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66/100

✓ Peer-reviewed alzhub usefulness score 66 out of 100. Brain tissue and pathology

Topic: Risk, prevention and care in population studies

Plain-language summary

Background Dementia occurs in at least 10% of patients within 1 year after stroke. However, the risk of dementia after spontaneous intracerebral haemorrhage that accounts for about 15% of all strokes has not been investigated in prospective studies. We aimed to determine the incidence of dementia and risk factors after an intracerebral haemorrhage.

What this study adds

Evidence grade: Moderate

This is a follow-up (cohort) study of 218 participants. This prospective cohort study measured the incidence of dementia and its risk factors after spontaneous intracerebral haemorrhage, a type of stroke not previously studied prospectively for this outcome. It describes risk after a stroke and does not test a treatment, cure or prevention for Alzheimer's disease.

Taken from this record’s own fields, not from reading the paper. The grade is assigned from the abstract’s wording; what that means.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Moulin, S., Labreuche, J., Bombois, S., Rossi, C., Boulouis, G., Hénon, H., et al. (2016). Dementia risk after spontaneous intracerebral haemorrhage: a prospective cohort study. The Lancet. Neurology. https://doi.org/10.1016/s1474-4422(16)00130-7

Vancouver

Moulin S, Labreuche J, Bombois S, Rossi C, Boulouis G, Hénon H, et al. Dementia risk after spontaneous intracerebral haemorrhage: a prospective cohort study. The Lancet. Neurology. 2016. doi:10.1016/s1474-4422(16)00130-7. PMID: 27133238.

BibTeX

@article{moulin2016-27133238,
  author  = {Moulin, S. and Labreuche, J. and Bombois, S. and Rossi, C. and Boulouis, G. and Hénon, H. and Duhamel, A. and Leys, D. and others},
  title   = {{Dementia risk after spontaneous intracerebral haemorrhage: a prospective cohort study}},
  journal = {The Lancet. Neurology},
  year    = {2016},
  doi     = {10.1016/s1474-4422(16)00130-7},
  pmid    = {27133238},
  url     = {https://doi.org/10.1016/s1474-4422(16)00130-7}
}

Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.

How to read this study

Design: this is a follow-up (cohort) study. People are observed over time and not assigned to anything, so an association can reflect other differences between groups. Look at how long follow-up lasted, how many dropped out, and whether the authors adjusted for age, education and other health conditions.
Size: the record lists 218 participants. Ask whether that is enough for the question, and who they were.
Effect: the record gives no effect size, so the summary above cannot say how large any difference was.

What the evidence grade means here

This page is graded moderate. alzhub.org assigns the grade automatically from keywords in the abstract, not from reading the paper. Moderate means the abstract mentions a cohort, case-control or longitudinal design. It can add at most 5 of the 100 points in the study score, and it is a label about design, not a verdict on whether the findings are true.

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Key findings

However, the risk of dementia after spontaneous intracerebral haemorrhage that accounts for about 15% of all strokes has not been investigated in prospective studies.
We aimed to determine the incidence of dementia and risk factors after an intracerebral haemorrhage.
Methods We did a prospective observational cohort study in patients with spontaneous intracerebral haemorrhage from the Prognosis of Intracerebral Haemorrhage (PITCH) cohort who were admitted to Lille University Hospital, Lille, France.
We included patients aged 18 years and older with parenchymal haemorrhage on the first CT scan.

Why it matters

This prospective cohort study measured the incidence of dementia and its risk factors after spontaneous intracerebral haemorrhage, a type of stroke not previously studied prospectively for this outcome. It describes risk after a stroke and does not test a treatment, cure or prevention for Alzheimer's disease.

Study details

Study designcohort study
Participants218
Evidence strengthModerate

How this study scored 66/100

Published in a leading specialty journal, and it is a cohort study following people over time. Scored zero for effect reported and randomized / blinded because the record does not state it.

Component	Points	Why
Journal tier	9 / 10	Tier 2 — leading specialty journal (The Lancet. Neurology)
Journal's citation record	3 / 4	The Lancet Neurology: journal h-index 457 (OpenAlex, 2026-10-29)
Study design	7 / 12	A cohort study following people over time
Strength of evidence	3 / 5	Rated “moderate” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	1 / 5	2016 — within 20 year(s) of the newest study here
Sample size	2 / 4	218 participants
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	3 / 3	Studied in people (participant count stated)
Randomized / blinded	0 / 2	No randomization or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	5 / 7	Cited 272 times (OpenAlex, 2026-10-10)
Citations per year	4 / 5	22.7 citations a year over 12 year(s) since 2016
Impact for its field and year	5 / 6	Cited 20.2× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	2 / 6	Cited by 7 other studies in this library
Still being cited	3 / 4	Cited 77 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	3 / 4	Last-listed author Charlotte Cordonnier: h-index 77 (OpenAlex, whole career)
Institution's track record	2 / 3	Massachusetts General Hospital: institution h-index 2,057 (OpenAlex)
Multicenter collaboration	2 / 3	OpenAlex lists 4 institution(s) in 2 countries
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 27133238)
Free to read	0 / 2	Behind a paywall — scores zero
Total	66 / 100	—

What each of these 20 components measures, and what this score is not →

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