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This page is alzhub.org's plain-English summary of a published study, not the paper itself. It is generated from the record we hold for this study, sourced and linked below — check the original for the full text and methods.

✓ Peer-reviewed alzhub usefulness score 64 out of 100. Inflammation and the immune system

Topic: Amyloid, tau and blood-test diagnosis

We do not hold a plain-English summary of this study yet. Use the links to the original below for its abstract and findings.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Heneka, M. T., Carson, M. J., El Khoury, J. B., Landreth, G. E., Brosseron, F., Feinstein, D. L., et al. (2015). Neuroinflammation in Alzheimer's disease. The Lancet Neurology. https://doi.org/10.1016/s1474-4422(15)70016-5

Vancouver

Heneka MT, Carson MJ, El Khoury JB, Landreth GE, Brosseron F, Feinstein DL, et al. Neuroinflammation in Alzheimer's disease. The Lancet Neurology. 2015. doi:10.1016/s1474-4422(15)70016-5. PMID: 25792098.

BibTeX

@article{heneka2015-25792098,
  author  = {Heneka, Michael Thomas and Carson, Monica J. and El Khoury, Joseph B. and Landreth, Gary E. and Brosseron, Frederic and Feinstein, Douglas L. and Jacobs, Andreas Hans and Wyss‐Coray, Tony and others},
  title   = {{Neuroinflammation in Alzheimer's disease}},
  journal = {The Lancet Neurology},
  year    = {2015},
  doi     = {10.1016/s1474-4422(15)70016-5},
  pmid    = {25792098},
  url     = {https://doi.org/10.1016/s1474-4422(15)70016-5}
}

Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.

Why it matters

Addresses neuroinflammation in Alzheimer's disease. The inflammatory side of the disease is treated as something to investigate, and no treatment is tested here.

Study details

How this study scored 64/100
How this study's score is builtJournal tier 9 of 10; Journal's citation record 3 of 4; Study design 0 of 12; Strength of evidence 1 of 5; Peer-review validation 10 of 10; How recent 1 of 5; Sample size 0 of 4; Effect reported 0 of 3; Studied in people 0 of 3; Randomised / blinded 0 of 2; Times cited 7 of 7; Citations per year 5 of 5; Impact for its field and year 6 of 6; Cited by studies here 6 of 6; Still being cited 4 of 4; Senior author's track record 2 of 4; Institution's track record 3 of 3; Multi-centre collaboration 3 of 3; Indexed in PubMed 2 of 2; Free to read 2 of 2. Total 64 of 100.64 of 100 points earned36 not earned

Published in a leading specialty journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it.

ComponentPointsWhy
Journal tier 9 / 10 Tier 2 — leading specialty journal (The Lancet Neurology)
Journal's citation record 3 / 4 The Lancet Neurology: journal h-index 457 (OpenAlex, 2026-10-29)
Study design 0 / 12 No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence 1 / 5 Rated “low” in our summary
Peer-review validation 10 / 10 Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent 1 / 5 2015 — within 20 year(s) of the newest study here
Sample size 0 / 4 Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported 0 / 3 No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people 0 / 3 Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomised / blinded 0 / 2 No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited 7 / 7 Cited 6,146 times (OpenAlex, 2026-10-10)
Citations per year 5 / 5 472.8 citations a year over 13 year(s) since 2015
Impact for its field and year 6 / 6 Cited 157.2× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here 6 / 6 Cited by 220 other studies in this library
Still being cited 4 / 4 Cited 2,048 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record 2 / 4 Last-listed author Markus P. Kummer: h-index 42 (OpenAlex, whole career)
Institution's track record 3 / 3 Harvard University: institution h-index 3,235 (OpenAlex)
Multi-centre collaboration 3 / 3 OpenAlex lists 56 institution(s) in 12 countries
Indexed in PubMed 2 / 2 Indexed in PubMed (PMID 25792098)
Free to read 2 / 2 Free to read
Total 64 / 100 —

What each of these 20 components measures, and what this score is not →

Read the original

Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).

Studies this one cites

Referenced by this study and also in the alzhub library, so you can read them here. Showing 12 of 48.

Later studies that cite this one

220 studies in the alzhub library list this one in their references. Showing the 8 highest-scoring.

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