Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 15,776–15,800 of 27,380 studies, newest first · page 632 of 1096.
September 2016 25
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2016-09-26
Bacteroides fragilis Lipopolysaccharide and Inflammatory Signaling in Alzheimer's Disease
40/100 ✓ Peer-reviewed Disease mechanisms Frontiers in microbiology
Key finding: The deleterious effects of these bacterial exudates appear to become more important as GI tract and blood-brain barriers alter or increase their permeability with aging and disease. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-23
Workplace violence in different settings and among various health professionals in an Italian general hospital: a cross-sectional study
48/100 ✓ Peer-reviewed Prevention and risk Psychology research and behavior management
Key finding: This study suggests that violence is a significant phenomenon and that all health workers, especially nurses, are at risk of suffering aggressive assaults. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-22
Extracellular Vesicle-Associated Aβ Mediates Trans-Neuronal Bioenergetic and Ca 2+ -Handling Deficits in Alzheimer's Disease Models
40/100 ✓ Peer-reviewed Biomarkers NPJ aging and mechanisms of disease
Key finding: Impairment of lysosome function results in increased generation EVs with elevated Aβ42 levels.
Full summary, score breakdown and related studies → Original source
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2016-09-22
Pharmacokinetic Evaluation of the Tau PET Radiotracer 18F-T807 (18F-AV-1451) in Human Subjects
44/100 ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Key finding: The percentage of unmetabolized 18 F-T807 in plasma followed a single exponential with a half-life of 17.0 ± 4.2 min. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-20
Family caregiver support groups: spiritual reflections' impact on stress management
39/100 ✓ Peer-reviewed Caregiving Aging & mental health
Key finding: Content analysis of the video-recorded group interactions yielded recurrent themes of caregivers' spiritual reflections and their associations with managing caregiver stress responses. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-09-20
The NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseases
40/100 ✓ Peer-reviewed Risk factors Particle and fibre toxicology
Key finding: Although classically studied in models of gout, Type II diabetes, Alzheimer's disease, and multiple sclerosis, the importance and mechanisms of action of inflammasome priming and activation have recently been elucidated in cells of the respiratory tract where they modulate the responses to a number of inhaled pathogenic particles and fibres. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-20
The Mediterranean Diet and Cognitive Function among Healthy Older Adults in a 6-Month Randomised Controlled Trial: The MedLey Study
57/100 ✓ Peer-reviewed Prevention trials Nutrients
Key finding: Evidence from a limited number of randomised controlled intervention trials (RCTs) have shown that a Mediterranean dietary pattern may reduce the risk of cognitive decline and enhance cognitive function among healthy older adults. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-20
Cerebrospinal Fluid Amyloid Beta and Tau Concentrations Are Not Modulated by 16 Weeks of Moderate- to High-Intensity Physical Exercise in Patients with Alzheimer Disease
45/100 ✓ Peer-reviewed Tau biomarkers Dementia and geriatric cognitive disorders
Key finding: Physical exercise may have some effect on cognition in patients with Alzheimer disease (AD). +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-19
Ocular indicators of Alzheimer's: exploring disease in the retina
43/100 ✓ Peer-reviewed Brain scans and imaging Acta neuropathologica
Key finding: In line with the above findings, animal model studies have reported retinal Aβ deposits and tauopathy, often correlated with local inflammation, retinal ganglion cell degeneration, and functional deficits. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-19
Evolving antithrombotic treatment patterns for patients with newly diagnosed atrial fibrillation
59/100 ✓ Peer-reviewed Vascular contributions Heart (British Cardiac Society)
Key finding: Since NOACs were introduced, there has been an increase in newly diagnosed patients with AF at risk of stroke receiving guideline-recommended therapy, predominantly driven by increased use of NOACs and reduced use of VKA±AP or AP alone. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-09-17
Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors
36/100 ✓ Peer-reviewed Risk factors Frontiers in neuroendocrinology
Key finding: Additionally, sex steroid hormones appear to contribute to AD risk, with age-related losses of estrogens in women and androgens in men associated with increased risk.
Full summary, score breakdown and related studies → Original source
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2016-09-16
Roles of hippocampal subfields in verbal and visual episodic memory
50/100 ✓ Peer-reviewed Hippocampus size on brain scans Behavioural brain research
Key finding: Our findings confirm previous research on the specific roles of CA1 and subiculum in episodic memory. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-16
Palliative care needs and symptoms of nursing home residents with and without dementia: A cross-sectional study
46/100 ✓ Peer-reviewed End-of-life care Geriatrics & gerontology international
Key finding: According to caregivers, residents with dementia experienced fewer other physical symptoms (e.g. nausea) than residents without dementia. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-09-16
The Diagnosis of Delirium Superimposed on Dementia: An Emerging Challenge
38/100 ✓ Peer-reviewed Clinical safety Journal of the American Medical Directors Association
Key finding: People who are older with dementia and who are institutionalized are at increased risk of developing delirium when hospitalized.
Full summary, score breakdown and related studies → Original source
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2016-09-16
Methylglyoxal in Metabolic Disorders: Facts, Myths, and Promises
38/100 ✓ Peer-reviewed Disease mechanisms Medicinal research reviews
Key finding: The MG has been implicated in classical diabetic complications such as retinopathy, nephropathy, and neuropathy, but has also been recently associated with cardiovascular diseases and central nervous system disorders such as cerebrovascular diseases and dementia. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-09-16
Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammation
47/100 ✓ Peer-reviewed Inflammation and the immune system Redox biology
Key finding: The molecular mechanisms underlying AD are still not clear, and at present no reliable biomarkers are available for the early diagnosis. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-16
Thyroid function and the risk of dementia: The Rotterdam Study
60/100 ✓ Peer-reviewed Long-term cohort studies Neurology
Key finding: Analyses were performed within the Rotterdam Study (baseline 1997), a prospective, population-based cohort. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-16
Digital life storybooks for people with dementia living in care homes: an evaluation
42/100 ✓ Peer-reviewed Digital health tools Clinical interventions in aging
Key finding: The result indicated that five of the six participants showed additional improvement in measures of quality of life and autobiographical memory. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-09-15
The Impact of Cognitive Training on Cerebral White Matter in Community-Dwelling Elderly: One-Year Prospective Longitudinal Diffusion Tensor Imaging Study
40/100 ✓ Peer-reviewed Prevention trials Scientific reports
Key finding: It has been shown that cognitive training (CogTr) is effective and recuperative for older adults, and can be used to fight against cognitive decline. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-15
Level of and Change in Cognitive Functioning among Dutch Older Adults: Does Neighborhood Socioeconomic Status Matter?
37/100 ✓ Peer-reviewed Risk factors Das Gesundheitswesen
Key finding: The analyses are based on more than 1,200 individuals aged 57 to 88 years at baseline in 1995. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-15
Mediterranean Diet, Cognitive Function, and Dementia: A Systematic Review of the Evidence
62/100 ✓ Peer-reviewed Prevention and risk Advances in nutrition (Bethesda, Md.)
Key finding: A growing body of evidence suggests that adherence to the Mediterranean diet (MD) may protect against cognitive decline and dementia. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-13
Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes
40/100 ✓ Peer-reviewed Risk genes beyond APOE PLoS ONE
Key finding: These pathologies are observed in an age-dependent manner in organoids derived from multiple familial AD (fAD) patients harboring amyloid precursor protein (APP) duplication or presenilin1 (PSEN1) mutation, compared to controls. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-13
The relation between mood, activity, and interaction in long-term dementia care
47/100 ✓ Peer-reviewed Cognitive tests and assessment Aging & mental health
Key finding: Fulfilling PwD's need for occupation and social interaction is consistent with a person-centred dementia care focus and should have priority in dementia care. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-09-09
Tau and tauopathies
36/100 ✓ Peer-reviewed Disease mechanisms Brain research bulletin
Key finding: In addition, it might be involved in regulating genome stability. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-09-09
Use of the Internet as a prevention tool against cognitive decline in normal aging
62/100 ✓ Peer-reviewed Prevention trials Clinical interventions in aging
Key finding: Recent demographic trends indicate that older people appear to be one of the fastest growing population groups worldwide. +1 more finding
Full summary, score breakdown and related studies → Original source
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