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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 16,026–16,050 of 27,380 studies, newest first · page 642 of 1096.

June 2016 13

  1. 2016-06-01

    Obstructive sleep apnea decreases central nervous system-derived proteins in the cerebrospinal fluid

    ✓ Peer-reviewed Tau biomarkers Annals of neurology

    Key finding: Other neuronally derived proteins, but not total protein, were also decreased in the OSA group, suggesting that OSA may affect the interaction between interstitial and cerebrospinal fluid.

    Full summary, score breakdown and related studies → Original source

  2. 2016-06-01

    Identifying and Managing Pain in People with Alzheimer's Disease and Other Types of Dementia: A Systematic Review

    ✓ Peer-reviewed End-of-life care CNS drugs

    Key finding: Despite increased use of analgesics, pain is still prevalent in people with dementia.

    Full summary, score breakdown and related studies → Original source

  3. 2016-06-01

    TFEB at a glance

    ✓ Peer-reviewed Disease mechanisms Journal of cell science

    Key finding: Recently, in vivo studies have revealed that TFEB is also involved in physiological processes, such as lipid catabolism. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2016-06-01

    A review of new insights on the association between hearing loss and cognitive decline in ageing

    ✓ Peer-reviewed Risk factors Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale

    Key finding: Age-related hearing loss (ARHL) has a multifactorial pathogenesis and it is an inevitable hearing impairment associated with reduction of communicative skills related to ageing.

    Full summary, score breakdown and related studies → Original source

  5. 2016-06-01

    Prediction of Individual Response to Electroconvulsive Therapy via Machine Learning on Structural Magnetic Resonance Imaging Data

    ✓ Peer-reviewed Hippocampus size on brain scans JAMA psychiatry

    Key finding: Both groups were compared with a sample of healthy control participants (n = 21). +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2016-06-01

    Motoric Cognitive Risk Syndrome and Falls Risk: A Multi-Center Study

    ✓ Peer-reviewed Clinical safety Journal of Alzheimer's disease : JAD

    Key finding: MCR is associated with an increased risk of falls. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2016-06-01

    Human TBK1: A Gatekeeper of Neuroinflammation

    ✓ Peer-reviewed Inflammation and the immune system Trends in molecular medicine

    Key finding: Gain-of-function of TBK1 are associated with NTG, whereas loss-of-function mutations result in ALS/FTD or in HSE. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2016-06-01

    Orexin-A is Associated with Increases in Cerebrospinal Fluid Phosphorylated-Tau in Cognitively Normal Elderly Subjects

    ✓ Peer-reviewed Tau biomarkers Sleep

    Key finding: Study objectives To evaluate the role of orexin-A with respect to cerebrospinal fluid (CSF) Alzheimer disease (AD) biomarkers, and explore its relationship to cognition and sleep characteristics in a group of cognitively normal elderly individuals. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2016-06-01

    Dissociation of Down syndrome and Alzheimer's disease effects with imaging

    ✓ Peer-reviewed Digital health tools Alzheimer's & dementia (New York, N. Y.)

    Key finding: These findings lay groundwork to enable AD clinical trials with characterization and disease-specific tracking of DS adults. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2016-06-01

    Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults

    ✓ Peer-reviewed Caregiving JAMA neurology

    Key finding: The use of AC medication was associated with increased brain atrophy and dysfunction and clinical decline. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2016-06-01

    Drug treatments in Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis Clinical medicine (London, England)

    Key finding: Despite the significant public health issue that it poses, only five medical treatments have been approved for Alzheimer's disease (AD) and these act to control symptoms rather than alter the course of the disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2016-06-01

    Hypothetical Preclinical Alzheimer Disease Groups and Longitudinal Cognitive Change

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: These results suggest that, to optimize observing a treatment effect, clinical trials enrolling cognitively normal individuals should selectively recruit participants with abnormal levels of both amyloid and tau (ie, stage 2) because this group would be expected to show the greatest cognitive decline over time if untreated. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2016-06-01

    Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: Eight single-nucleotide polymorphisms (false discovery rate P Conclusions and relevance Our findings demonstrate genetic overlap between AD and immune-mediated diseases and suggest that immune system processes influence AD pathogenesis and progression. +1 more finding

    Full summary, score breakdown and related studies → Original source

May 2016 12

  1. 2016-05-31

    Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease

    ✓ Peer-reviewed Vascular contributions Radiology

    Key finding: The results of this study showed global BBB leakage in patients with early AD that is associated with cognitive decline. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-05-31

    Acute hospital dementia care: results from a national audit

    ✓ Peer-reviewed Digital health tools BMC geriatrics

    Key finding: Most patients received physical assessments, including mobility (89 %), continence (84 %) and pressure sore risk (87 %); however assessment of pain (75 %), and particularly functioning (36 %) was poor. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2016-05-31

    Plasma β-amyloid in Alzheimer's disease and vascular disease

    ✓ Peer-reviewed How common it is Scientific reports

    Key finding: Plasma levels of Aβ42 and Aβ40 were reduced in AD dementia compared with all other diagnostic groups. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2016-05-30

    A large-scale comparison of cortical thickness and volume methods for measuring Alzheimer's disease severity

    ✓ Peer-reviewed Hippocampus size on brain scans NeuroImage. Clinical

    Key finding: We show that volume- and thickness-based measures generally perform similarly for separating clinically normal from AD populations, and in correlation with Braak neurofibrillary tangle stage at autopsy. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2016-05-30

    Remote Neuropsychological Assessment in Rural American Indians with and without Cognitive Impairment

    ✓ Peer-reviewed Disparities Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

    Key finding: The sample consisted of 84 participants from the Choctaw Nation in Oklahoma, including 53 females and 31 males [M age = 64.89 (SD = 9.73), M education = 12.58 (SD = 2.35)]. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2016-05-26

    Particulate Air Pollution and Fasting Blood Glucose in Nondiabetic Individuals: Associations and Epigenetic Mediation in the Normative Aging Study, 2000-2011

    ✓ Peer-reviewed Risk factors Environmental health perspectives

    Key finding: Among nondiabetics, short- and medium-term PM2.5 were associated with higher FBG. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2016-05-26

    Preclinical Characterization of 18F-MK-6240, a Promising PET Tracer for In Vivo Quantification of Human Neurofibrillary Tangles

    ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: A PET tracer is desired to help guide the discovery and development of disease-modifying therapeutics for neurodegenerative diseases characterized by neurofibrillary tangles (NFTs), the predominant tau pathology in Alzheimer disease (AD).

    Full summary, score breakdown and related studies → Original source

  8. 2016-05-26

    Pathophysiological Role of Neuroinflammation in Neurodegenerative Diseases and Psychiatric Disorders

    ✓ Peer-reviewed Inflammation and the immune system International neurourology journal

    Key finding: While the underlying mechanisms remain poorly understood, human and animal studies have supported a role of neuroinflammation in the etiology of these diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2016-05-26

    Defining the spectrum of frontotemporal dementias associated with TARDBP mutations

    ✓ Peer-reviewed Disparities Neurology. Genetics

    Key finding: We describe the largest series of patients with TARDBP mutations presenting with frontotemporal dementia (FTD) and review the cases in the literature to precisely characterize FTD diseases associated with this genotype. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2016-05-25

    Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease

    ✓ Peer-reviewed Treatments Frontiers in neuroscience

    Key finding: Although its etiology is not completely known, several factors including deficits of acetylcholine, β-amyloid deposits, τ-protein phosphorylation, oxidative stress, and neuroinflammation are considered to play significant roles in the pathophysiology of this disease.

    Full summary, score breakdown and related studies → Original source

  11. 2016-05-25

    Mitochondria-associated ER membranes and Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE Current opinion in genetics & development

    Key finding: The most widely accepted hypothesis is called the amyloid cascade, based on the observation that the brains of AD patients contain high levels of extracellular plaques, composed mainly of β-amyloid (Aβ), and intracellular tangles, composed of hyperphosphorylated forms of the microtubule-associated protein tau. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2016-05-24

    Self, cortical midline structures and the resting state: Implications for Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Neuroscience and biobehavioral reviews

    Key finding: Different aspects of the self have been reported to be affected in many neurological or psychiatric diseases such as Alzheimer's disease (AD), including mainly higher-level cognitive self-unawareness. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →