Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 4,601–4,625 of 27,380 studies, newest first · page 185 of 1096.
April 2025 25
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2025-04-16
Risk-Based Primary Prevention of Heart Failure: A Scientific Statement From the American Heart Association
49/100 ✓ Peer-reviewed Prevention and risk Circulation
Key finding: Third, the predominant phenotype of HF risk has emerged as the cardiovascular-kidney-metabolic syndrome. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-16
Association of Nonmodifiable Risk Factors With Alzheimer Disease Blood Biomarkers in Community-Dwelling Adults in the ESTHER Study
62/100 ✓ Peer-reviewed Tau biomarkers Neurology
Key finding: Dementia-related blood biomarkers are the future of large-scale dementia risk stratification; however, the extent to which phosphorylated tau (P-tau181), neurofilament light (NfL), and glial fibrillary acidic protein (GFAP) are associated with nonmodifiable risk factors has yet to be confirmed in the community, and the role of menopause has yet to be investigated. +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-15
Exploring the efficacy and safety of lecanemab in the management of early Alzheimer's disease: A systematic review of clinical evidence
66/100 ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD
Key finding: The common infusion-related reactions were observed in 26.4% of the lecanemab group compared to 7% in the placebo group.
Full summary, score breakdown and related studies → Original source
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2025-04-15
WMH ‐ DualTasker : A Weakly Supervised Deep Learning Model for Automated White Matter Hyperintensities Segmentation and Visual Rating Prediction
48/100 ✓ Peer-reviewed Vascular contributions Human Brain Mapping
Key finding: The volumetric quantification performance of WMH-DualTasker was either superior to or on par with existing supervised methods, as demonstrated on the MICCAI-WMH dataset (N = 60, Dice = 0.602) and the SINGER dataset (N = 64, Dice = 0.608). +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-04-15
Advance Care Planning and Unlimited Treatment Preferences in Dementia Scenarios: Insights From Community-Dwelling Adults
38/100 ✓ Peer-reviewed End-of-life care American Journal of Hospice and Palliative Medicine®
Key finding: In the dementia scenario, 26.9% of participants preferred unlimited medical treatment. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-15
A structural haplotype in the 17q21.31 MAPT region is associated with increased risk for chronic traumatic encephalopathy endophenotypes
41/100 ✓ Peer-reviewed Disease mechanisms Cell Reports Medicine
Key finding: Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with repetitive head impact (RHI) exposure. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-15
Potential Benefits of Quercetin through P2X7 Modulation against Neuroinflammation in Alzheimer's Disease
35/100 ✓ Peer-reviewed Inflammation and the immune system Current Neuropharmacology
Key finding: Therefore, we believe that Quercetin may have significant power in modulating the P2X7 receptor, demonstrating that the purinergic system has the potential to modulate neuroinflammation and can add to the treatment, reduce disease progression, and result in better prognoses.
Full summary, score breakdown and related studies → Original source
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2025-04-15
Volumetric Changes in Cerebellar Transverse Zones: Age and Sex Effects in Health and Neurological Disorders
51/100 ✓ Peer-reviewed Brain scans and imaging Human Brain Mapping
Key finding: Significant age-dependent volume reductions were observed across transverse zones, with the central zone (CZ; lobules VI and VII) exhibiting the steepest decline in both health and neurological disorders. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-15
Informant accuracy of IQCODE, AD8 and GPCOGi for diagnosis of dementia: does your friend know best?
42/100 ✓ Peer-reviewed Getting a diagnosis BMC Family Practice
Key finding: Of 238 participants with informant data, 131 had dementia, 60 had CIND, and 47 had normal cognition. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-15
Assessing Cognitive Impairment in the Health and Retirement Study Harmonized Cognitive Assessment Protocol Project: Comparing a Diagnostic Algorithm With a Diagnostic Consensus Panel
38/100 ✓ Peer-reviewed Getting a diagnosis Journal of Aging and Health
Key finding: BackgroundAccurate classification of cognitive impairment in population studies is challenging. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-15
Dose-response relationship between evening exercise and sleep
54/100 ✓ Peer-reviewed Prevention and risk Nature Communications
Key finding: Here we show later exercise timing and higher exercise strain are associated with delayed sleep onset, shorter sleep duration, lower sleep quality, higher nocturnal resting heart rate, and lower nocturnal heart rate variability. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-15
A Review of Clinical Biomarker Insights: Advances in Diagnosis and Prognosis of Early Alzheimer
27/100 ✓ Peer-reviewed Biomarkers Global Journal of Medical Pharmaceutical and Biomedical Update
Key finding: This review primarily addresses the methods used in the study, which was published in the journal Nature Aging, to measure biomarkers using fludeoxyglucose positron emission tomography, single molecule array, cerebospinal fluid sampling and blood proteomics, and dementia investigation to date. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-15
Dissection of blood-brain barrier dysfunction through CSF PDGFRβ and amyloid, tau, neuroinflammation, and synaptic CSF biomarkers in neurodegenerative disorders
51/100 ✓ Peer-reviewed Biomarkers EBioMedicine
Key finding: Comparing clinical stages, CSF PDGFRβ levels were increased at the MCI stage (Cohen's d = 0.55 [CI 95% 0.066, 1.0], P = 0.025) compared with NC. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-14
Human oral microbiome and its influence on mental health and brain disorders
43/100 ✓ Peer-reviewed Disease mechanisms AIMS microbiology
Key finding: This pathway can lead to neuroinflammation and cognitive dysfunction and contribute to adverse mental health effects. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-14
Conversion to Mild Cognitive Impairment and Alzheimer’s Disease Dementia Related to Apathy, APOE Genotype and Antidepressant Use
31/100 ✓ Peer-reviewed Mild cognitive impairment Journal of Geriatric Psychiatry and Neurology
Key finding: Our findings support apathy and APOE ε4 as robust predictors of conversion to MCI and ADD, and demonstrate novel associations between antidepressant use and conversion. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-14
Standardizing Number of EEG Sensors for AI-Driven Dementia Detection
38/100 ✓ Peer-reviewed Digital health tools IEEE Sensors Letters
Key finding: Artificial Intelligence (AI) has gained significant attention for AD detection, particularly through Electroencephalography (EEG)—a cost-effective, accessible technique that records brain activity from sensors placed on the scalp. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-04-14
“But Then They Don’t Use the Same Money to Give Us Services”: Attitudes and Perspectives on Dementia Care Community-Based Research in Hispanic Communities
44/100 ✓ Peer-reviewed Disparities Journal of Applied Gerontology
Key finding: This paper discusses attitudes and perspectives on participating in community-based dementia-support interventions using a focus group methodology of Hispanic/Latino staff ( n = 5). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-14
Post-diagnostic support in Australia: Perspectives of people recently diagnosed with dementia and their carers
46/100 ✓ Peer-reviewed Caregiving Dementia
Key finding: Current Care and Support: Four themes emerged: Communication with empathy; Written information valuable but could be overwhelming; Referrals provided but not necessarily followed; A focus on prescribed anti-dementia medications. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-14
Transforming Disaster Risk Reduction With AI and Big Data: Legal and Interdisciplinary Perspectives
43/100 ✓ Peer-reviewed Prevention and risk Wiley Interdisciplinary Reviews Data Mining and Knowledge Discovery
Key finding: Managing complex disaster risks requires interdisciplinary efforts. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-14
Risk Factors Associated With Late-Onset Epilepsy in Dementia and Mild Cognitive Impairment
65/100 ✓ Peer-reviewed Prevention and risk JAMA Neurology
Key finding: Of the 14 685 participants (7355 female [50%] and 7330 male [50%]; mean [SD] age, 73.8 [8.5] years) who met the inclusion criteria, 221 participants (1.5%) developed LOE during follow-up. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-14
Anti-Amyloid Monoclonal Antibodies for the Treatment of Alzheimer Disease: Intersocietal Recommendations for Their Appropriate Use in Switzerland
41/100 ✓ Peer-reviewed Treatments Neurodegenerative Diseases
Key finding: The recommendations are the result of extensive interdisciplinary discussions in a group of Swiss dementia experts from August 2023 until December 2024.
Full summary, score breakdown and related studies → Original source
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2025-04-14
Disparities in High-Risk Medication Use—Implications for Health Equity and Deprescribing Practices
36/100 ✓ Peer-reviewed Health systems and care delivery JAMA Network Open
Key finding: Potentially inappropriate medication (PIM) use-defined as the use of high-risk medications that can increase the risk of adverse events such as physical, cognitive, and functional decline; delirium; hospitalizations; and mortality-remains a significant concern in older adults in the US.Numerous guid
Full summary, score breakdown and related studies → Original source
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2025-04-14
Racial and Ethnic Differences in Potentially Inappropriate Medication Use Among Medicare Beneficiaries
52/100 ✓ Peer-reviewed Health systems and care delivery JAMA Network Open
Key finding: The study sample included 21 193 170 patients with 32 199 587 beneficiary-year observations (mean [SD] age, 75.5 [7.3] years; 18 936 697 [58.8%] female; 983 513 [3.1%] Asian or Pacific Islander, 3 190 515 [9.9%] Black, 2 710 930 [8.4%] Hispanic, and 25 314 629 [78.6%] White). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-13
Hybrid of DSR-GAN and CNN for Alzheimer disease detection based on MRI images
44/100 ✓ Peer-reviewed Brain scans and imaging Scientific Reports
Key finding: The CNN model undergoes hyperparameter optimization and incorporates data augmentation strategies to maximize its efficiency. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-13
Fatal Hip Fractures From Accidental Falls From a Ground-Level Fall
38/100 ✓ Peer-reviewed Risk factors Academic Forensic Pathology
Key finding: The Area Deprivation Index (ADI) was not associated with sex, race, medical conditions determined to have contributed to death, whether the patient underwent surgery, or with any surgical complication. +1 more finding
Full summary, score breakdown and related studies → Original source
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