Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 15,901–15,925 of 27,380 studies, newest first · page 637 of 1096.
July 2016 25
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2016-07-28
Therapies for Prevention and Treatment of Alzheimer's Disease
43/100 ✓ Peer-reviewed Prevention and risk BioMed research international
Key finding: Alzheimer's disease (AD) is the most common cause of dementia associated with a progressive neurodegenerative disorder, with a prevalence of 44 million people throughout the world in 2015, and this figure is estimated to double by 2050. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-07-27
Resident Aggression and Abuse in Assisted Living
43/100 ✓ Peer-reviewed Health systems and care delivery Journal of applied gerontology : the official journal of the Southern Gerontological Society
Key finding: Dementia and severe mental illness were significant risk factors for all three types of resident aggression and abuse.
Full summary, score breakdown and related studies → Original source
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2016-07-27
General practitioners' perceptions of the barriers and solutions to good-quality palliative care in dementia
41/100 ✓ Peer-reviewed End-of-life care Dementia (London, England)
Key finding: These findings have significant implications for educators and clinicians as enhanced dementia education and training were highlighted as a strong agenda for GPs with the suggestions of dementia awareness programmes for the public.
Full summary, score breakdown and related studies → Original source
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2016-07-27
Care assistant experiences of dementia care in long-term nursing and residential care environments
32/100 ✓ Peer-reviewed Health systems and care delivery Dementia
Key finding: The study revealed important deficiencies in understanding and varying levels of dementia training.
Full summary, score breakdown and related studies → Original source
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2016-07-27
Seizures in dominantly inherited Alzheimer disease
56/100 ✓ Peer-reviewed Risk genes beyond APOE Neurology
Key finding: A national multicentric study was performed in patients with ADEOAD harboring a pathogenic mutation within PSEN1, PSEN2, APP, or a duplication of APP, and a minimal follow-up of 5 years. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-07-26
Experience of media presentations for the alleviation of agitation and emotional distress among dementia patients in a long-term nursing facility
43/100 ✓ Peer-reviewed Clinical safety Dementia
Key finding: The experience of natural scenes in dementia patients’ everyday atmosphere became a new and positive aspect of life at the long-term nursing facility, although the quantitative data did not significantly change during the project.
Full summary, score breakdown and related studies → Original source
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2016-07-26
Estimation of Tau and Phosphorylated Tau181 in Serum of Alzheimer’s Disease and Mild Cognitive Impairment Patients
40/100 ✓ Peer-reviewed Biomarkers PLoS ONE
Key finding: The concentrations of serum Tau and p-Tau181 were significantly higher (p<0.00001) in AD (Tau; 47.49±9.00ng/μL, p-Tau181; 0.161±0.04 ng/μL) compared to MCI (Tau; 39.26±7.78 ng/μL, p-Tau181; 0.135±0.02 ng/μL) and were further higher compared to elderly controls (Tau; 34.92±6.58 ng/μL, p-Tau181; 0.122±0.01 ng/ μL). +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-07-26
Neuroplasticity and Clinical Practice: Building Brain Power for Health
38/100 ✓ Peer-reviewed Cognitive tests and assessment Frontiers in psychology
Key finding: One goal is to provide an overview of the many ways new neuroscience can inform treatment protocols to empower and motivate clients to make the lifestyle choices that could help build brain power and could increase adherence to healthy lifestyle changes that have also been associated with simultaneously enhancing vigorous longevity, health, happiness, and wellness.
Full summary, score breakdown and related studies → Original source
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2016-07-26
Predicting dementia in primary care patients with a cardiovascular health metric: a prospective population-based study
55/100 ✓ Peer-reviewed Digital health tools BMC neurology
Key finding: Due to complex relationships of body-mass index and blood pressure with dementia individual components cancelled each other out and rendered the sum-scores meaningless for the prediction of dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-07-26
Robot-assisted laparoscopic prostatectomy versus open radical retropubic prostatectomy: early outcomes from a randomised controlled phase 3 study
76/100 ✓ Peer-reviewed Clinical trials Lancet (London, England)
Key finding: Between Aug 23, 2010, and Nov 25, 2014, 326 men were enrolled, of whom 163 were randomly assigned to radical retropubic prostatectomy and 163 to robot-assisted laparoscopic prostatectomy. 18 withdrew (12 assigned to radical retropubic prostatectomy and six assigned to robot-assisted laparoscopic prostatectomy); thus, 151 in the radical retropubic prostatectomy group proceeded to surgery and 157 in the robot-assisted laparoscopic prostatectomy group. 121 assigned to radical retropubic prostatectomy completed the 12 week questionnaire versus 131 assigned to robot-assisted laparoscopic prostatectomy. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-07-26
Does mild cognitive impairment always lead to dementia? A review
52/100 ✓ Peer-reviewed Mild cognitive impairment Journal of the neurological sciences
Key finding: Mild cognitive impairment (MCI) has often been studied in its association with dementia, yet higher rates of reversion to normal cognition than progression to dementia suggest that MCI does not necessarily lead to dementia. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-07-26
Effectiveness of a 6-year multidomain vascular care intervention to prevent dementia (preDIVA): a cluster-randomised controlled trial
79/100 ✓ Peer-reviewed How common it is Lancet (London, England)
Key finding: A nurse-led, multidomain intervention did not result in a reduced incidence of all-cause dementia in an unselected population of older people. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-07-25
APOE genotype and stress response - a mini review
38/100 ✓ Peer-reviewed Genetics Lipids in health and disease
Key finding: The APOE gene is one of currently only two genes that have consistently been associated with longevity. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-07-25
Imaging and cerebrospinal fluid biomarkers in early preclinical alzheimer disease
64/100 ✓ Peer-reviewed Brain scans and imaging Annals of neurology
Key finding: CSF Aβ42 levels are tightly coupled with cortical amyloid load in the earliest stages of preclinical AD, and begin to decrease dramatically prior to the point when an abnormal threshold of cortical accumulation is detected with amyloid imaging.
Full summary, score breakdown and related studies → Original source
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2016-07-23
Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls
41/100 ✓ Peer-reviewed Tau biomarkers Aging cell
Key finding: Compact hippocampal aggregates were purified from Alzheimer's and control-subject pools using magnetic-bead immunoaffinity pulldowns. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-07-22
Adherence to a Mediterranean-Style Diet and Effects on Cognition in Adults: A Qualitative Evaluation and Systematic Review of Longitudinal and Prospective Trials
67/100 ✓ Peer-reviewed Prevention trials Frontiers in nutrition
Key finding: Over the past 15 years, much empirical evidence supports the suggestion that a MedDiet may be beneficial with respect to reducing the incidence of cardiovascular disease, cancer, metabolic syndrome, and dementia. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-07-21
Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer's disease
40/100 ✓ Peer-reviewed Disease mechanisms Scientific reports
Key finding: Finally, we observe attenuated plaque-localised glial reactivity in these mice and significantly altered microglial morphology. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-07-21
Evaluation of the Digital Alzheimer Center: Testing Usability and Usefulness of an Online Portal for Patients with Dementia and Their Carers
39/100 ✓ Peer-reviewed Digital health tools JMIR research protocols
Key finding: In the usability assessment, eight categories of errors were distinguished, of which three were of critical, two of medium, and three of low severity.
Full summary, score breakdown and related studies → Original source
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2016-07-20
The bowel and beyond: the enteric nervous system in neurological disorders
36/100 ✓ Peer-reviewed Disease mechanisms Nature reviews. Gastroenterology & hepatology
Key finding: Animal models suggest that common pathophysiological mechanisms account for the frequency of gastrointestinal comorbidity in these conditions.
Full summary, score breakdown and related studies → Original source
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2016-07-20
A comprehensive compilation of SUMO proteomics
36/100 ✓ Peer-reviewed Genetics Nature reviews. Molecular cell biology
Key finding: Small ubiquitin-like modifiers (SUMOs) are essential for the regulation of several cellular processes and are potential therapeutic targets owing to their involvement in diseases such as cancer and Alzheimer disease. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-07-20
Clinical and cognitive trajectories in cognitively healthy elderly individuals with suspected non-Alzheimer's disease pathophysiology (SNAP) or Alzheimer's disease pathology: a longitudinal study
52/100 ✓ Peer-reviewed Prevention and risk The Lancet. Neurology
Key finding: The A(+)N(-) and A(+)N(+) groups had significantly faster cognitive decline than the A(-)N(-) group (0·08 SD per year for AIBL-Preclinical AD Cognitive Composite [PACC]; p<0·0001; and 0·25; p<0·0001; respectively). +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-07-19
Functional connectivity and microstructural white matter changes in phenocopy frontotemporal dementia
39/100 ✓ Peer-reviewed Brain scans and imaging European radiology
Key finding: PhFTD showed subtly increased DMN connectivity and subtle microstructural changes in frontal WM tracts. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-07-19
Low Cerebrospinal Fluid Amyloid-Beta Concentration Is Associated with Poorer Delayed Memory Recall in Women
45/100 ✓ Peer-reviewed Tau biomarkers Dementia and geriatric cognitive disorders extra
Key finding: In women we found a significant correlation between CSF amyloid-beta (Aβ1-42) and several subtests measuring delayed recall. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-07-19
Neurodegenerative and neurological disorders by small inhaled particles
47/100 ✓ Peer-reviewed Inflammation and the immune system Neurotoxicology
Key finding: In 2001, it was estimated that there were almost 5 million Europeans suffering from Alzheimer's disease (AD) and this figure has been projected to almost double by 2040. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-07-18
"Delirium Day": a nationwide point prevalence study of delirium in older hospitalized patients using an easy standardized diagnostic tool
54/100 ✓ Peer-reviewed Clinical safety BMC medicine
Key finding: Delirium occurred in more than one out of five patients in acute and rehabilitation hospital wards. +3 more findings
Full summary, score breakdown and related studies → Original source
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