Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 19,701–19,725 of 27,380 studies, newest first · page 789 of 1096.
January 2012 25
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2012-01-02
Essential tremor: beyond the motor features
36/100 ✓ Peer-reviewed Risk factors Parkinsonism & related disorders
Key finding: There is a growing evidence to suggest that apart from motor features, patients with Essential Tremor (ET) may have significant non-motor features.
Full summary, score breakdown and related studies → Original source
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2012-01-01
Neuroprotective potential of phytochemicals
40/100 ✓ Peer-reviewed Risk factors Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review
Key finding: In this review paper, we attempt to throw some light on the use of medicinal herbs to treat cognitive disorders. +4 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Oxidative stress and human health
38/100 ✓ Peer-reviewed Brain scans and imaging Advances in Bioscience and Biotechnology
Key finding: Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species (ROS), such as hydrogen peroxide, organic hydro peroxides, nitric oxide, superoxide and hydroxyl radicals etc. +1 more finding
Full summary, score breakdown and related studies → Original source
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2012-01 month only
Autophagy in dementias
38/100 ✓ Peer-reviewed Disease mechanisms Brain pathology (Zurich, Switzerland)
Key finding: Dementias are a varied group of disorders typically associated with memory loss, impaired judgment and/or language and by symptoms affecting other cognitive and social abilities to a degree that interferes with daily functioning. +1 more finding
Full summary, score breakdown and related studies → Original source
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2012-01-01
Neurological phenotypes for Down syndrome across the life span
36/100 ✓ Peer-reviewed Digital health tools Progress in brain research
Key finding: As the result of these morphological abnormalities, brain circuitry is impaired. +1 more finding
Full summary, score breakdown and related studies → Original source
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2012-01-01
Guidelines for management of idiopathic normal pressure hydrocephalus: second edition
36/100 ✓ Peer-reviewed Digital health tools Neurologia medico-chirurgica
Key finding: Clinical and basic research on iNPH has increased significantly, and more high-level evidence has since been generated.
Full summary, score breakdown and related studies → Original source
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2012-01-01
Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature
36/100 ✓ Peer-reviewed Brain tissue and pathology Cold Spring Harbor perspectives in medicine
Key finding: Biochemical and neuropathological studies of brains from individuals with Alzheimer disease (AD) provide clear evidence for an activation of inflammatory pathways, and long-term use of anti-inflammatory drugs is linked with reduced risk to develop the disease. +2 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults
36/100 ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD
Key finding: The effect of apolipoprotein E (APOE) genotype on the presence of protein aggregates associated with Alzheimer's disease (AD) pathology was also explored. +2 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Neuronal uptake and neuroprotective effect of curcumin-loaded PLGA nanoparticles on the human SK-N-SH cell line
36/100 ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD
Key finding: In vitro release kinetics of curcumin from Nps-Cur revealed a biphasic pattern with an initial exponential phase followed by a slow release phase. +2 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Gantenerumab: a novel human anti-Aβ antibody demonstrates sustained cerebral amyloid-β binding and elicits cell-mediated removal of human amyloid-β
36/100 ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD
Key finding: The amyloid-β lowering capacity of anti-Aβ antibodies has been demonstrated in transgenic models of Alzheimer's disease (AD) and in AD patients. +3 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Intraindividual cognitive decline using a brief computerized cognitive screening test
40/100 ✓ Peer-reviewed Cognitive tests and assessment Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: Intraindividual decline in cognitive performance can be detected in otherwise healthy, community-dwelling, older persons, and this may deserve further study as a potential indicator of early Alzheimer's disease pathology.
Full summary, score breakdown and related studies → Original source
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2012-01-01
Plasma transthyretin as a candidate marker for Alzheimer's disease
48/100 ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD
Key finding: Among these, one of the most interesting candidates is transthyretin (TTR), the carrier of thyroxine and retinol, which also binds with amyloid-β (Aβ), and it has been suggested that it protects against Aβ deposition. +3 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Risk of Alzheimer's disease biological misdiagnosis linked to cerebrospinal collection tubes
36/100 ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD
Key finding: Significant concentration variations linked solely to the use of different types of tubes were observed. +2 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Dementia, stroke, and vascular risk factors; a review
36/100 ✓ Peer-reviewed Vascular contributions International journal of stroke : official journal of the International Stroke Society
Key finding: The relationship between Alzheimer's disease and vascular cognitive impairment is unclear, although there exists significant overlap, which prompts physicians to consider them opposite ends of a disease spectrum, rather than separate entities. +2 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Health risk factors in caregivers of terminal cancer patients: a pilot study
36/100 ✓ Peer-reviewed End-of-life care Cancer nursing
Key finding: The caregiving stressor is associated with considerable psychological vulnerability, sleep disorders, and risk of alterations in the cardiovascular system, which seem to be modulated by caregiving characteristics. +4 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Toward the realization of a better aged society: messages from gerontology and geriatrics
40/100 ✓ Peer-reviewed Clinical safety Geriatrics & gerontology international
Key finding: Compared with France, where the percentage of the elderly population has increased just twofold in the past 100 years, Japanese society is aging at an unprecedented rate. +2 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Polyphenol-rich foods in the Mediterranean diet are associated with better cognitive function in elderly subjects at high cardiovascular risk
45/100 ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD
Key finding: Urinary polyphenols were associated with better scores in immediate verbal memory [1.208 (0.236-2.180)]. +2 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Nonhuman primate models of Alzheimer-like cerebral proteopathy
36/100 ✓ Peer-reviewed Disease mechanisms Current pharmaceutical design
Key finding: In contrast, significant tauopathy is unusual in simians, and only humans manifest the profound tauopathy, neuronal degeneration and cognitive impairment that characterize Alzheimer's disease. +1 more finding
Full summary, score breakdown and related studies → Original source
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2012-01-01
Exercise, Physical Activity and Breast Cancer: The Role of Tumor-Associated Macrophages
39/100 ✓ Peer-reviewed Prevention and risk Exercise immunology review
Key finding: Termed tumor-associated macrophages (TAMs), these immune cells are highly plastic and respond to different signals from the cancer microenvironment, causing them to either display tumor-promoting or tumor-suppressing phenotypes. +4 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Maternal family history is associated with Alzheimer's disease biomarkers
49/100 ✓ Peer-reviewed Long-term cohort studies Journal of Alzheimer's disease : JAD
Key finding: Accumulating evidence suggests that a family history of dementia associates with AD-typical biomarker changes. +3 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Weight loss and rapid cognitive decline in community-dwelling patients with Alzheimer's disease
48/100 ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD
Key finding: The aim of this study was to determine whether weight loss was a predictor of rapid cognitive decline (RCD) in AD. +3 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Microglial activation and TDP-43 pathology correlate with executive dysfunction in amyotrophic lateral sclerosis
48/100 ✓ Peer-reviewed Cognitive tests and assessment Acta neuropathologica
Key finding: Staining for neurodegenerative disease pathology, TDP-43, and microglial activation markers (CD68, Iba1) was performed in 102 autopsy cases of ALS, and neuropathology data were related to clinical and neuropsychological measures. +3 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
Early onset Alzheimer's disease is associated with a distinct neuropsychological profile
49/100 ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD
Key finding: We examined neuropsychological performance according to age-at-onset. +3 more findings
Full summary, score breakdown and related studies → Original source
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2012-01-01
The effectiveness and cost-effectiveness of donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer's disease (review of Technology Appraisal No. 111): a systematic review and economic model
16/100 ⚠ Report — not peer-reviewed Cognitive tests and assessment Health technology assessment (Winchester, England)
Key finding: Alzheimer’s disease (AD) is the most commonly occurring form of dementia. +3 more findings
Scored 49 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2012-01-01
Cerebrospinal Fluid Alzheimer Markers in Depressed Elderly Subjects with and without Alzheimer's Disease
48/100 ✓ Peer-reviewed Tau biomarkers Dementia and geriatric cognitive disorders extra
Key finding: The aim of this study was to explore the relationship between cerebrospinal fluid Alzheimer's disease (AD) markers and depression in elderly people. +3 more findings
Full summary, score breakdown and related studies → Original source
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