alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 17,401–17,425 of 27,380 studies, newest first · page 697 of 1096.

January 2015 17

  1. 2015-01-01

    Clinical correlations with Lewy body pathology in LRRK2-related Parkinson disease

    ✓ Peer-reviewed Lewy body dementia JAMA neurology

    Key finding: However, LB pathology in LRRK2-related PD may be a marker for a broader parkinsonian symptom complex including cognitive impairment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2015-01-01

    Tau imaging: early progress and future directions

    ✓ Peer-reviewed Lewy body dementia The Lancet. Neurology

    Key finding: Use of selective in-vivo tau imaging will enable improved understanding of tau aggregation in the brain, facilitating research into causes, diagnosis, and treatment of major tauopathies such as Alzheimer's disease, progressive supranuclear palsy, corticobasal syndrome, chronic traumatic encephalopathy, and some variants of frontotemporal lobar degeneration. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2015-01-01

    The neuropathology of traumatic brain injury

    ✓ Peer-reviewed Lewy body dementia Handbook of clinical neurology

    Key finding: Evidence indicates that a single traumatic brain injury can precipitate or accelerate multiple age-related neurodegenerations, increase the risk of developing Alzheimer's disease, Parkinson's disease, and motor neuron disease, and that repetitive mild traumatic brain injuries can provoke the development of a tauopathy, chronic traumatic encephalopathy. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2015-01-01

    Notch signaling and ageing

    ✓ Peer-reviewed Down syndrome and Alzheimer's Advances in experimental medicine and biology

    Key finding: Notch signaling is a master controller of the neural stem cell and neural development maintaining a significant role in the normal brain function.

    Full summary, score breakdown and related studies → Original source

  5. 2015-01-01

    Bach1 overexpression in Down syndrome correlates with the alteration of the HO-1/BVR-a system: insights for transition to Alzheimer's disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of Alzheimer's disease : JAD

    Key finding: To corroborate our findings, we analyzed Bach1, HO-1, and BVR-A status in the Ts65Dn mouse model at 3 (young) and 15 (old) months of age.

    Full summary, score breakdown and related studies → Original source

  6. 2015-01-01

    Risk factors and screening instruments to predict adverse outcomes for undifferentiated older emergency department patients: a systematic review and meta-analysis

    ✓ Peer-reviewed Risk factors Academic emergency medicine : official journal of the Society for Academic Emergency Medicine

    Key finding: Studies were significantly heterogeneous in terms of country, outcomes assessed, and the timing of post-ED outcome assessments. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2015-01-01

    Longitudinal EEG changes correlate with cognitive measure deterioration in Parkinson's disease

    ✓ Peer-reviewed Digital health tools Journal of Parkinson's disease

    Key finding: Changes in delta bandpower showed the highest and most consistent pattern of correlations with longitudinal changes in neuropsychological testing. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2015-01-01

    Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study

    ✓ Peer-reviewed Disparities Alzheimer disease and associated disorders

    Key finding: Few prior studies have included a large number of black participants and few have excluded participants from the normative sample with subclinical/latent neurological disease or dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2015-01-01

    The mechanical cause of age-related dementia (Alzheimer's disease): the brain is destroyed by the pulse

    ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD

    Key finding: This review traces evidence that age-related dementia (Alzheimer's disease) results from the destructive impact of the pulse on cerebral vasculature. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2015-01-01

    Morphometric and histologic substrates of cingulate integrity in elders with exceptional memory capacity

    ✓ Peer-reviewed Brain scans and imaging The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: A preliminary investigation using structural brain imaging revealed a region of anterior cingulate cortex that was thicker in SuperAgers compared with healthy 50- to 65-year-olds. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2015-01-01

    White matter changes in dementia: role of impaired drainage of interstitial fluid

    ✓ Peer-reviewed Prevention and risk Brain pathology (Zurich, Switzerland)

    Key finding: White matter abnormalities on magnetic resonance imaging (MRI) are associated with dementia and include white matter hyperintensities (WMH; also termed leukoaraiosis) and visible perivascular spaces (PVS). +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2015-01-01

    Anti-inflammatory drugs and risk of Alzheimer's disease: an updated systematic review and meta-analysis

    ✓ Peer-reviewed Prevention and risk Journal of Alzheimer's disease : JAD

    Key finding: Observational studies support the use of NSAIDs for prevention of AD, but RCT do not. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2015-01-01

    A systematic review of risk factors for delirium in the ICU

    ✓ Peer-reviewed Prevention and risk Critical care medicine

    Key finding: Only 11 putative risk factors for delirium are supported by either strong or moderate level of evidence.

    Full summary, score breakdown and related studies → Original source

  14. 2015-01-01

    Results from a Phase II Study to Assess the Clinical and Immunological Activity of AFFITOPE® AD02 in Patients with Early Alzheimer's Disease

    ✓ Peer-reviewed Treatments The journal of prevention of Alzheimer's disease

    Key finding: Treatments were generally well tolerated and adverse events (AEs) were seen at similar rates across all treatment groups, with the exception that more injection site reactions were seen in the groups with a higher level of adjuvant. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2015-01-01

    Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: Brain DNA methylation in multiple AD loci is associated with AD pathologies. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2015-01-01

    String Vessel Formation is Increased in the Brain of Parkinson Disease

    ✓ Peer-reviewed Biomarkers Journal of Parkinson's disease

    Key finding: Endothelial degeneration and preservation of basement membrane result in an increase of string vessel formation in PD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2015 no date recorded — placed by publication year

    Mediterranean Diet and Age-Related Cognitive Decline: A Randomized Clinical Trial

    ✓ Peer-reviewed Prevention and risk JAMA Internal Medicine

    Key finding: Epidemiologic studies suggest that a Mediterranean diet, an antioxidant-rich cardioprotective dietary pattern, delays cognitive decline, but clinical trial evidence is lacking. +4 more findings

    Full summary, score breakdown and related studies → Original source

December 2014 8

  1. 2014-12-31

    Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine

    ✓ Peer-reviewed Brain tissue and pathology Acta neuropathologica

    Key finding: This review focuses mainly on FTLD-Tau and FLTD-TDP, which may present as several clinical syndromes: a behavioral/dysexecutive syndrome (behavioral variant frontotemporal dementia); language disorders (primary progressive aphasia variants); and motor disorders (amyotrophic lateral sclerosis, corticobasal syndrome, progressive supranuclear palsy syndrome). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2014-12-29

    The positive aspects of caregiving in dementia: A critical review of the qualitative literature

    ✓ Peer-reviewed Caregiving Dementia (London, England)

    Key finding: A systematic search of the literature revealed 14 studies that met this aim.

    Full summary, score breakdown and related studies → Original source

  3. 2014-12-27

    A systematic review of strategies used to increase recruitment of people with cancer or organ failure into clinical trials: implications for palliative care research

    ✓ Peer-reviewed End-of-life care Journal of pain and symptom management

    Key finding: Successful strategies from other disciplines could be considered by palliative care researchers.

    Full summary, score breakdown and related studies → Original source

  4. 2014-12-26

    Low-intensity daily walking activity is associated with hippocampal volume in older adults

    ✓ Peer-reviewed Prevention and risk Hippocampus

    Key finding: Hippocampal atrophy is associated with memory impairment and dementia and serves as a key biomarker in the preclinical stages of Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2014-12-24

    Independent information from cerebrospinal fluid amyloid-β and florbetapir imaging in Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Brain : a journal of neurology

    Key finding: Cerebrospinal fluid and positron emission tomography amyloid-β were measured at baseline in 769 persons [161 healthy controls, 68 subjective memory complaints, 419 mild cognitive impairment and 121 Alzheimer's disease dementia, mean age 72 years (standard deviation 7 years), 47% females] and used to predict diagnosis, APOE ε4 carriage status, cerebral blood flow, cerebrospinal fluid total-tau and phosphorylated-tau levels (cross-sectionally); and hippocampal volume, fluorodeoxyglucose positron emission tomography results and Alzheimer's Disease Assessment Scale-cognitive subscale scores (longitudinally). +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2014-12-23

    Megacities air pollution problems: Mexico City Metropolitan Area critical issues on the central nervous system pediatric impact

    ✓ Peer-reviewed Risk factors Environmental research

    Key finding: The chronic health effects associated with sustained exposures to high concentrations of air pollutants are an important issue for millions of megacity residents and millions more living in smaller urban and rural areas.

    Full summary, score breakdown and related studies → Original source

  7. 2014-12-23

    Evaluation and management of the elderly patient presenting with cognitive complaints

    ✓ Peer-reviewed End-of-life care The Medical clinics of North America

    Key finding: Older adults should routinely be asked about any concerns about their memory or thinking, and any cognitive complaint from the patient or an informant should be evaluated rather than be attributed to aging. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2014-12-23

    A novel, ultrasensitive assay for tau: potential for assessing traumatic brain injury in tissues and biofluids

    ✓ Peer-reviewed Disease mechanisms Journal of neurotrauma

    Key finding: Pathologically, TBI results in axonal injury that is coupled to tau hyperphosphorylation, leading to microtubule instability and tau-mediated neurodegeneration. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →