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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 16,101–16,125 of 27,380 studies, newest first · page 645 of 1096.

May 2016 7

  1. 2016-05-01

    Diagnostic and Prognostic Utility of the Synaptic Marker Neurogranin in Alzheimer Disease

    ✓ Peer-reviewed Tau biomarkers JAMA neurology

    Key finding: Synaptic loss is an early pathologic substrate of Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-05-01

    TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

    ✓ Peer-reviewed TREM2 and immune genetics Neuron

    Key finding: To investigate this, we used high-resolution confocal and super-resolution (STORM) microscopy in AD-like mice and human AD tissue. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2016-05-01

    Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease

    ✓ Peer-reviewed How common it is Science translational medicine

    Key finding: Multivariate analyses identified unique disease-related stereotypical spatial patterns (topographies) for deposition of tau and Aβ. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2016-05-01

    Racial Disparities in Cognitive Performance in Mid- and Late Adulthood: Analyses of Two Cohort Studies

    ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society

    Key finding: Attenuation of racial inequalities in older age can be extended to cognitive outcomes, which probably reflects selective survival.

    Full summary, score breakdown and related studies → Original source

  5. 2016-05-01

    Trajectories of Depressive Symptoms in Older Adults and Risk of Dementia

    ✓ Peer-reviewed Disparities JAMA psychiatry

    Key finding: The analytic cohort included 2488 black and white older adults with repeated depressive symptom assessments from baseline to year 5 who were free of dementia throughout that period. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2016-05-01

    Mini-Mental State Examination in Elderly Chinese: A Population-Based Normative Study

    ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD

    Key finding: It could be of great improvement for the use of the MMSE in dementia screening in Chinese elderly population.

    Full summary, score breakdown and related studies → Original source

  7. 2016-05-01

    Brain in Congenital Heart Disease Across the Lifespan: The Cumulative Burden of Injury

    ✓ Peer-reviewed Caregiving Circulation

    Key finding: Together with altered cerebral perfusion in utero, these factors are associated with abnormalities of brain structure and brain immaturity in a significant portion of neonates with critical CHD even before they undergo cardiac surgery.

    Full summary, score breakdown and related studies → Original source

April 2016 18

  1. 2016-04-29

    Trends in the Incidence of Parkinson Disease in the General Population: The Rotterdam Study

    ✓ Peer-reviewed Long-term cohort studies American journal of epidemiology

    Key finding: From the baseline years, we observed differences in the second subcohort that were associated with a lower risk of PD for some but not all baseline risk factors. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-04-29

    10-year trajectories of depressive symptoms and risk of dementia: a population-based study

    ✓ Peer-reviewed Long-term cohort studies The lancet. Psychiatry

    Key finding: Late-life depressive symptoms have been extensively studied for their relationship with incident dementia, but have been typically assessed at a single timepoint. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2016-04-29

    Obstructive Sleep Apnea is Linked to Depression and Cognitive Impairment: Evidence and Potential Mechanisms

    ✓ Peer-reviewed Risk factors The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Hypoxemia exacerbates these processes, resulting in white matter lesions, white matter integrity abnormalities, and gray matter loss. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2016-04-29

    Short-Term Effects of a Gain-Focused Reappraisal Intervention for Dementia Caregivers: A Double-Blind Cluster-Randomized Controlled Trial

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Finding positive gains reduces depressive symptoms and burden and promotespsychological well-being primarily through enhancing self-efficacy in controlling upsetting thoughts. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2016-04-28

    Remote Physical Activity Monitoring in Neurological Disease: A Systematic Review

    ✓ Peer-reviewed Clinical safety PloS one

    Key finding: These studies show that remote physical activity monitoring is feasible in neurological diseases, including in people with moderate to severe neurological disability. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2016-04-28

    Dementia risk after spontaneous intracerebral haemorrhage: a prospective cohort study

    ✓ Peer-reviewed Brain tissue and pathology The Lancet. Neurology

    Key finding: Dementia occurs in at least 10% of patients within 1 year after stroke. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2016-04-27

    Subcutaneous administration of liraglutide ameliorates learning and memory impairment by modulating tau hyperphosphorylation via the glycogen synthase kinase-3β pathway in an amyloid β protein induced alzheimer disease mouse model

    ✓ Peer-reviewed Drug development European journal of pharmacology

    Key finding: The results showed that subcutaneous administration of liraglutide (25nmol/day), once daily for 8 weeks, prevented memory impairments in the Y Maze and Morris Water Maze following Aβ1-42 intracerebroventricular injection, and alleviated the ultra-structural changes of pyramidal neurons and chemical synapses in the hippocampal CA1 region.

    Full summary, score breakdown and related studies → Original source

  8. 2016-04-27

    Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9

    ✓ Peer-reviewed Risk genes beyond APOE Nature

    Key finding: Our findings enable efficient introduction of specific sequence changes with CRISPR/Cas9, facilitating study of human disease.

    Full summary, score breakdown and related studies → Original source

  9. 2016-04-27

    (11)C-PBR28 binding to translocator protein increases with progression of Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Neurobiology of aging

    Key finding: The annual rate of increased TSPO binding in temporoparietal regions was about 5-fold higher in patients with clinical progression (n = 9) compared with those who did not progress (n = 5).

    Full summary, score breakdown and related studies → Original source

  10. 2016-04-27

    Cerebrospinal fluid soluble TREM2 in aging and Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Alzheimer's research & therapy

    Key finding: Alzheimer's disease (AD) neuropathology is associated with neuroinflammation, but there are few useful biomarkers. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2016-04-27

    White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: Autosomal-dominant AD is associated with increased WMH well before expected symptom onset. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2016-04-26

    Cognitive Reserve in Dementia: Implications for Cognitive Training

    ✓ Peer-reviewed Prevention trials Frontiers in aging neuroscience

    Key finding: Multiple linear regression analyses highlighted CR as a significant factor able to predict changes in cognitive performance after the CT.

    Full summary, score breakdown and related studies → Original source

  13. 2016-04-26

    Decreased peripheral brain-derived neurotrophic factor levels in Alzheimer's disease: a meta-analysis study (N=7277)

    ✓ Peer-reviewed Mild cognitive impairment Molecular psychiatry

    Key finding: Studies suggest that dysfunction of brain-derived neurotrophic factor (BDNF) is a possible contributor to the pathology and symptoms of Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2016-04-26

    Prevalence and incidence of Alzheimer's disease in Europe: A meta-analysis

    ✓ Peer-reviewed How common it is Neurologia (Barcelona, Spain)

    Key finding: The results of our meta-analysis allow a better grasp of the impact of this disease in Europe. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2016-04-26

    Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology

    ✓ Peer-reviewed Genetics Molecular psychiatry

    Key finding: These data indicate that PTK2B acts as an early marker and in vivo modulator of Tau toxicity.

    Full summary, score breakdown and related studies → Original source

  16. 2016-04-25

    Poorer outcomes and greater healthcare costs for hospitalised older people with dementia and delirium: a retrospective cohort study

    ✓ Peer-reviewed Digital health tools International journal of geriatric psychiatry

    Key finding: Hospitalised people with cognitive impairment experience significantly greater length of stay and when discharged to their usual residence are more likely to be readmitted to hospital within 28 days compared with those without cognitive impairment. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2016-04-25

    One for All? Hitting Multiple Alzheimer's Disease Targets with One Drug

    ✓ Peer-reviewed Drug development Frontiers in neuroscience

    Key finding: Repurposing current drugs using their off-target effects reduces the cost of development, time to launch, and the uncertainty associated with safety and pharmacokinetics.

    Full summary, score breakdown and related studies → Original source

  18. 2016-04-25

    Preschool is a sensitive period for the influence of maternal support on the trajectory of hippocampal development

    ✓ Peer-reviewed Hippocampus size on brain scans Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Building on well-established animal data demonstrating the effects of early maternal support on hippocampal development and adaptive coping, a few longitudinal studies suggest that early caregiver support also impacts human hippocampal development. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →