Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 16,326–16,350 of 27,380 studies, newest first · page 654 of 1096.
February 2016 25
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2016-02-04
Noise induced hearing loss impairs spatial learning/memory and hippocampal neurogenesis in mice
40/100 ✓ Peer-reviewed Risk factors Scientific reports
Key finding: Hearing loss has been associated with cognitive decline in the elderly and is considered to be an independent risk factor for dementia. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-04
Encountering aged care: a mixed methods investigation of medical students' clinical placement experiences
47/100 ✓ Peer-reviewed End-of-life care BMC geriatrics
Key finding: Pre-placement surveys identified good dementia knowledge, but poor attitudes towards aged care and older adults. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-04
Advance care planning in motor neuron disease: A qualitative study of caregiver perspectives
43/100 ✓ Peer-reviewed End-of-life care Palliative medicine
Key finding: Advance care planning can assist patients to achieve a sense of control and 'peace of mind' and facilitates important family discussion. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-02-04
Subjective memory decline predicts greater rates of clinical progression in preclinical Alzheimer's disease
48/100 ✓ Peer-reviewed Caregiving Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: High SMD is a harbinger of greater rates of clinical progression in preclinical AD. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-04
Behavioural Risk Factors in Mid-Life Associated with Successful Ageing, Disability, Dementia and Frailty in Later Life: A Rapid Systematic Review
62/100 ✓ Peer-reviewed Prevention and risk PloS one
Key finding: This search located 10,338 individual references, of which 164 are included in this review. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-02-03
Palliative and end of life care for people with dementia
38/100 ✓ Peer-reviewed End-of-life care Nursing standard (Royal College of Nursing (Great Britain) : 1987)
Key finding: As a result, people with dementia at the end of life often receive aggressive and burdensome interventions, or inadequate assessment and management of their symptoms.
Full summary, score breakdown and related studies → Original source
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2016-02-03
The glucagon-like peptide 1 (GLP) receptor as a therapeutic target in Parkinson's disease: mechanisms of action
36/100 ✓ Peer-reviewed Drug development Drug discovery today
Key finding: Growing evidence suggests that agonists of the glucagon-like peptide 1 (GLP-1) receptor provide neuroprotection across a range of experimental models of Parkinson's disease (PD) and, recently, a small proof-of-concept, open-label human trial of exenatide in the treatment moderate severity PD appeared to show persistent improvements in motor and cognitive function.
Full summary, score breakdown and related studies → Original source
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2016-02-03
Heterogeneous histopathology of cortical microbleeds in cerebral amyloid angiopathy
50/100 ✓ Peer-reviewed Brain scans and imaging Neurology
Key finding: This study provides evidence for heterogeneous pathologic substrates and possibly different pathophysiologic mechanisms underlying MRI-observed cortical microbleeds in the context of advanced CAA and Alzheimer disease.
Full summary, score breakdown and related studies → Original source
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2016-02-03
Amyloid pathology and axonal injury after brain trauma
52/100 ✓ Peer-reviewed Brain scans and imaging Neurology
Key finding: Increased Aβ burden was observed in TBI. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-02-02
Depression and postoperative complications: an overview
40/100 ✓ Peer-reviewed Clinical safety BMC surgery
Key finding: Depression is a frequent cause of morbidity in surgery patients suffering from a wide range of conditions. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-02
Molecular Pathological Classification of Neurodegenerative Diseases: Turning towards Precision Medicine
51/100 ✓ Peer-reviewed Brain tissue and pathology International journal of molecular sciences
Key finding: These proteins and their biochemical modifications can be potentially targeted for therapy or used as biomarkers. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-02 month only
Late-life depression is not associated with dementia-related pathology
68/100 ✓ Peer-reviewed Risk factors Neuropsychology
Key finding: In the full cohort, 9.4% were diagnosed with major depression and 8.6% had chronically elevated depressive symptoms, both of which were related to adverse cognitive outcomes. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-01
Preinjury physical frailty and cognitive impairment among geriatric trauma patients determine postinjury functional recovery and survival
45/100 ✓ Peer-reviewed Clinical safety The journal of trauma and acute care surgery
Key finding: Preinjury physical frailty is the predominant predictor of postinjury functional status and mortality in geriatric trauma patients. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-01
The Differential Diagnosis and Treatment of Atypical Parkinsonism
40/100 ✓ Peer-reviewed Clinical safety Deutsches Arzteblatt international
Key finding: Causal treatments for neurodegenerative diseases are now being developed and tested, and thus a molecular diagnosis is desirable.
Full summary, score breakdown and related studies → Original source
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2016-02-01
The Healthy Mind, Healthy Mobility Trial: A Novel Exercise Program for Older Adults
72/100 ✓ Peer-reviewed Prevention trials Medicine and science in sports and exercise
Key finding: A 26-wk group-based exercise program combined with dual-task training improved GCF in community-dwelling older adults without dementia. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-01
Antipsychotic Use in Hospitalized Adults: Rates, Indications, and Predictors
69/100 ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society
Key finding: Antipsychotic initiation and use were common during hospitalization, most often for delirium, and individuals were frequently discharged on these medications. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-01
Regulatory T cells delay disease progression in Alzheimer-like pathology
54/100 ✓ Peer-reviewed Inflammation and the immune system Brain : a journal of neurology
Key finding: Vaccines targeting amyloid-β peptide provided encouraging results in mouse models, but severe side effects attributed to T cell responses in the first clinical trial AN1792 underlined the need for better understanding adaptive immunity in Alzheimer's disease. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-01
The Cellular Phase of Alzheimer's Disease
57/100 ✓ Peer-reviewed Inflammation and the immune system Cell
Key finding: This direct causality is incompatible with clinical observations. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-01
Altered Mitochondrial DNA Methylation Pattern in Alzheimer Disease-Related Pathology and in Parkinson Disease
42/100 ✓ Peer-reviewed Risk genes beyond APOE The American journal of pathology
Key finding: Mitochondria are intracellular organelles essential for cell viability and are characterized by the presence of the mitochondrial (mt)DNA. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-01
Assessment of Mental Status
38/100 ✓ Peer-reviewed Digital health tools Neurologic clinics
Key finding: A second type of assessment utilizes what may be termed as "screening tests" or "omnibus tests". +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-01
Impaired Cognition and Brain Atrophy Decades After Hypertensive Pregnancy Disorders
50/100 ✓ Peer-reviewed Digital health tools Circulation. Cardiovascular quality and outcomes
Key finding: Hypertensive pregnancy disorders are associated with worse performance on tests of processing speed and smaller brain volumes decades later. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-01
Hypertension and aging
43/100 ✓ Peer-reviewed How common it is Ageing research reviews
Key finding: The objective of the present review is to highlight the multi-dimensional risks of hypertension among older adults and discuss potential strategies for treatment and future areas of research for improving overall care for older adults with hypertension.
Full summary, score breakdown and related studies → Original source
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2016-02-01
Dexmedetomidine versus Propofol Sedation Reduces Delirium after Cardiac Surgery: A Randomized Controlled Trial
70/100 ✓ Peer-reviewed Prevention and risk Anesthesiology
Key finding: When compared with propofol, dexmedetomidine sedation reduced incidence, delayed onset, and shortened duration of POD in elderly patients after cardiac surgery. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-01
Incidence of Dementia over Three Decades in the Framingham Heart Study
69/100 ✓ Peer-reviewed Prevention and risk The New England journal of medicine
Key finding: Among participants in the Framingham Heart Study, the incidence of dementia has declined over the course of three decades. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-02-01
Routine cognitive screening in a neurology practice: Effect on physician behavior
35/100 ✓ Peer-reviewed Treatments Neurology. Clinical practice
Key finding: There was a 37.4% screen positive rate on the Mini-Cog. +1 more finding
Full summary, score breakdown and related studies → Original source
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