Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 14,851–14,875 of 27,380 studies, newest first · page 595 of 1096.
August 2017 20
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2017-08-02
TREM2 in Neurodegenerative Diseases
53/100 ✓ Peer-reviewed TREM2 and immune genetics Molecular neurodegeneration
Key finding: Because TREM2 encodes a receptor exclusively expressed on immune cells, identification of these variants conclusively demonstrates that the immune response can play an active role in the pathogenesis of NDDs. +3 more findings
Full summary, score breakdown and related studies → Original source
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2017-08-01
Sleep Disturbance, Cognitive Decline, and Dementia: A Review
41/100 ✓ Peer-reviewed Brain scans and imaging Seminars in Neurology
Key finding: Approximately half of older people report sleep disturbances, which are associated with various health conditions, including neurodegenerative disease and dementia. +2 more findings
Full summary, score breakdown and related studies → Original source
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2017-08-01
State Regulatory Approaches for Dementia Care in Residential Care and Assisted Living
39/100 ✓ Peer-reviewed Health systems and care delivery The Gerontologist
Key finding: Sixteen states license or certify dementia care units within RC/AL settings. +4 more findings
Full summary, score breakdown and related studies → Original source
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2017-08 month only
Circadian Rhythm Sleep-Wake Disorders
39/100 ✓ Peer-reviewed Risk factors Continuum (Minneapolis, Minn.)
Key finding: The endogenous circadian rhythms are one of the cardinal processes that control sleep. +4 more findings
Full summary, score breakdown and related studies → Original source
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2017-08 month only
Practical applications of physical activity for successful cognitive aging
39/100 ✓ Peer-reviewed Prevention trials JAAPA : official journal of the American Academy of Physician Assistants
Key finding: As patients lose cognitive function, they lose autonomy and increasingly use fiscal, social, and medical resources. +4 more findings
Full summary, score breakdown and related studies → Original source
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2017-08 month only
Metformin and Alzheimer's disease, dementia and cognitive impairment: a systematic review protocol
39/100 ✓ Peer-reviewed Drug development JBI database of systematic reviews and implementation reports
Key finding: The objective of the review is to assess the effect of metformin on the risk, progression and severity of Alzheimer's disease and other forms of dementia, as well as any measures of cognitive performance or impairment.
Full summary, score breakdown and related studies → Original source
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2017-08-01
Association of Autonomic Dysfunction With Disease Progression and Survival in Parkinson Disease
53/100 ✓ Peer-reviewed Digital health tools JAMA neurology
Key finding: Earlier AutD is associated with a more rapid development of disease milestones and shorter survival in patients with PD. +4 more findings
Full summary, score breakdown and related studies → Original source
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2017-08-01
Anti-Alzheimer Properties of Probiotic, Lactobacillus plantarum MTCC 1325 in Alzheimer's Disease induced Albino Rats
38/100 ✓ Peer-reviewed Disease mechanisms Journal of clinical and diagnostic research : JCDR
Key finding: The study revealed that, L. plantarum MTCC1325 might have anti-Alzheimer properties against D-Galactose induced Alzheimer's disease. +2 more findings
Full summary, score breakdown and related studies → Original source
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2017-08-01
APP mouse models for Alzheimer's disease preclinical studies
41/100 ✓ Peer-reviewed Risk genes beyond APOE The EMBO journal
Key finding: Animal models of human diseases that accurately recapitulate clinical pathology are indispensable for understanding molecular mechanisms and advancing preclinical studies. +4 more findings
Full summary, score breakdown and related studies → Original source
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2017-08-01
Slow wave sleep disruption increases cerebrospinal fluid amyloid-β levels
41/100 ✓ Peer-reviewed Tau biomarkers Brain : a journal of neurology
Key finding: (doi:10.1093/awx174) for a scientific commentary on this article. +2 more findings
Full summary, score breakdown and related studies → Original source
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2017-08-01
Preoperative Cognitive Performance and Postoperative Delirium Are Independently Associated With Future Dementia in Older People Who Have Undergone Cardiac Surgery: A Longitudinal Cohort Study
69/100 ✓ Peer-reviewed Clinical safety Critical care medicine
Key finding: Our findings suggest that older patients with reduced preoperative cognitive functions or who develop postoperative delirium are at risk of developing dementia within 5 years after cardiac surgery. +3 more findings
Full summary, score breakdown and related studies → Original source
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2017-08-01
Postoperative delirium in elderly patients is associated with subsequent cognitive impairment
52/100 ✓ Peer-reviewed Clinical safety British journal of anaesthesia
Key finding: Mild cognitive impairment or dementia is a risk for POD. +3 more findings
Full summary, score breakdown and related studies → Original source
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2017-08-01
Nutrient intake and dietary changes during a 2-year multi-domain lifestyle intervention among older adults: secondary analysis of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) randomised controlled trial
74/100 ✓ Peer-reviewed Prevention trials The British journal of nutrition
Key finding: The difference in change compared with the control group was significant at both years (P<0·001 and P=0·018).
Full summary, score breakdown and related studies → Original source
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2017-08-01
Tea, talk and technology: patient and public involvement to improve connected health ‘wearables’ research in dementia
45/100 ✓ Peer-reviewed Health systems and care delivery Research Involvement and Engagement
Key finding: Discussions revealed that people were generally supportive of this type of research, provided they gave informed consent and that devices were discreet, comfortable and easy to use. +3 more findings
Full summary, score breakdown and related studies → Original source
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2017-08-01
TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease
59/100 ✓ Peer-reviewed TREM2 and immune genetics Cell
Key finding: How TREM2 promotes such diverse responses is unknown. +3 more findings
Full summary, score breakdown and related studies → Original source
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2017-08-01
Cerebral quantitative susceptibility mapping predicts amyloid-β-related cognitive decline
57/100 ✓ Peer-reviewed Mild cognitive impairment Brain : a journal of neurology
Key finding: See Derry and Kent (doi:10.1093/awx167) for a scientific commentary on this article. +1 more finding
Full summary, score breakdown and related studies → Original source
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2017-08-01
Imaging plus X: multimodal models of neurodegenerative disease
55/100 ✓ Peer-reviewed Digital health tools Current opinion in neurology
Key finding: These models have revealed insights into frontotemporal dementia, Huntington's disease, multiple sclerosis, Parkinson's disease and other conditions. +3 more findings
Full summary, score breakdown and related studies → Original source
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2017-08-01
Association Between Persistent Pain and Memory Decline and Dementia in a Longitudinal Cohort of Elders
64/100 ✓ Peer-reviewed How common it is JAMA internal medicine
Key finding: Persistent pain was associated with accelerated memory decline and increased probability of dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
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2017-08-01
TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics
58/100 ✓ Peer-reviewed Caregiving Neuron
Key finding: Subsequent genetic association analyses showed an increased burden of TIA1 LCD mutations in ALS patients compared to controls (p = 8.7 × 10 -6 ). +1 more finding
Full summary, score breakdown and related studies → Original source
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2017-08-01
Mediterranean diet and cognitive health: Initial results from the Hellenic Longitudinal Investigation of Ageing and Diet
69/100 ✓ Peer-reviewed Prevention and risk PloS one
Key finding: Our results suggest that adherence to the MeDi is associated with better cognitive performance and lower dementia rates in Greek elders. +4 more findings
Full summary, score breakdown and related studies → Original source
July 2017 5
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2017-07-31
Evaluation of Apolipoprotein E Fragmentation as a Biomarker for Alzheimer's Disease
43/100 ✓ Peer-reviewed Genetics Journal of neurology and neurological disorders
Key finding: Recent studies have supported a role for the proteolytic cleavage of apolipoprotein E4 (APOE4) as a potential mechanism for the enhanced dementia risk associated with Alzheimer's disease. +4 more findings
Full summary, score breakdown and related studies → Original source
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2017-07-28
Sleep and Alzheimer's disease: A pivotal role for the suprachiasmatic nucleus
39/100 ✓ Peer-reviewed Risk factors Sleep medicine reviews
Key finding: Studies suggest that these circadian disturbances form the root of sleep-wake problems, diagnosed in more than half of AD patients. +1 more finding
Full summary, score breakdown and related studies → Original source
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2017-07-28
Neuroprotective Actions of Dietary Choline
41/100 ✓ Peer-reviewed Genetics Nutrients
Key finding: High choline intake during gestation and early postnatal development in rat and mouse models improves cognitive function in adulthood, prevents age-related memory decline, and protects the brain from the neuropathological changes associated with Alzheimer's disease (AD), and neurological damage associated with epilepsy, fetal alcohol syndrome, and inherited conditions such as Down and Rett syndromes. +1 more finding
Full summary, score breakdown and related studies → Original source
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2017-07-28
Differential role of CSF fatty acid binding protein 3, α-synuclein, and Alzheimer's disease core biomarkers in Lewy body disorders and Alzheimer's dementia
57/100 ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy
Key finding: The combination of CSF biomarkers linked to different aspects of neurodegeneration, such as FABP3, α-syn, and AD biomarkers, improves the biochemical characterization of AD and Lewy body disorders. +3 more findings
Full summary, score breakdown and related studies → Original source
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2017-07-28
Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study
69/100 ✓ Peer-reviewed Hippocampus size on brain scans Annals of the rheumatic diseases
Key finding: Risk of dementia, especially vascular or mixed dementia, may be increased with high SUA levels in elderly people. +2 more findings
Full summary, score breakdown and related studies → Original source
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