0.13, 0.04), or white matter hyperintensity (β = ‐0.02, 95% CI: ‐0.31, 0.26) (Table 2). +4 more findings

• Brain Scans

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Impact of race/ethnicity and area deprivation index on Alzheimer’s disease and related disorders biomarkers in the POINTER Cohort

38/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: The analyses of the community‐based U.S. POINTER indicate that AA/B individuals present differences in AD and related dementia biomarker values. nHW had higher fully adjusted cognitive scores. +4 more findings

• Health Equity
• Biomarkers
• Brain Scans

Full summary, score breakdown and related studies → Original source

Residential Neighborhood Disadvantage and Amyloid Positivity: Findings from IDEAS

37/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: We observed a relationship between residence in a more disadvantaged neighborhood (higher ADI) and lower rates of amyloid positivity. +4 more findings

• Health Equity

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Residential Neighborhood Disadvantage and Amyloid Positivity: Findings from IDEAS

37/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: We observed a relationship between residence in a more disadvantaged neighborhood (higher ADI) and lower rates of amyloid positivity. +4 more findings

• Health Equity

Full summary, score breakdown and related studies → Original source

Expo‐AD: An Innovative Alzheimer’s Disease and Related Dementias (ADRD) Research Infrastructure for Secure Data Integration and Exposome Linkage

33/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: Access is controlled through both technical and procedural methods and overseen by an external advisory committee Results Expo‐AD is currently storing personal identifiers and neuropathology data of 10,875 brain donors acquired from 22 participating brain banks and the National Alzheimer’s Coordinating Center.

Full summary, score breakdown and related studies → Original source

Factors influencing adults' willingness to be screened for dementia risk

34/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: Although White and non-White participants were both willing to test (∼77%), non-White participants were approximately four times more likely to test only if their results were not shared with their medical provider/insurer. +4 more findings

• Risk Factors
• Health Equity

Full summary, score breakdown and related studies → Original source

Evaluating Sociodemographic Bias in an Artificial Intelligence Algorithm to Detect Cognitive Impairment in Electronic Health Records

38/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: Our study highlights the potential of Decipher‐AI for screening undiagnosed cognitive impairment in primary care. +2 more findings

• Diagnosis
• Digital Tools
• Health Equity

Full summary, score breakdown and related studies → Original source

Associations of Neighborhood Walkability with Cognitive Impairment Depend on Geographic Context

41/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: In adjusted analyses, walkability was not related to cognitive impairment in the full sample (OR = 0.89 (95% CI: 0.61‐1.28 for highest vs lowest quartile). +1 more finding

Full summary, score breakdown and related studies → Original source

Modeling Early Detection and Geographic Variation in Health System Capacity for Alzheimer’s Disease‐Modifying Therapies

36/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: Widespread delivery of AD‐modifying therapies will require a combination of strategies to communicate the value of detection and treatment to patients, integrate PCPs into the detection and diagnosis pathway, and address capacity disparities across the United States. +2 more findings

• Treatments
• Diagnosis
• Care Services

Full summary, score breakdown and related studies → Original source

POLICY SERIES: INEQUITABLE IMPACTS OF POLICY AND PAYMENT CHANGES ON CARE USE AND OUTCOMES FOR OLDER ADULTS WITH HIGH CARE NEEDS

27/100 ✓ Peer-reviewed Health systems and care delivery Innovation in Aging

Key finding: Over the past decade, the CMS has introduced numerous value-based policy initiatives. +1 more finding

• Health Equity
• Policy
• Care Services

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HEALTH SYSTEM ADOPTION OF COMMUNITY-BASED EXERCISE FOR OLDER ADULTS TO ADDRESS LONELINESS AND SOCIAL ISOLATION

34/100 ✓ Peer-reviewed Health systems and care delivery Innovation in Aging

Key finding: Research participants enrolled in Falls Prevention EBPs reported decreased levels of loneliness and social isolation and were referred by physicians, social workers, and pharmacists using an order in the electronic medical record (EMR). +1 more finding

• Lifestyle
• Care Services

Full summary, score breakdown and related studies → Original source

Screening for the Spectrum of Cognitive Impairment in Primary Care: Development of a Machine Learning Informed, Workflow‐Friendly Care Model

39/100 ✓ Peer-reviewed Health systems and care delivery Alzheimer s & Dementia

Key finding: In the testing cohort, the super learner obtained a concordance statistic (95% confidence interval) of 0.822 (0.810, 0.835), higher than any of the individual ML models (Figure 1), and its predicted risk aligned with observed risk in calibration slope plots (Figure 2). +1 more finding

• Care Services
• Diagnosis

Full summary, score breakdown and related studies → Original source

FUNCTIONAL OUTCOME IN HOME HEALTH AMONG TRADITIONAL MEDICARE AND MEDICARE ADVANTAGE BENEFICIARIES WITH DEMENTIA

44/100 ✓ Peer-reviewed Health systems and care delivery Innovation in Aging

Key finding: This study examines the difference in functional outcomes among Traditional Medicare (TM) and Medicare Advantage (MA) beneficiaries with Alzheimer’s disease and related dementias (ADRD) during a home health admission, which is unknown. +4 more findings

• Care Services
• Policy

Full summary, score breakdown and related studies → Original source

Differences in Dementia Diagnosis Rates in Primary Care in Traditional Medicare and Medicare Advantage

33/100 ✓ Peer-reviewed Health systems and care delivery Alzheimer s & Dementia

Key finding: We find that even for a matched sample of TM and MA patients with the same PCP, dementiadiagnosis rates are lower in MA relative to TM. +2 more findings

• Care Services
• Diagnosis
• Policy

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Changes to Medicare Advantage Risk Adjustment and Dementia Diagnosis in Older Adults

33/100 ✓ Peer-reviewed Health systems and care delivery Alzheimer s & Dementia

Key finding: Financial incentives to detect dementia resulted in more dementia diagnoses, particularly among persons at high risk of dementia and of undetected dementia but also raises concerns about diagnostic upcoding and the potential for over‐diagnosis. +2 more findings

• Diagnosis
• Policy

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Our youth, our compass: families walking with younger‐onset dementia shine light on stigma

29/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: We are building our alliance of empowered young ambassadors, and expect more than 200 youth at Lorenzo’s Youth Summit 2024. +4 more findings

• Lifestyle
• Caregiving

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Alzheimer Disease as a Clinical-Biological Construct-An International Working Group Recommendation

61/100 ✓ Peer-reviewed Getting a diagnosis JAMA neurology

Key finding: In the new AA diagnostic criteria, AD can be defined clinically as encompassing cognitively normal people having a core 1 AD biomarker. +4 more findings

• Diagnosis
• Biomarkers

Full summary, score breakdown and related studies → Original source

High-Risk Medications in Persons Living With Dementia: A Randomized Clinical Trial

71/100 ✓ Peer-reviewed Treatments JAMA internal medicine

Key finding: These findings suggest medication-specific educational mailings targeting patients with AD or ADRD and their clinicians are not effective in reducing the use of high-risk medications. +3 more findings

• Clinical Trials
• Treatments

Full summary, score breakdown and related studies → Original source