Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,701–19,725 of 27,380 studies, newest first · page 789 of 1096.

January 2012 25

  1. 2012-01-02

    Essential tremor: beyond the motor features

    ✓ Peer-reviewed Risk factors Parkinsonism & related disorders

    Key finding: There is a growing evidence to suggest that apart from motor features, patients with Essential Tremor (ET) may have significant non-motor features.

  2. 2012-01-01

    Neuroprotective potential of phytochemicals

    ✓ Peer-reviewed Risk factors Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review

    Key finding: In this review paper, we attempt to throw some light on the use of medicinal herbs to treat cognitive disorders. +4 more findings

  3. 2012-01-01

    Oxidative stress and human health

    ✓ Peer-reviewed Brain scans and imaging Advances in Bioscience and Biotechnology

    Key finding: Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species (ROS), such as hydrogen peroxide, organic hydro peroxides, nitric oxide, superoxide and hydroxyl radicals etc. +1 more finding

  4. 2012-01 month only

    Autophagy in dementias

    ✓ Peer-reviewed Disease mechanisms Brain pathology (Zurich, Switzerland)

    Key finding: Dementias are a varied group of disorders typically associated with memory loss, impaired judgment and/or language and by symptoms affecting other cognitive and social abilities to a degree that interferes with daily functioning. +1 more finding

  5. 2012-01-01

    Neurological phenotypes for Down syndrome across the life span

    ✓ Peer-reviewed Digital health tools Progress in brain research

    Key finding: As the result of these morphological abnormalities, brain circuitry is impaired. +1 more finding

  6. 2012-01-01

    Guidelines for management of idiopathic normal pressure hydrocephalus: second edition

    ✓ Peer-reviewed Digital health tools Neurologia medico-chirurgica

    Key finding: Clinical and basic research on iNPH has increased significantly, and more high-level evidence has since been generated.

  7. 2012-01-01

    Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature

    ✓ Peer-reviewed Brain tissue and pathology Cold Spring Harbor perspectives in medicine

    Key finding: Biochemical and neuropathological studies of brains from individuals with Alzheimer disease (AD) provide clear evidence for an activation of inflammatory pathways, and long-term use of anti-inflammatory drugs is linked with reduced risk to develop the disease. +2 more findings

  8. 2012-01-01

    Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: The effect of apolipoprotein E (APOE) genotype on the presence of protein aggregates associated with Alzheimer's disease (AD) pathology was also explored. +2 more findings

  9. 2012-01-01

    Neuronal uptake and neuroprotective effect of curcumin-loaded PLGA nanoparticles on the human SK-N-SH cell line

    ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD

    Key finding: In vitro release kinetics of curcumin from Nps-Cur revealed a biphasic pattern with an initial exponential phase followed by a slow release phase. +2 more findings

  10. 2012-01-01

    Gantenerumab: a novel human anti-Aβ antibody demonstrates sustained cerebral amyloid-β binding and elicits cell-mediated removal of human amyloid-β

    ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD

    Key finding: The amyloid-β lowering capacity of anti-Aβ antibodies has been demonstrated in transgenic models of Alzheimer's disease (AD) and in AD patients. +3 more findings

  11. 2012-01-01

    Intraindividual cognitive decline using a brief computerized cognitive screening test

    ✓ Peer-reviewed Cognitive tests and assessment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Intraindividual decline in cognitive performance can be detected in otherwise healthy, community-dwelling, older persons, and this may deserve further study as a potential indicator of early Alzheimer's disease pathology.

  12. 2012-01-01

    Plasma transthyretin as a candidate marker for Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Among these, one of the most interesting candidates is transthyretin (TTR), the carrier of thyroxine and retinol, which also binds with amyloid-β (Aβ), and it has been suggested that it protects against Aβ deposition. +3 more findings

  13. 2012-01-01

    Risk of Alzheimer's disease biological misdiagnosis linked to cerebrospinal collection tubes

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Significant concentration variations linked solely to the use of different types of tubes were observed. +2 more findings

  14. 2012-01-01

    Dementia, stroke, and vascular risk factors; a review

    ✓ Peer-reviewed Vascular contributions International journal of stroke : official journal of the International Stroke Society

    Key finding: The relationship between Alzheimer's disease and vascular cognitive impairment is unclear, although there exists significant overlap, which prompts physicians to consider them opposite ends of a disease spectrum, rather than separate entities. +2 more findings

  15. 2012-01-01

    Health risk factors in caregivers of terminal cancer patients: a pilot study

    ✓ Peer-reviewed End-of-life care Cancer nursing

    Key finding: The caregiving stressor is associated with considerable psychological vulnerability, sleep disorders, and risk of alterations in the cardiovascular system, which seem to be modulated by caregiving characteristics. +4 more findings

  16. 2012-01-01

    Toward the realization of a better aged society: messages from gerontology and geriatrics

    ✓ Peer-reviewed Clinical safety Geriatrics & gerontology international

    Key finding: Compared with France, where the percentage of the elderly population has increased just twofold in the past 100 years, Japanese society is aging at an unprecedented rate. +2 more findings

  17. 2012-01-01

    Polyphenol-rich foods in the Mediterranean diet are associated with better cognitive function in elderly subjects at high cardiovascular risk

    ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD

    Key finding: Urinary polyphenols were associated with better scores in immediate verbal memory [1.208 (0.236-2.180)]. +2 more findings

  18. 2012-01-01

    Nonhuman primate models of Alzheimer-like cerebral proteopathy

    ✓ Peer-reviewed Disease mechanisms Current pharmaceutical design

    Key finding: In contrast, significant tauopathy is unusual in simians, and only humans manifest the profound tauopathy, neuronal degeneration and cognitive impairment that characterize Alzheimer's disease. +1 more finding

  19. 2012-01-01

    Exercise, Physical Activity and Breast Cancer: The Role of Tumor-Associated Macrophages

    ✓ Peer-reviewed Prevention and risk Exercise immunology review

    Key finding: Termed tumor-associated macrophages (TAMs), these immune cells are highly plastic and respond to different signals from the cancer microenvironment, causing them to either display tumor-promoting or tumor-suppressing phenotypes. +4 more findings

  20. 2012-01-01

    Maternal family history is associated with Alzheimer's disease biomarkers

    ✓ Peer-reviewed Long-term cohort studies Journal of Alzheimer's disease : JAD

    Key finding: Accumulating evidence suggests that a family history of dementia associates with AD-typical biomarker changes. +3 more findings

  21. 2012-01-01

    Weight loss and rapid cognitive decline in community-dwelling patients with Alzheimer's disease

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD

    Key finding: The aim of this study was to determine whether weight loss was a predictor of rapid cognitive decline (RCD) in AD. +3 more findings

  22. 2012-01-01

    Microglial activation and TDP-43 pathology correlate with executive dysfunction in amyotrophic lateral sclerosis

    ✓ Peer-reviewed Cognitive tests and assessment Acta neuropathologica

    Key finding: Staining for neurodegenerative disease pathology, TDP-43, and microglial activation markers (CD68, Iba1) was performed in 102 autopsy cases of ALS, and neuropathology data were related to clinical and neuropsychological measures. +3 more findings

  23. 2012-01-01

    Early onset Alzheimer's disease is associated with a distinct neuropsychological profile

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD

    Key finding: We examined neuropsychological performance according to age-at-onset. +3 more findings

  24. 2012-01-01

    The effectiveness and cost-effectiveness of donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer's disease (review of Technology Appraisal No. 111): a systematic review and economic model

    ⚠ Report — not peer-reviewed Cognitive tests and assessment Health technology assessment (Winchester, England)

    Key finding: Alzheimer’s disease (AD) is the most commonly occurring form of dementia. +3 more findings

    Scored 49 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

  25. 2012-01-01

    Cerebrospinal Fluid Alzheimer Markers in Depressed Elderly Subjects with and without Alzheimer's Disease

    ✓ Peer-reviewed Tau biomarkers Dementia and geriatric cognitive disorders extra

    Key finding: The aim of this study was to explore the relationship between cerebrospinal fluid Alzheimer's disease (AD) markers and depression in elderly people. +3 more findings

Browse the library by subject, with the full score breakdown →